An update on vitamin B12-related gene polymorphisms and B12 status. [PDF]
, 2018 Vitamin B12 is an essential micronutrient in humans needed for health maintenance. Deficiency of vitamin B12 has been linked to dietary, environmental and genetic factors. Evidence for the genetic basis of vitamin B12 status is poorly understood. However,
A Adaikalakoteswari +106 more
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Advanced Science, EarlyView.Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
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Advanced Science, EarlyView.The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu +10 more
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Characterization of Vitamin B12 Supplementation and Correlation with Clinical Outcomes in a Large Longitudinal Study of Early Parkinson's Disease. [PDF]
, 2019 ObjectiveIn Parkinson's disease (PD), vitamin B12 levels are lower, and comorbid B12 deficiency has been associated with the development of neuropathy and early gait instability.
Christine, Chadwick W +3 more
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Microbially produced vitamin B12 contributes to the lipid-lowering effect of silymarin [PDF]
, 2023 Wenlong Sun +5 more
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Advanced Science, EarlyView.Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li +3 more
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HUBUNGAN ASUPAN ZAT BESI, ASAM FOLAT, VITAMIN B12 DAN VITAMIN C DENGAN KADAR HEMOGLOBIN SISWA DI SMP NEGERI 2 TAWANGHARJO KABUPATEN GROBOGAN [PDF]
, 2016 Anemia merupakan penurunan jumlah massa eritrosit atau massa hemoglobin sehingga tidak dapat memenuhi fungsinya untuk membawa oksigen dalam jumlah yang cukup ke jaringan perifer.
SAPTYASIH, ARENDA REKA NARIMA
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Principles for Rigorous Design and Application of Synthetic Microbial Communities
Advanced Science, EarlyView.SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source
Correlations between the Composition of the Bovine Microbiota and Vitamin B12 Abundance
mSystems, 2020 Vitamin B12 is synthesized by prokaryotes in the rumens of dairy cows—and this has implications in human nutrition since humans rely on consumption of dairy products for vitamin B12 acquisition. However, the concentration of vitamin B12 in milk is highly
Julian Franco-Lopez +11 more
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Vitamin B12 and progression of white matter lesions. A 2-year follow-up study in first-ever lacunar stroke patients. [PDF]
PLoS ONE, 2013 In cross-sectional studies periventricular white matter lesions (WML) were related to low plasma levels of vitamin B12. Whether low vitamin B12 levels are also related to progression of WML is still unknown. We studied baseline vitamin B12 levels and its
Ellen C van Overbeek +2 more
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