Results 11 to 20 of about 368,709 (305)
Virus-like particles in vaccine development
Expert Review of Vaccines, 2010 Virus-like particles (VLPs) are multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccine candidates. A handful of prophylactic VLP-based vaccines is currently commercialized worldwide: GlaxoSmithKline's Engerix (hepatitis B virus) and ...
António, Roldão +4 more
openaire +4 more sources
Production of mosquito cell-derived Zika virus-like particles using BacMos system
Journal of Medical Sciences, 2021 Background: Zika virus (ZIKV) is a mosquito-borne flavivirus which has been conclusively linked to Guillain-Barré syndrome and microcephaly. The worldwide emergence of ZIKV has greatly increased the demand for vaccines that reduce or prevent disease ...
Hui-Tsu Lin +2 more
doaj +1 more source
How promising are HIV-1-based virus-like particles for medical applications
Frontiers in Cellular and Infection Microbiology, 2022 New approaches aimed at identifying patient-specific drug targets and addressing unmet clinical needs in the framework of precision medicine are a strong motivation for researchers worldwide.
Sofia A. Martins +8 more
doaj +1 more source
Minimal system for assembly of SARS-CoV-2 virus like particles
Scientific Reports, 2020 SARS-CoV-2 virus is the causative agent of COVID-19. Here we demonstrate that non-infectious SARS-CoV-2 virus like particles (VLPs) can be assembled by co-expressing the viral proteins S, M and E in mammalian cells.
Heather Swann +7 more
doaj +1 more source
Vegetative incompatibility and potential involvement of a mycovirus in the Italian population of Geosmithia morbida [PDF]
, 2015 Studies carried out during an Italian outbreak of the Thousand Cankers Disease of walnut, demonstrated that non-coalescing cankers on host plants, separated by equidistant uninfected zones, were associated with incompatible strains of Geosmithia morbida.
Berton, Valeria +3 more
core +2 more sources
Viruses of protozoan parasites and viral therapy: Is the time now right?
Virology Journal, 2020 Infections caused by protozoan parasites burden the world with huge costs in terms of human and animal health. Most parasitic diseases caused by protozoans are neglected, particularly those associated with poverty and tropical countries, but the paucity ...
Paul Barrow +9 more
doaj +1 more source
Vaccine potential of Nipah virus-like particles. [PDF]
PLoS ONE, 2011 Nipah virus (NiV) was first recognized in 1998 in a zoonotic disease outbreak associated with highly lethal febrile encephalitis in humans and a predominantly respiratory disease in pigs.
Pramila Walpita +4 more
doaj +1 more source
Infection and Drug Resistance, 2023 Su-Hwa Lee,1,* Ki-Back Chu,2,* Min-Ju Kim,3 Fu-Shi Quan1,2 1Department of Medical Zoology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; 2Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical ...
Lee SH, Chu KB, Kim MJ, Quan FS
doaj
Dual-acting stapled peptides target both HIV-1 entry and assembly [PDF]
, 2013 Background: Previously, we reported the conversion of the 12-mer linear and cell-impermeable peptide CAI to a cell-penetrating peptide NYAD-1 by using an i,i + 4 hydrocarbon stapling technique and confirmed its binding to the C-terminal domain (CTD ...
Bhargava, P. +12 more
core +2 more sources
Optimizing the synthesis and purification of MS2 virus like particles
Scientific Reports, 2021 Introducing bacteriophage MS2 virus-like particles (VLPs) as gene and drug delivery tools increases the demand for optimizing their production and purification procedure.
Khadijeh Hashemi +6 more
doaj +1 more source