Results 21 to 30 of about 731,035 (329)
Virus-like Particles as Nanocarriers for Intracellular Delivery of Biomolecules and Compounds
Viruses, 2022 Virus-like particles (VLPs) are nanostructures assemble from viral proteins. Besides widely used for vaccine development, VLPs have also been explored as nanocarriers for cargo delivery as they combine the key advantages of viral and non-viral vectors ...
Junyao He +6 more
semanticscholar +1 more source
Virus-like Particles as Preventive and Therapeutic Cancer Vaccines
Vaccines, 2022 Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native virus structure without being infectious. VLPs, similarly to wild type viruses, are able to efficiently target and activate dendritic cells (DCs) triggering the ...
A. Tornesello +4 more
semanticscholar +1 more source
In Vitro Assembly of Virus-Like Particles and Their Applications
Life, 2021 Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery. Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous compared to in vivo assembly, because it avoids encapsidation of host ...
Dinh To Le, K. Müller
semanticscholar +1 more source
Production of mosquito cell-derived Zika virus-like particles using BacMos system
Journal of Medical Sciences, 2021 Background: Zika virus (ZIKV) is a mosquito-borne flavivirus which has been conclusively linked to Guillain-Barré syndrome and microcephaly. The worldwide emergence of ZIKV has greatly increased the demand for vaccines that reduce or prevent disease ...
Hui-Tsu Lin +2 more
doaj +1 more source
How promising are HIV-1-based virus-like particles for medical applications
Frontiers in Cellular and Infection Microbiology, 2022 New approaches aimed at identifying patient-specific drug targets and addressing unmet clinical needs in the framework of precision medicine are a strong motivation for researchers worldwide.
Sofia A. Martins +8 more
doaj +1 more source
Construction of SARS-CoV-2 Virus-Like Particles by Mammalian Expression System
Frontiers in Bioengineering and Biotechnology, 2020 Virus-like particle (VLP) is a self-assembled nanostructure incorporating key viral structural proteins. VLP resembles molecular and morphological features of authentic viruses but is non-infectious and non-replicating due to lack of genetic materials ...
R. Xu +4 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs). DCs are the most potent antigen presenting cells (APCs) and their activation prompts the priming of immunity mediators based on B and T cells.
Jesús Zepeda-Cervantes +2 more
semanticscholar +1 more source
Viruses of protozoan parasites and viral therapy: Is the time now right?
Virology Journal, 2020 Infections caused by protozoan parasites burden the world with huge costs in terms of human and animal health. Most parasitic diseases caused by protozoans are neglected, particularly those associated with poverty and tropical countries, but the paucity ...
Paul Barrow +9 more
doaj +1 more source
Vaccine potential of Nipah virus-like particles. [PDF]
PLoS ONE, 2011 Nipah virus (NiV) was first recognized in 1998 in a zoonotic disease outbreak associated with highly lethal febrile encephalitis in humans and a predominantly respiratory disease in pigs.
Pramila Walpita +4 more
doaj +1 more source
Evaluation of electrospray differential mobility analysis for virus particle analysis: Potential applications for biomanufacturing. [PDF]
, 2011 The technique of electrospray differential mobility analysis (ES-DMA) was examined as a potential potency assay for routine virus particle analysis in biomanufacturing environments (e.g., evaluation of vaccines and gene delivery products for lot release)
Brorson, Kurt A +4 more
core +1 more source