Results 111 to 120 of about 2,979,740 (254)
Advanced Materials Technologies, EarlyView.Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina +5 more
wiley +1 more source
Journal of VirologyTo become infectious, assembling enveloped viruses must acquire viral glycoproteins to mediate downstream infection events. Human immunodeficiency virus-1 (HIV-1) envelope glycoproteins (Env) are well characterized to function as trimers for membrane ...
Nicholas S. Groves +8 more
doaj +1 more source
Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications
Advanced Materials Technologies, EarlyView.This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo +2 more
wiley +1 more source
, 2012 The role of the alpha-helical domain MH of dengue virus DENV precursor membrane protein in replication was investigated by site-directed mutagenesis.
謝思嘉;蔡文揚;張光正;王維恭 +1 more
core +1 more source
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Advanced Science, EarlyView.Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider +14 more
wiley +1 more source
Advanced Science, EarlyView.Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu +13 more
wiley +1 more source
Cryotomography of budding influenza a virus reveals filaments with diverse morphologies that mostly do not bear a genome at their distal end [PDF]
, 2013 Influenza viruses exhibit striking variations in particle morphology between strains. Clinical isolates of influenza A virus have been shown to produce long filamentous particles while laboratory-adapted strains are predominantly spherical.
Swetha Vijayakrishnan +29 more
core +1 more source
A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans
Advanced Science, EarlyView.This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao +19 more
wiley +1 more source
Virus-Templated Assembly of Porphyrins into Light-Harvesting Nanoantennae
, 2016 Virus-Templated Assembly of Porphyrins into Light-Harvesting ...
Katherine Choi (2319904) +7 more
core +1 more source