Optimizing the synthesis and purification of MS2 virus like particles
Introducing bacteriophage MS2 virus-like particles (VLPs) as gene and drug delivery tools increases the demand for optimizing their production and purification procedure.
Khadijeh Hashemi +6 more
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Electron microscopic, immunofluorescent and virological studies on a rhabdomyosarcoma in epidermodysplasia verruciformis [PDF]
A subcutaneous tumor of a patient with epidermodysplasia verruciformis was studied by the light microscopy, the electronmicroscopy and the immunofluorescent test.
Koyama, Hiroko, Yabe, Yoshiro
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Virus-like particles in the plant hopper Javesella pellucida Fab. [PDF]
Javesella pellucida Fab. (Homoptera, Delphacidae) is one of two plant hoppers known to transmit the pathogen called European wheat striate mosaic virus (EWSMV) (Kisimoto & Watson, 1965) which has not yet been purified or identified visually (Serjeant ...
Watson, M. A. +3 more
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Construction and characterization of chimaeric human immunodefiency virus type 1 subtype C Gag virus-like particles [PDF]
Includes bibliographical references (leaves 114-128).In this study I explored the possibility of making HIV-1 subtype C Pr55gag-based chimaeric virus-like particles (VLPs) as a boost to the HIV-IC multigene DNA vaccine pTHr.grttnC, which encodes a ...
Halsey, Richard James
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Role of nonstructural protein NS2A in flavivirus assembly [PDF]
Flavivirus nonstructural (NS) proteins are involved in RNA replication and modulation of the host antiviral response; however, evidence is mounting that some NS proteins also have essential roles in virus assembly.
Pijlman, G.P. +5 more
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Virus Like Particles: A Self-Assembled Toolbox for Cancer Therapy [PDF]
Nanoparticle-based therapeutics have been applied in a broad range of clinical and pre-clinical applications from diagnosis to treatment for cancer. A wide range of synthetic and naturally occurring materials such as polymers, metal oxides, silicate ...
Olivia R, Brohlin +6 more
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Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development
In the midst of the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause epidemics and pandemics with significant human mortality.
Peter Pushko, Irina Tretyakova
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The present work addresses the thermal remodelling of flexible plant viruses with a helical structure and virus-like particles (VLPs). Here, for the first time, the possibility of filamentous Alternanthera mosaic virus (AltMV) virions' thermal transition
Tatiana I Manukhova +6 more
doaj +1 more source
The structural basis for the integrity of adenovirus Ad3 dodecahedron [PDF]
During the viral life cycle adenoviruses produce excess capsid proteins. Human adenovirus serotype 3 (Ad3) synthesizes predominantly an excess of free pentons, the complexes of pentameric penton base and trimeric fiber proteins, which are responsible for
Fender, Pascal +48 more
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Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity [PDF]
Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with ...
Owens, Ray +48 more
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