Results 111 to 120 of about 263,074 (309)
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Cell-free system for assembly of transcriptionally repressed chromatin from Drosophila Embryos [PDF]
, 1992 We descrtbe a cell·free system, derlved (rom preblastoderm DrosophÜIJ embryos. ror tbe efficient assembly of eloned DNA into chromatin. Tbe cbromatin assembly system ulilizes cndogcDous eure histones aod assembly racton aod yields loog arrays of ...
Earl Wu +3 more
core
The C-Terminal Helical Domain of Dengue Virus Precursor Membrane Protein Is Involved in Virus Assembly and Entry [PDF]
, 2012 The role of the alpha-helical domain MH of dengue virus DENV precursor membrane protein in replication was investigated by site-directed mutagenesis.
謝思嘉;蔡文揚;張光正;王維恭 +1 more
core +1 more source
Advanced Functional Materials, EarlyView.The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett +19 more
wiley +1 more source
The Effects of Viral Structural Proteins on Acidic Phospholipids in Host Membranes
VirusesEnveloped viruses rely on host membranes for trafficking and assembly. A substantial body of literature published over the years supports the involvement of cellular membrane lipids in the enveloped virus assembly processes.
Ricardo de Souza Cardoso, Akira Ono
doaj +1 more source
Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery
Advanced Functional Materials, EarlyView.This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar +4 more
wiley +1 more source
RNA packaging and uncoating in simple single-stranded RNA viruses [PDF]
, 2012 Simple (non-enveloped) small, positive-sense single-stranded RNA viruses infect hosts from all kingdoms of life. However, their assembly and uncoating processes remain poorly understood. For turnip crinkle virus (TCV), 3D reconstructions by cryoelectron
Bakker, Saskia
core
Journal of VirologyThree capsid types have been recognized from the nuclei of herpesvirus-infected cells: empty A-capsids, scaffolding-containing B-capsids, and DNA-filled C-capsids.
Alexander Stevens +6 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Journal of VirologyTo become infectious, assembling enveloped viruses must acquire viral glycoproteins to mediate downstream infection events. Human immunodeficiency virus-1 (HIV-1) envelope glycoproteins (Env) are well characterized to function as trimers for membrane ...
Nicholas S. Groves +8 more
doaj +1 more source