Results 61 to 70 of about 722,631 (394)
A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates
Science Translational Medicine, 2019 A multivalent VLP vaccine protects against aerosol challenge of three lethal encephalitis viruses in mice and nonhuman primates. A triple threat to equine encephalitis viruses There are no approved treatments or vaccines for certain alphaviruses that can
S. Ko +21 more
semanticscholar +1 more source
Human Vaccines & Immunotherapeutics, 2017 Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (
Hye Suk Hwang +10 more
doaj +1 more source
Thermally-responsive Virus-like Particle for Targeted Delivery of Cancer Drug
Scientific Reports, 2019 Multifunctional nanocarriers displaying specific ligands and simultaneously response to stimuli offer great potentials for targeted and controlled drug delivery.
Qiu Xian Thong +4 more
semanticscholar +1 more source
Comparing particle-particle and particle-hole channels of random-phase approximation [PDF]
Phys. Rev. B 99, 195149 (2019), 2019 We present a comparative study of particle-hole and particle-particle channels of random-phase approximation (RPA) for molecular dissociations of different bonding types. We introduced a \textit{direct} particle-particle RPA scheme, in analogy to the \textit{direct} particle-hole RPA formalism, whereby the exchange-type contributions are excluded. This
arxiv +1 more source
Unified gas-kinetic wave-particle methods VI: Disperse dilute gas-particle multiphase flow [PDF]
, 2021 In this paper, a unified gas-kinetic wave-particle scheme (UGKWP) for the disperse dilute gas-particle multiphase flow is proposed. The gas phase is always in the hydrodynamic regime. However, the particle phase covers different flow regimes from particle trajectory crossing to the hydrodynamic wave interaction with the variation of local particle ...
arxiv +1 more source
Synthetic biology for bioengineering virus‐like particle vaccines
Biotechnology and Bioengineering, 2018 Vaccination is the most effective method of disease prevention and control. Many viruses and bacteria that once caused catastrophic pandemics (e.g., smallpox, poliomyelitis, measles, and diphtheria) are either eradicated or effectively controlled through
Hayley K Charlton Hume +5 more
semanticscholar +1 more source
One-Particle and Few-Particle Billiards [PDF]
, 2005 We study the dynamics of one-particle and few-particle billiard systems in containers of various shapes. In few-particle systems, the particles collide elastically both against the boundary and against each other. In the one-particle case, we investigate the formation and destruction of resonance islands in (generalized) mushroom billiards, which are a
arxiv +1 more source
Fluid particle dynamics: a synthesis of dissipative particle dynamics and smoothed particle dynamics [PDF]
, 1997 We present a generalization of dissipative particle dynamics that includes shear forces between particles. The new algorithm has the same structure as the (isothermal) smoothed particle dynamics algorithm, except that it conserves angular momentum and includes thermal fluctuations consistently with the principles of equilibrium statistical mechanics ...
arxiv +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Radiative View Factor Correlations in Particulate Media from Ray Tracing Simulations and Data-Driven Modeling [PDF]
arXiv, 2022 Thermal radiation in particulate media has been extensively modeled by solving the radiative transport equation with effective radiative properties or with statistical ray tracing techniques. While effective for static particles, this approach is not compatible with the more common discrete formulation of heat fluxes in particle flow systems.
arxiv