Results 31 to 40 of about 6,611,706 (299)

Virus like particles as a platform for cancer vaccine development [PDF]

PeerJ, 2017
Cancers have killed millions of people in human history and are still posing a serious health problem worldwide. Therefore, there is an urgent need for developing preventive and therapeutic cancer vaccines.
Hui Kian Ong, Wen Siang Tan, Kok Lian Ho
doaj   +2 more sources

Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. [PDF]

, 2013
BACKGROUND: Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and
Roy, Polly, Bishnupriya Bhattacharya, Bhattacharya, Bishnupriya, Polly Roy   +3 more
core   +1 more source

Optimizing the synthesis and purification of MS2 virus like particles

Scientific Reports, 2021
Introducing bacteriophage MS2 virus-like particles (VLPs) as gene and drug delivery tools increases the demand for optimizing their production and purification procedure.
Khadijeh Hashemi, Mohammad Mahdi Ghahramani Seno, Mohammad Reza Ahmadian, Bizhan Malaekeh-Nikouei, Mohammad Reza Bassami, Hesam Dehghani, Amir Afkhami-Goli   +6 more
doaj   +1 more source

Virus-like particles in the plant hopper Javesella pellucida Fab. [PDF]

, 1970
Javesella pellucida Fab. (Homoptera, Delphacidae) is one of two plant hoppers known to transmit the pathogen called European wheat striate mosaic virus (EWSMV) (Kisimoto & Watson, 1965) which has not yet been purified or identified visually (Serjeant ...
Watson, M. A., Ammar, E. D., Milne, R. G.   +2 more
core   +1 more source

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity [PDF]

, 2013
Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with ...
Owens, Ray, Paramasivam, S, Kotecha, A, Wilsden, G, Parida, Satya, Paton, David, Ren, Junyuan, Al-Khalil, Tara, Belsham, Graham J., Lomonossoff, GP, Li, Yanmin, Belsham, GJ, Loureiro, S, Kotecha, Abhay, Belsham, Graham, Owens, R, Stuart, David I, Lomonossoff, George P., Porta, C, Xu, X, Parida, S, Lomonossoff, George P, Burman, Alison, Paton, D, Jones, IM, Curry, S, Blesham, Graham J., Paramasivam, Saravanan, Xu, Xiaodong, Stuart, DI, Charleston, Bryan, Jackson, T, Charleston, B, Burman, A, Jones, Ian M., Porta, Claudine, Ren, J, Stuart, David I., Fry, E, Stuart, David, Jones, Ian M, Ferris, N, Ferris, Nigel, Loureiro, Silvia, Belsham, Graham J, Curry, Stephen, Jackson, Terry, Al-Khalil, T, Li, Y, Fry, Elizabeth, Wilsden, Ginette   +50 more
core   +1 more source

Construction and characterization of chimaeric human immunodefiency virus type 1 subtype C Gag virus-like particles [PDF]

, 2006
Includes bibliographical references (leaves 114-128).In this study I explored the possibility of making HIV-1 subtype C Pr55gag-based chimaeric virus-like particles (VLPs) as a boost to the HIV-IC multigene DNA vaccine pTHr.grttnC, which encodes a ...
Halsey, Richard James
core   +1 more source

Alterations of membrane curvature during influenza virus budding [PDF]

, 2014
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
core   +1 more source

Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development

Viruses, 2020
In the midst of the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause epidemics and pandemics with significant human mortality.
Peter Pushko, Irina Tretyakova
doaj   +1 more source

Thermal remodelling of Alternanthera mosaic virus virions and virus-like particles into protein spherical particles.

PLoS ONE, 2021
The present work addresses the thermal remodelling of flexible plant viruses with a helical structure and virus-like particles (VLPs). Here, for the first time, the possibility of filamentous Alternanthera mosaic virus (AltMV) virions' thermal transition
Tatiana I Manukhova, Ekaterina A Evtushenko, Alexander L Ksenofontov, Alexander M Arutyunyan, Angelina O Kovalenko, Nikolai A Nikitin, Olga V Karpova   +6 more
doaj   +1 more source

Protein Cargo Encapsulation by Virus-Like Particles: Strategies and Applications [PDF]

, 2022
Viruses and the recombinant protein cages assembled from their structural proteins, known as virus-like particles (VLPs), have gained wide interest as tools in biotechnology and nanotechnology.
Noor, Dashti, Frank, Sainsbury, Li Chen, Cheah, Donna, McNeale   +3 more
core   +1 more source