Results 31 to 40 of about 595,205 (256)

Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells. [PDF]

, 2006
Cell entry of hepatitis C virus, pseudoparticles (HCVpp) and cell culture grown virus (HCVcc), requires the interaction of viral glycoproteins with CD81 and other as yet unknown cellular factors.
Boullier, Agnès, Lindenbach, Brett D, McKeating, Jane A, Paulson, Matthew, Quehenberger, Oswald, Rice, Charles M, von Hahn, Thomas   +6 more
core   +1 more source

Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent.

PLoS ONE, 2011
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Elena Rahn, Philipp Petermann, Mei-Ju Hsu, Frazer J Rixon, Dagmar Knebel-Mörsdorf   +4 more
doaj   +1 more source

Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

Nature Communications, 2020
The mechanism underlying the cellular entry of Zika virus is not fully understood. Here, the authors use a chemically modified virus and time-resolved proteomics to capture interacting host proteins during virus entry and identify NCAM1 as a ZIKV ...
Mayank Srivastava, Ying Zhang, Jian Chen, Devika Sirohi, Andrew Miller, Yang Zhang, Zhilu Chen, Haojie Lu, Jianqing Xu, Richard J. Kuhn, W. Andy Tao   +10 more
doaj   +1 more source

The role of cellular adhesion molecules in virus attachment and entry [PDF]

, 2015
As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core   +1 more source

Characterization of dengue virus entry into HepG2 cells [PDF]

, 2009
Background Despite infections by the dengue virus being a significant problem in tropical and sub-tropical countries, the mechanism by which the dengue virus enters into mammalian cells remains poorly described.
Lukkana Suksanpaisan, Tharinee Susantad, Duncan R Smith   +2 more
core   +2 more sources

HSPA4 Enhances BRSV Entry via Clathrin-Mediated Endocytosis Through Regulating the PI3K–Akt Signaling Pathway and ATPase Activity of HSC70

Viruses
Bovine respiratory syncytial virus (BRSV) is an enveloped RNA virus that utilizes clathrin-mediated endocytosis for cell entry and is a significant pathogen in bovine respiratory disease (BRD).
Yang Liu, Qiongyi Li, Shuai Shao, Xiaolan Ji, Wanning Gao, Yiyang Fan, Mingqi Liu, Yan Wang, Jialin Bai   +8 more
doaj   +1 more source

Ephrin-B2 expression critically influences Nipah virus infection independent of its cytoplasmic tail [PDF]

, 2008
Background Cell entry and cell-to-cell spread of the highly pathogenic Nipah virus (NiV) requires binding of the NiV G protein to cellular ephrin receptors and subsequent NiV F-mediated fusion.
Augustin Hellmut G, Pfaff Dennis, Erbar Stephanie, Diederich Sandra, Thiel Lena, Maisner Andrea   +5 more
core   +2 more sources

Complement-Mediated Virus Infectivity Neutralisation by HLA Antibodies Is Associated with Sterilising Immunity to SIV Challenge in the Macaque Model for HIV/AIDS. [PDF]

, 2014
Sterilising immunity is a desired outcome for vaccination against human immunodeficiency virus (HIV) and has been observed in the macaque model using inactivated simian immunodeficiency virus (SIV).
A Morner, Adriano Boasso, AJ Hessell, B Hahn, BL Sullivan, BL Sullivan, D Montefiori, DH Barouch, EG Hulskotte, EJ Stott, EJ Stott, EJ Stott, EJ Stott, EJ Stott, G Hunsmann, GB Karlsson Hedestam, GT Spear, GT Spear, H Akari, H Jiang, H Mouquet, H Mouquet, H Stoiber, HX Liao, J Chojnacki, J Rose, James Stott, JF Bower, JG Leith, JR Carlson, JR Mascola, LO Arthur, LO Arthur, M Gardner, M Huber, M Murphey-Corb, M Page, M Spruth, Mark Hassall, Mark Page, Mark Robinson, Martin Cranage, MP Cranage, MP Cranage, Neil Almond, P Putkonen, QJ Sattentau, R Hofmann-Lehmann, R Le Grand, RC Desrosiers, RP Johnson, Ruby Quartey-Papafio, S Ranjbar, S Willey, SW Barnett, TW Baba, VM Hirsch, WL Chan, WL Chan, X Wei, Y Wang, YML Valim   +61 more
core   +9 more sources

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating

mBio, 2020
While the basic mechanisms of flavivirus entry and fusion are understood, little is known about the postfusion events that precede RNA replication, such as nucleocapsid disassembly. We describe here a sensitive, conditionally replication-defective yellow
Harish N. Ramanathan, Shuo Zhang, Florian Douam, Katrina B. Mar, Jinhong Chang, Priscilla L. Yang, John W. Schoggins, Alexander Ploss, Brett D. Lindenbach   +8 more
doaj   +3 more sources