Results 51 to 60 of about 119,805 (200)
Development of a Platform for Noncovalent Coupling of Full Antigens to Tobacco Etch Virus-Like Particles by Means of Coiled-Coil Oligomerization Motifs [PDF]
, 2021 Lorena Zapata-Cuellar +7 more
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
RNA Phage VLP-Based Vaccine Platforms
Pharmaceuticals, 2021 Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format.
David S. Peabody +3 more
doaj +1 more source
Influenza virus-like particle vaccines
Expert Review of Vaccines, 2009 Enveloped virus-like particle (VLP) vaccines containing influenza hemagglutinin (HA) and neuraminidase (NA) antigens are produced easily in insect or mammalian cells via the simultaneous expression of HA and NA along with a viral core protein, such as influenza matrix (M1) or a retroviral Gag protein.
openaire +2 more sources
Design Concepts of Virus-Like Particle-Based HIV-1 Vaccines
Frontiers in Immunology, 2020 Prophylactic vaccines remain the best approach for controlling the human immunodeficiency virus-1 (HIV-1) transmission. Despite the limited efficacy of the RV144 trial in Thailand, there is still no vaccine candidate that has been proven successful ...
Chun-Wei Chen +5 more
doaj +1 more source
Virus-like Particles for TEM Regulation and Antitumor Therapy
Journal of Functional Biomaterials, 2022 Tumor development and metastasis are intimately associated with the tumor microenvironment (TME), and it is difficult for vector-restricted drugs to act on the TME for long-term cancer immunotherapy.
Zhu Yang +5 more
doaj +1 more source
Virology Journal, 2017 Background Marburg virus (MARV) causes severe haemorrhagic fever in humans and nonhuman primates and has a high mortality rate. However, effective drugs or licensed vaccines are not currently available to control the outbreak and spread of this disease ...
Weiwei Gai +16 more
doaj +1 more source
Virus-like particles as vaccine adjuvants
Molecular Biotechnology, 2001 Virus-like particles (VLPs) consist of one or more viral coat proteins that assemble into particles. They can be taken up by antigen presenting cells (APC), peptides derived from them are presented on MHC class I molecules at the cell surface, and thereby prime a CD8+ T cell response, either against the particle-forming protein itself (such as ...
openaire +3 more sources
mSphere, 2020 For enteroviruses such as poliovirus (PV), empty capsids, which are antigenically indistinguishable from mature virions, are produced naturally during viral infection.
Lee Sherry +6 more
doaj +1 more source
Viruses, 2016 Marburg virus (MARV) was the first filovirus to be identified following an outbreak of viral hemorrhagic fever disease in Marburg, Germany in 1967. Due to several factors inherent to filoviruses, they are considered a potential bioweapon that could be ...
John M. Dye +8 more
doaj +1 more source