Results 21 to 30 of about 203,768 (257)
How promising are HIV-1-based virus-like particles for medical applications
Frontiers in Cellular and Infection Microbiology, 2022 New approaches aimed at identifying patient-specific drug targets and addressing unmet clinical needs in the framework of precision medicine are a strong motivation for researchers worldwide.
Sofia A. Martins +8 more
doaj +1 more source
Norwalk virus-like particles as vaccines [PDF]
Expert Review of Vaccines, 2010 Noroviruses (NoV) cause the great majority of epidemic nonbacterial gastroenteritis in humans. Expression of the capsid protein in recombinant systems, including insect and plant cells, yields assembly of virus-like particles (VLPs) that mimic the antigenic structure of authentic virions, and are relatively acid- and heat-stable.
Melissa, Herbst-Kralovetz +2 more
openaire +2 more sources
Minimal system for assembly of SARS-CoV-2 virus like particles
Scientific Reports, 2020 SARS-CoV-2 virus is the causative agent of COVID-19. Here we demonstrate that non-infectious SARS-CoV-2 virus like particles (VLPs) can be assembled by co-expressing the viral proteins S, M and E in mammalian cells.
Heather Swann +7 more
doaj +1 more source
Vaccine potential of Nipah virus-like particles. [PDF]
PLoS ONE, 2011 Nipah virus (NiV) was first recognized in 1998 in a zoonotic disease outbreak associated with highly lethal febrile encephalitis in humans and a predominantly respiratory disease in pigs.
Pramila Walpita +4 more
doaj +1 more source
Infection and Drug Resistance, 2023 Su-Hwa Lee,1,* Ki-Back Chu,2,* Min-Ju Kim,3 Fu-Shi Quan1,2 1Department of Medical Zoology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; 2Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical ...
Lee SH, Chu KB, Kim MJ, Quan FS
doaj
Viruses of protozoan parasites and viral therapy: Is the time now right?
Virology Journal, 2020 Infections caused by protozoan parasites burden the world with huge costs in terms of human and animal health. Most parasitic diseases caused by protozoans are neglected, particularly those associated with poverty and tropical countries, but the paucity ...
Paul Barrow +9 more
doaj +1 more source
Optimizing the synthesis and purification of MS2 virus like particles
Scientific Reports, 2021 Introducing bacteriophage MS2 virus-like particles (VLPs) as gene and drug delivery tools increases the demand for optimizing their production and purification procedure.
Khadijeh Hashemi +6 more
doaj +1 more source
Virus like particles as a platform for cancer vaccine development [PDF]
PeerJ, 2017 Cancers have killed millions of people in human history and are still posing a serious health problem worldwide. Therefore, there is an urgent need for developing preventive and therapeutic cancer vaccines.
Hui Kian Ong, Wen Siang Tan, Kok Lian Ho
doaj +2 more sources
Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development
Viruses, 2020 In the midst of the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause epidemics and pandemics with significant human mortality.
Peter Pushko, Irina Tretyakova
doaj +1 more source
PLoS ONE, 2021 The present work addresses the thermal remodelling of flexible plant viruses with a helical structure and virus-like particles (VLPs). Here, for the first time, the possibility of filamentous Alternanthera mosaic virus (AltMV) virions' thermal transition
Tatiana I Manukhova +6 more
doaj +1 more source