Results 11 to 20 of about 253,847 (119)
Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation
The cytoplasmic domain of lentiviral Envelopes (EnvCD) ensures Env incorporation into nascent virions and regulates Env trafficking to and from the plasma membrane.
Cyprien Beraud +2 more
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Assembly principles of a unique cage formed by hexameric and decameric E. coli proteins
A 3.3 MDa macromolecular cage between two Escherichia coli proteins with seemingly incompatible symmetries–the hexameric AAA+ ATPase RavA and the decameric inducible lysine decarboxylase LdcI–is reconstructed by cryo-electron microscopy to 11 Å ...
Hélène Malet +7 more
doaj +1 more source
As obligate intracellular parasites, viruses are intimately interconnected with their host cells [...]
Thomas Hoenen, Allison Groseth
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Viruses of Microbes 2020: The Latest Conquest on Viruses of Microbes
This Special Issue celebrates viruses of microbes: those viruses that infect archaea, bacteria and microbial eukaryotes [...]
Tessa E. F. Quax +2 more
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The Landscape of Virus-Host Protein–Protein Interaction Databases
Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions.
Gabriel Valiente
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Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that modifies nuclear proteins by poly(ADP-ribosyl)ation, regulates various cellular activities and restricts the lytic replication of oncogenic gammaherpesviruses by inhibiting the function of ...
Woo-Chang Chung +7 more
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Virus–Host Interactions in Foot-and-Mouth Disease Virus Infection
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which has been regarded as a persistent challenge for the livestock industry in many countries. Foot-and-mouth disease virus (FMDV) is the etiological agent of FMD that
Kangli Li +5 more
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NF-κB essential modulator (NEMO) is critically involved in the induction of interferons (IFNs) and pro-inflammatory cytokines. Hepatitis A virus (HAV) 3C protease was recently identified to cleave NEMO in non-hepatic cells.
Hao-En Huang +3 more
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Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data
Background: Rapid identification and investigation of healthcare-associated infections (HCAIs) is important for suppression of SARS-CoV-2, but the infection source for hospital onset COVID-19 infections (HOCIs) cannot always be readily identified based ...
Oliver Stirrup +16 more
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Functional Landscape of African Swine Fever Virus–Host and Virus–Virus Protein Interactions
Viral replication fully relies on the host cell machinery, and physical interactions between viral and host proteins mediate key steps of the viral life cycle.
Katarzyna Magdalena Dolata +3 more
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