A derivative of vitamin B3 applied several days after exposure reduces lethality of severely irradiated mice [PDF]
Scientific Reports, 2021 Most, if not all, of the hitherto tested substances exert more or less pronounced pro-survival effects when applied before or immediately after the exposure to high doses of ionizing radiation.
Aneta Cheda +5 more
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Nicotinamide: A cardioprotective form of Vitamin B3 [PDF]
Arhiv za farmacijuNicotinamide, a form of vitamin B3, has emerged as a potential cardioprotective agent against ischemia-reperfusion (I/R) injury, a critical factor in the pathogenesis of myocardial infarction, heart failure, and other cardiovascular diseases.
Du Qingyou
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Vitamin B3 Provides Neuroprotection via Antioxidative Stress in a Rat Model of Anterior Ischemic Optic Neuropathy [PDF]
Antioxidants, 2022 Supplementing with vitamin B3 has been reported to protect against retinal ganglion cell (RGC) damage events and exhibit multiple neuroprotective properties in a mouse model of optic nerve injury.
Tu-Wen Chen +6 more
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Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS [PDF]
Molecules, 2021 Water-soluble B vitamins participate in numerous crucial metabolic reactions and are critical for maintaining our health. Vitamin B deficiencies cause many different types of diseases, such as dementia, anaemia, cardiovascular disease, neural tube ...
Sundus M. Sallabi +3 more
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Nature-inspired remodeling of (aza)indoles to meta-aminoaryl nicotinates for late-stage conjugation of vitamin B3 to (hetero)arylamines [PDF]
Nature Communications, 2020 Vitamin B3 derivatives display a range of biological activities. Here, the authors report the synthesis of meta-aminoaryl nicotinates, derivatives of vitamin B3, and their late-stage conjugation with (hetero)arylamines, ultimately expanding the chemical ...
Begur Vasanthkumar Varun +3 more
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Minireview Exploring the Biological Cycle of Vitamin B3 and Its Influence on Oxidative Stress: Further Molecular and Clinical Aspects [PDF]
Molecules, 2020 Vitamin B3, or niacin, is one of the most important compounds of the B-vitamin complex. Recent reports have demonstrated the involvement of vitamin B3 in a number of pivotal functions which ensure that homeostasis is maintained.
Bogdan Doroftei +9 more
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The chemistry of the vitamin B3 metabolome. [PDF]
Biochem Soc Trans, 2019 Abstract The functional cofactors derived from vitamin B3 are nicotinamide adenine dinucleotide (NAD+), its phosphorylated form, nicotinamide adenine dinucleotide phosphate (NADP+) and their reduced forms (NAD(P)H). These cofactors, together referred as the NAD(P)(H) pool, are intimately implicated in all essential bioenergetics ...
Makarov MV, Trammell SAJ, Migaud ME.
europepmc +5 more sources
COVID-19: Are We Facing Secondary Pellagra Which Cannot Simply Be Cured by Vitamin B3? [PDF]
Int J Mol Sci, 2022 Novak Kujundžić R.
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The female mouse is resistant to mild vitamin B3 deficiency. [PDF]
Eur J Nutr, 2022 van der Stelt I +7 more
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Vitamin B3 Triggers Biosynthesis of Secondary Metabolite Dormancy Signals in Streptococcus suis. [PDF]
J Am Chem Soc, 2022 Covington BC, Seyedsayamdost MR.
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