Results 61 to 70 of about 583,625 (325)
High-speed imaging of ESCRT recruitment and dynamics during HIV virus like particle budding.
PLoS ONE, 2020 Endosomal sorting complexes required for transport proteins (ESCRT) catalyze the fission of cellular membranes during budding of membrane away from the cytosol.
Shilpa Gupta +2 more
doaj +1 more source
Structural and biophysical analysis of important biomedical enzymes and nano-architectures [PDF]
, 2008 Dopa decarboxylase (DDC) is an important enzyme in the catecholamine biosynthesis pathways. Catecholamines, e.g., dopamine, serotonin, etc. often are the major neuromodulators or neurotransmitters.
Chattopadhyay, Arundhati
core +1 more source
Thermally-responsive Virus-like Particle for Targeted Delivery of Cancer Drug
Scientific Reports, 2019 Multifunctional nanocarriers displaying specific ligands and simultaneously response to stimuli offer great potentials for targeted and controlled drug delivery.
Qiu Xian Thong +4 more
semanticscholar +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Next generation designer virus-like particle vaccines for dengue
Expert Review of Vaccines, 2019 Introduction: A safe and efficacious vaccine for dengue continues to be an unmet public health need. The recent licensing of a dengue vaccine (Dengvaxia) developed by Sanofi has brought to the fore the safety issue of vaccine-induced infection ...
Rahul Shukla +8 more
doaj +1 more source
PLoS ONE, 2014 Identifying safe and effective adjuvants is critical for the advanced development of protein-based vaccines. Pattern recognition receptor (PRR) agonists are increasingly being explored as potential adjuvants, but there is concern that the efficacy of ...
Karen A O Martins +8 more
doaj +1 more source
Viruses, 2022 Human parvovirus B19 (HPV B19) is pathogenic to human, which can cause fifth disease, transient aplastic crisis, arthritis, myocarditis, autoimmune disorders, hydrops fetalis, and so on.
Shuai Shao +12 more
doaj +1 more source
Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
, 2016 Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino +5 more
core +1 more source
Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine
Scientific Reports, 2017 The leading malaria vaccine in development is the circumsporozoite protein (CSP)-based particle vaccine, RTS,S, which targets the pre-erythrocytic stage of Plasmodium falciparum infection.
K. Collins +4 more
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source