Results 61 to 70 of about 119,805 (200)

Virus-like particles in vaccine development

Expert Review of Vaccines, 2010
Virus-like particles (VLPs) are multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccine candidates. A handful of prophylactic VLP-based vaccines is currently commercialized worldwide: GlaxoSmithKline's Engerix (hepatitis B virus) and ...
António, Roldão, Maria Candida M, Mellado, Leda R, Castilho, Manuel J T, Carrondo, Paula M, Alves   +4 more
openaire   +2 more sources

Virus-like Particles of Nodavirus Displaying the Receptor Binding Domain of SARS-CoV-2 Spike Protein: A Potential VLP-Based COVID-19 Vaccine [PDF]

, 2023
Kiven Kumar, Wen Siang Tan, Siti Suri Arshad, Kok Lian Ho   +3 more
openalex   +1 more source

Incorporation of membrane-anchored flagellin or Escherichia coli heat-labile enterotoxin B subunit enhances the immunogenicity of rabies virus-like particles in mice and dogs

Frontiers in Microbiology, 2015
Rabies remains an important worldwide public health threat, so safe, effective and affordable vaccines are still being sought. Virus-like particle (VLP)-based vaccines targeting various viral pathogens have been successfully produced, licensed and ...
Yinglin eQi, Yinglin eQi, Hongtao eKang, Hongtao eKang, Xuexing eZheng, Hualei eWang, Yuwei eGao, Songtao eYang, Xianzhu eXia   +8 more
doaj   +1 more source

Figure S8 from Virus-Like Particle–Drug Conjugates Induce Protective, Long-lasting Adaptive Antitumor Immunity in the Absence of Specifically Targeted Tumor Antigens [PDF]

, 2023
Rhonda C. Kines, Cynthia D. Thompson, Sean Spring, Zhenyu Li, Elisabet de los Pinos, Stephen Monks, John T. Schiller   +6 more
openalex   +1 more source

Monoclonal antibodies against Hepatitis C genotype 3a virus like particle inhibit virus entry in cell culture system.

PLoS ONE, 2013
The envelope protein (E1-E2) of Hepatitis C virus (HCV) is a major component of the viral structure. The glycosylated envelope protein is considered to be important for initiation of infection by binding to cellular receptor(s) and also known as one of ...
Soma Das, Rohini K Shetty, Anuj Kumar, Radhika Nagamangalam Shridharan, Ranjitha Tatineni, Giriprakash Chi, Anirban Mukherjee, Saumitra Das, Shaila Melkote Subbarao, Anjali Anoop Karande   +9 more
doaj   +1 more source

An enterovirus A71 virus-like particle with replaced loops confers partial cross-protection in mice

, 2023
Xin Liu, Hanyu Zhu, Mei Wang, Ning Zhang, Jing Wang, W. L. Tan, Guochuan Wu, Pei Yu, Hongbo Liu, Qiliang Liu   +9 more
openalex   +1 more source

A Viral Platform for Chemical Modification and Multivalent Display

Journal of Nanobiotechnology, 2003
The ability to chemically modify the surfaces of viruses and virus-like particles makes it possible to confer properties that make them potentially useful in biotechnology, nanotechnology and molecular electronics applications. RNA phages (e.g. MS2) have
Peabody David S
doaj   +1 more source

SARS-CoV-2 and Epstein–Barr Virus-like Particles Associate and Fuse with Extracellular Vesicles in Virus Neutralization Tests [PDF]

, 2023
Johannes Roessler, Dagmar Pich, Verena Krähling, Stephan Becker, Oliver T. Keppler, Reinhard Zeidler, Wolfgang Hammerschmidt   +6 more
openalex   +1 more source

Virus-like particle vaccines: immunology and formulation for clinical translation

Expert Review of Vaccines, 2018
Introduction: Virus-like particle (VLP) vaccines face significant challenges in their translation from laboratory models, to routine clinical administration. While some VLP vaccines thrive and are readily adopted into the vaccination schedule, others are
Braeden Donaldson, Zabeen Lateef, Greg F. Walker, Sarah L. Young, Vernon K. Ward   +4 more
doaj   +1 more source

Virus-like particles: innate immune stimulators

Expert Review of Vaccines, 2011
Sub-virion particles, now known as virus-like particles (VLPs), were first purified from plasma samples of hepatitis B virus-infected patients in 1968 [1].
openaire   +2 more sources