Evaluation of electrospray differential mobility analysis for virus particle analysis: Potential applications for biomanufacturing. [PDF]
, 2011 The technique of electrospray differential mobility analysis (ES-DMA) was examined as a potential potency assay for routine virus particle analysis in biomanufacturing environments (e.g., evaluation of vaccines and gene delivery products for lot release)
Brorson, Kurt A +4 more
core +1 more source
Adjuvant-containing control arms in pivotal quadrivalent human papillomavirus vaccine trials: Restoration of previously unpublished methodology [PDF]
, 2020 Purpose: Trustworthy reporting of quadrivalent human papillomavirus (HPV) vaccine trials is the foundation for assessing the vaccine's risks and benefits.
Bourgeois, Florence +7 more
core +1 more source
Virus like particles as a platform for cancer vaccine development [PDF]
PeerJ, 2017 Cancers have killed millions of people in human history and are still posing a serious health problem worldwide. Therefore, there is an urgent need for developing preventive and therapeutic cancer vaccines.
Hui Kian Ong, Wen Siang Tan, Kok Lian Ho
doaj +2 more sources
Population dynamics of an RNA virus and its defective interfering particles in passage cultures [PDF]
, 2010 Background Viruses can fall prey to their defective interfering (DI) particles. When viruses are cultured by serial passage on susceptible host cells, the presence of virus-like DI particles can cause virus populations to rise and fall, reflecting ...
Kristen Thompson, John Yin
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Unnatural Amino Acid Incorporation into Virus-Like Particles [PDF]
, 2008 Virus-like particles composed of hepatitis B virus (HBV) or bacteriophage Qβ capsid proteins have been labeled with azide- or alkyne-containing unnatural amino acids by expression in a methionine auxotrophic strain of E. coli.
Brown, Steven +11 more
core +2 more sources
A Compensatory Liability Regime to Promote the Exchange of Microbial Genetic Resources for Research and Benefit Sharing [PDF]
, 2011 Female rhesus macaques were immunized with HIV virus-like particles (HIV-VLPs) or HIV DNA administered as sequential combinations of mucosal (intranasal) and systemic (intramuscular) routes, according to homologous or heterologous prime-boost schedules ...
Andersen, Hanne +10 more
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Norwalk virus-like particles as vaccines [PDF]
Expert Review of Vaccines, 2010 Noroviruses (NoV) cause the great majority of epidemic nonbacterial gastroenteritis in humans. Expression of the capsid protein in recombinant systems, including insect and plant cells, yields assembly of virus-like particles (VLPs) that mimic the antigenic structure of authentic virions, and are relatively acid- and heat-stable.
Melissa, Herbst-Kralovetz +2 more
openaire +2 more sources
Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development
Viruses, 2020 In the midst of the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause epidemics and pandemics with significant human mortality.
Peter Pushko, Irina Tretyakova
doaj +1 more source
PLoS ONE, 2021 The present work addresses the thermal remodelling of flexible plant viruses with a helical structure and virus-like particles (VLPs). Here, for the first time, the possibility of filamentous Alternanthera mosaic virus (AltMV) virions' thermal transition
Tatiana I Manukhova +6 more
doaj +1 more source
Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]
, 2001 In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Kroese, M.V. +3 more
core +2 more sources