Results 181 to 190 of about 2,979,740 (254)

Rational design of self-assembled RNA nanostructures for HIV-1 virus assembly blockade. [PDF]

Nucleic Acids Res, 2022
Qu N, Ying Y, Qin J, Chen AK.
europepmc   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly. [PDF]

Proc Natl Acad Sci U S A, 2022
Fang Q, Tang WC, Fokine A, Mahalingam M, Shao Q, Rossmann MG, Rao VB.   +6 more
europepmc   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Editorial: Viral interactions with the nucleus, volume II

Frontiers in Microbiology
Francesco Ciccarese, Xiaonan Zhang, Shadi Shahriari, Reena Ghildyal   +3 more
doaj   +1 more source

Herpes simplex virus assembly and spread in murine skin after infection from the outside. [PDF]

J Virol
Richardo T, Liu X, Döhner K, Chao T-Y, Buch A, Binz A, Pohlmann A, de le Roi M, Baumgärtner W, Brand K, Bauerfeind R, Förster R, Sodeik B, Halle S.   +13 more
europepmc   +1 more source

Lipid-protein interactions in virus assembly and budding from the host cell plasma membrane. [PDF]

Biochem Soc Trans, 2021
Motsa BB, Stahelin RV.
europepmc   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source

Scanning transmission electron tomography to study virus assembly: Review for the retirement of Paul Walther. [PDF]

J Microsc
Wieczorek S, Krijnse Locker J.
europepmc   +1 more source

Abstract Representation of Movement Parameters in Basal Ganglia Output

Advanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero, Diana I. Ortega‐Romero, Claudia I. Pérez‐Díaz, Pavel E. Rueda‐Orozco   +3 more
wiley   +1 more source