Results 41 to 50 of about 119,689 (246)

Nanoparticle transport in epithelial cells: pathway switching through bioconjugation [PDF]

open access: yes, 2013
The understanding and control of nanoparticle transport into and through cellular compartments is central to biomedical applications of nanotechnology. Here, it is shown that the transport pathway of 50 nm polystyrene nanoparticles decorated with vitamin
Alexander, Cameron   +9 more
core   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

open access: yesAdvanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo   +6 more
wiley   +1 more source

Correlations between the Composition of the Bovine Microbiota and Vitamin B12 Abundance

open access: yesmSystems, 2020
Vitamin B12 is synthesized by prokaryotes in the rumens of dairy cows—and this has implications in human nutrition since humans rely on consumption of dairy products for vitamin B12 acquisition. However, the concentration of vitamin B12 in milk is highly
Julian Franco-Lopez   +11 more
doaj   +1 more source

Vitamin B12 and progression of white matter lesions. A 2-year follow-up study in first-ever lacunar stroke patients. [PDF]

open access: yesPLoS ONE, 2013
In cross-sectional studies periventricular white matter lesions (WML) were related to low plasma levels of vitamin B12. Whether low vitamin B12 levels are also related to progression of WML is still unknown. We studied baseline vitamin B12 levels and its
Ellen C van Overbeek   +2 more
doaj   +1 more source

Utilization of cognitive support in episodic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older [PDF]

open access: yes, 2004
Apolipoprotein E (APOE), vitamin B12, and folate were examined in relation to free recall among 167 community-based older adults. Cognitive support at encoding and retrieval was also taken into account.
Bunce, D, Kivipelto, M, Wahlin, A
core  

Is there an association of vitamin B12 status with neurological function in older people? A systematic review. [PDF]

open access: yes, 2015
Low vitamin B12 status is common in older people; however, its public health significance in terms of neurological manifestations remains unclear. The present systematic review evaluated the association of vitamin B12 status with neurological function ...
Clarke, Robert   +3 more
core   +1 more source

Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions

open access: yesAdvanced Science, EarlyView.
Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley   +1 more source

HUBUNGAN ASUPAN ZAT BESI, ASAM FOLAT, VITAMIN B12 DAN VITAMIN C DENGAN KADAR HEMOGLOBIN SISWA DI SMP NEGERI 2 TAWANGHARJO KABUPATEN GROBOGAN [PDF]

open access: yes, 2016
Anemia merupakan penurunan jumlah massa eritrosit atau massa hemoglobin sehingga tidak dapat memenuhi fungsinya untuk membawa oksigen dalam jumlah yang cukup ke jaringan perifer.
SAPTYASIH, ARENDA REKA NARIMA
core   +2 more sources

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

open access: yesAdvanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang   +14 more
wiley   +1 more source

Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics. [PDF]

open access: yes, 2010
Background/objectivesA common polymorphism, C776G, in the plasma B12 transport protein transcobalamin (TC), encodes for either proline or arginine at codon 259.
Allen, LH   +4 more
core   +2 more sources

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