Results 11 to 20 of about 6,611,706 (299)
Programmable polymorphism of a virus-like particle [PDF]
Communications Materials, 2022 Virus-like particles are promising for drug delivery systems and vaccine development, but controlling their size and morphology is challenging. Here, amino acid sequences are inserted into MS2 bacteriophage virus-like particles, with their size and shape
Artur P. Biela +4 more
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Size-selective downstream processing of virus particles and non-enveloped virus-like particles
Frontiers in Bioengineering and Biotechnology, 2023 Non-enveloped virus-like particles (VLPs) are versatile protein nanoparticles with great potential for biopharmaceutical applications. However, conventional protein downstream processing (DSP) and platform processes are often not easily applicable due to
Nils Hillebrandt, Jürgen Hubbuch
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Infection and Drug Resistance, 2023 Su-Hwa Lee,1,* Ki-Back Chu,2,* Min-Ju Kim,3 Fu-Shi Quan1,2 1Department of Medical Zoology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; 2Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical ...
Lee SH, Chu KB, Kim MJ, Quan FS
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Platelet-like particles released from Ebola virus-infected megakaryocytic cells behave like virus-like particles. [PDF]
PLoS PathogensEbola virus (EBOV) is likely a zoonotic and re-emerging virus that causes severe outbreaks of Ebola virus disease. The virus spreads to various tissues during the late stage of infection and has been detected in immune-privileged sites of survivors ...
Makoto Kuroda, Peter J Halfmann
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Recent Progress on the Versatility of Virus-Like Particles
Vaccines, 2020 Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural proteins of a virus in the absence of genetic material. Having similar morphology to natural viruses but lacking any pathogenicity or infectivity, VLPs have ...
Ciying Qian +10 more
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Virus-Like Particles as an Immunogenic Platform for Cancer Vaccines
Viruses, 2020 Virus-like particles (VLP) spontaneously assemble from viral structural proteins. They are naturally biocompatible and non-infectious. VLP can serve as a platform for many potential vaccine epitopes, display them in a dense repeating array, and elicit ...
Jerri C. Caldeira +3 more
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Virus-like particles in vaccine development
Expert Review of Vaccines, 2010 Virus-like particles (VLPs) are multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccine candidates. A handful of prophylactic VLP-based vaccines is currently commercialized worldwide: GlaxoSmithKline's Engerix (hepatitis B virus) and ...
Manuel J T Carrondo +2 more
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Immunogenicity of Virus-like Particles Based on VP1 Protein of Bovine Norovirus [PDF]
Veterinary SciencesBovine Norovirus (BNoV) is a member of the enterovirus family that can cause gastroenteritis in calves. This virus poses a significant risk to calf growth and development as well as to the long-term sustainability of the cattle industry in China and ...
Zhigang Ma +13 more
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Analysis of dynamics of human parvovirus B19 virus-like particles [PDF]
, 2023 岩手大学博士（学術）原著論文 Ishida K, Noguchi T, Kimura S, Suzuki H, Ebina H, Morita E. Tracking of Human Parvovirus B19 Virus-Like Particles Using Short Peptide Tags Reveals a Membrane-Associated Extracellular Release of These Particles Journal of Virology 97(2 ...
石田, 幸太郎
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Virus-like Particles: Measures and Biological Functions
Viruses, 2022 Virus-like particles resemble infectious virus particles in size, shape, and molecular composition; however, they fail to productively infect host cells.
Tara Bhat, Amy Cao, John Yin
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