Results 141 to 150 of about 243,139 (310)

The Utility of Data Transformation for Alignment, <em>de novo</em> Assembly and Classification of Short Read Virus Sequences

, 2019
Avraam Tapinos, Bede Constantinides, My V. T. Phan, Samaneh Kouchaki, Matthew Cotten, David L. Robertson   +5 more
openalex   +2 more sources

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

A physical model for M1-mediated influenza A virus assembly. [PDF]

Biophys J
Peukes J, Dmitrieff S, Nédélec FJ, Briggs JAG.   +3 more
europepmc   +2 more sources

Assessing the de novo assemblers: a metaviromic study of apple and first report of citrus concave gum-associated virus, apple rubbery wood virus 1 and 2 infecting apple in India

BMC Genomics
Background The choice of de novo assembler for high-throughput sequencing (HTS) data remains a pivotal factor in the HTS-based discovery of viral pathogens.
Zainul A. Khan, Susheel Kumar Sharma, Nitika Gupta, Damini Diksha, Pooja Thapa, Mailem Yazing Shimray, Malyaj R. Prajapati, Sajad U. Nabi, Santosh Watpade, Mahendra K. Verma, Virendra K. Baranwal   +10 more
doaj   +1 more source

Screening for Novel Small-Molecule Inhibitors Targeting the Assembly of Influenza Virus Polymerase Complex by a Bimolecular Luminescence Complementation-Based Reporter System [PDF]

, 2016
Chunfeng Li, Zining Wang, Yang Cao, Lulan Wang, Jingyun Ji, Zhigao Chen, Tao Deng, Taijiao Jiang, Genhong Cheng, F. Xiao‐Feng Qin   +9 more
openalex   +1 more source

Cholesterol‐DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

Advanced Materials Interfaces, EarlyView.
Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung, Young‐Joo Kim, Kunwoo Noh, Sunmi Lee, Minsuk Kwak   +4 more
wiley   +1 more source

Role of NS2 specific RNA binding and phosphorylation in liquid-liquid phase separation and virus assembly. [PDF]

Nucleic Acids Res, 2022
Rahman SK, Ampah KK, Roy P.
europepmc   +1 more source

Assembly of Hepatitis B Virus Envelope Proteins onto a Lentivirus Pseudotype That Infects Primary Human Hepatocytes [PDF]

, 2007
Ning Chai, Ho Eun Chang, Émmanuelle Nicolas, Severin O. Gudima, Jinhong Chang, John M. Taylor   +5 more
openalex   +1 more source

Label‐Free Sensing of Coronaviral Sequences via Kretschmann‐Configuration Reflectance Spectroscopic Ellipsometry: Sensitivity, Specificity, and Interfacial Effects

Advanced Materials Interfaces, EarlyView.
Spectroscopic ellipsometry in the Kretschmann‐Raether configuration (KRSE) is employed to characterize a DNA‐functionalized platform for viral sequence recognition. By merging SE with surface plasmon resonance, KRSE outperforms conventional SE, achieving nanomolar targeting through resonance wavelength shifts (δλ) measurements. Its enhanced interfacial
Silvia Maria Cristina Rotondi, Paolo Canepa, Francesco Bisio, Ornella Cavalleri, Maurizio Canepa   +4 more
wiley   +1 more source

A Small Loop in the Capsid Protein of Moloney Murine Leukemia Virus Controls Assembly of Spherical Cores

, 2006
Marcy R. Auerbach, Kristy Brown, Artem Kaplan, Denise de Las Nueces, Ila Singh   +4 more
openalex   +1 more source