Results 11 to 20 of about 253,847 (119)

Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation

open access: yesVirology Journal, 2018
The cytoplasmic domain of lentiviral Envelopes (EnvCD) ensures Env incorporation into nascent virions and regulates Env trafficking to and from the plasma membrane.
Cyprien Beraud   +2 more
doaj   +1 more source

Assembly principles of a unique cage formed by hexameric and decameric E. coli proteins

open access: yeseLife, 2014
A 3.3 MDa macromolecular cage between two Escherichia coli proteins with seemingly incompatible symmetries–the hexameric AAA+ ATPase RavA and the decameric inducible lysine decarboxylase LdcI–is reconstructed by cryo-electron microscopy to 11 Å ...
Hélène Malet   +7 more
doaj   +1 more source

Virus–Host Cell Interactions

open access: yesCells, 2022
As obligate intracellular parasites, viruses are intimately interconnected with their host cells [...]
Thomas Hoenen, Allison Groseth
doaj   +1 more source

Viruses of Microbes 2020: The Latest Conquest on Viruses of Microbes

open access: yesViruses, 2021
This Special Issue celebrates viruses of microbes: those viruses that infect archaea, bacteria and microbial eukaryotes [...]
Tessa E. F. Quax   +2 more
doaj   +1 more source

The Landscape of Virus-Host Protein–Protein Interaction Databases

open access: yesFrontiers in Microbiology, 2022
Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions.
Gabriel Valiente
doaj   +1 more source

Structure-based mechanism of action of a viral poly(ADP-ribose) polymerase 1-interacting protein facilitating virus replication

open access: yesIUCrJ, 2018
Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that modifies nuclear proteins by poly(ADP-ribosyl)ation, regulates various cellular activities and restricts the lytic replication of oncogenic gammaherpesviruses by inhibiting the function of ...
Woo-Chang Chung   +7 more
doaj   +1 more source

Virus–Host Interactions in Foot-and-Mouth Disease Virus Infection

open access: yesFrontiers in Immunology, 2021
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which has been regarded as a persistent challenge for the livestock industry in many countries. Foot-and-mouth disease virus (FMDV) is the etiological agent of FMD that
Kangli Li   +5 more
doaj   +1 more source

Limited impact of hepatitis A virus 3C protease-mediated cleavage on the functions of NEMO in human hepatocytes

open access: yesJournal of Virology
NF-κB essential modulator (NEMO) is critically involved in the induction of interferons (IFNs) and pro-inflammatory cytokines. Hepatitis A virus (HAV) 3C protease was recently identified to cleave NEMO in non-hepatic cells.
Hao-En Huang   +3 more
doaj   +1 more source

Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data

open access: yeseLife, 2021
Background: Rapid identification and investigation of healthcare-associated infections (HCAIs) is important for suppression of SARS-CoV-2, but the infection source for hospital onset COVID-19 infections (HOCIs) cannot always be readily identified based ...
Oliver Stirrup   +16 more
doaj   +1 more source

Functional Landscape of African Swine Fever Virus–Host and Virus–Virus Protein Interactions

open access: yesViruses, 2023
Viral replication fully relies on the host cell machinery, and physical interactions between viral and host proteins mediate key steps of the viral life cycle.
Katarzyna Magdalena Dolata   +3 more
doaj   +1 more source

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