Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]
, 2010 Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel +16 more
core +1 more source
Viruses, 2019 Hepatitis E virus (HEV) infection is a major cause of acute hepatitis worldwide. It is transmitted enterically but replicates in the liver. Recent studies indicate that HEV exists in two forms: naked, nonenveloped virions that are shed into feces to ...
Xin Yin, Zongdi Feng
doaj +1 more source
Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion [PDF]
, 2010 Expert opinion was elicited to undertake a qualitative risk assessment to estimate the current and future risks to the European Union (EU) from five vector-borne viruses listed by the World Organization for Animal Health.
Brouwer, A. +7 more
core +1 more source
Entry properties and entry inhibitors of a human H7N9 influenza virus. [PDF]
PLoS ONE, 2014 The recently identified human infections with a novel avian influenza H7N9 virus in China raise important questions regarding possible risk to humans. However, the entry properties and tropism of this H7N9 virus were poorly understood.
Youhui Si +10 more
doaj +1 more source
PLoS ONE, 2010 Acid dependent infection of Hela and Vero cells by BTV-10 occurs from within early-endosomes following virus uptake by clathrin-mediated endocytosis (Forzan et al., 2007: J Virol 81: 4819-4827).
Sarah Gold +3 more
doaj +1 more source
Single virus tracking of Ebola virus entry through lipid rafts in living host cells
Biosafety and Health, 2020 Ebola virus (EBOV) is one of the most pathogenic viruses in humans which can cause a lethal hemorrhagic fever. Understanding the cellular entry mechanisms of EBOV can promote the development of new therapeutic strategies to control virus replication and ...
Cong Jin +9 more
doaj +1 more source
Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]
, 2010 Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Bitzegeio, Julia +10 more
core +2 more sources
Exploiting Herpes Simplex Virus Entry for Novel Therapeutics
Viruses, 2013 Herpes Simplex virus (HSV) is associated with a variety of diseases such as genital herpes and numerous ocular diseases. At the global level, high prevalence of individuals who are seropositive for HSV, combined with its inconspicuous infection, remains ...
Deepak Shukla, Satvik Hadigal
doaj +1 more source
Association between disruption of CD4 receptor dimerization and increased human immunodeficiency virus type 1 entry [PDF]
, 2006 Affiliation: Département de microbiologie et immunologie, Faculté de médecine, Université de Montréal & Institut de Recherches Cliniques de MontréalBACKGROUND:Human immunodeficiency virus (HIV) enters target cells by a membrane fusion process that ...
Bourgeois, Rachel +3 more
core +3 more sources
Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]
, 2009 Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter +5 more
core +2 more sources