Nature-inspired remodeling of (aza)indoles to meta-aminoaryl nicotinates for late-stage conjugation of vitamin B3 to (hetero)arylamines [PDF]
Nature Communications, 2020 Vitamin B3 derivatives display a range of biological activities. Here, the authors report the synthesis of meta-aminoaryl nicotinates, derivatives of vitamin B3, and their late-stage conjugation with (hetero)arylamines, ultimately expanding the chemical ...
Begur Vasanthkumar Varun +3 more
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A derivative of vitamin B3 applied several days after exposure reduces lethality of severely irradiated mice [PDF]
Scientific Reports, 2021 Most, if not all, of the hitherto tested substances exert more or less pronounced pro-survival effects when applied before or immediately after the exposure to high doses of ionizing radiation.
Aneta Cheda +5 more
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Vitamin B3 Provides Neuroprotection via Antioxidative Stress in a Rat Model of Anterior Ischemic Optic Neuropathy [PDF]
Antioxidants, 2022 Supplementing with vitamin B3 has been reported to protect against retinal ganglion cell (RGC) damage events and exhibit multiple neuroprotective properties in a mouse model of optic nerve injury.
Tu-Wen Chen +6 more
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Jurnal Vokasi Kesehatan, 2022 Pola makan tidak seimbang merupakan salah satu pemicu terjadinya abnormalitas profil lipid, yang merupakan prediktor dari Penyakit Jantung Koroner (PJK).
Yoan Anggraeni Saputri +3 more
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Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS [PDF]
Molecules, 2021 Water-soluble B vitamins participate in numerous crucial metabolic reactions and are critical for maintaining our health. Vitamin B deficiencies cause many different types of diseases, such as dementia, anaemia, cardiovascular disease, neural tube ...
Sundus M. Sallabi +3 more
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The Therapeutic Potential of Vitamins B1, B3 and B6 in Charcot–Marie–Tooth Disease with the Compromised Status of Vitamin-Dependent Processes [PDF]
Biology, 2023 Understanding the molecular mechanisms of neurological disorders is necessary for the development of personalized medicine. When the diagnosis considers not only the disease symptoms, but also their molecular basis, treatments tailored to individual ...
Victoria Bunik
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Minireview Exploring the Biological Cycle of Vitamin B3 and Its Influence on Oxidative Stress: Further Molecular and Clinical Aspects [PDF]
Molecules, 2020 Vitamin B3, or niacin, is one of the most important compounds of the B-vitamin complex. Recent reports have demonstrated the involvement of vitamin B3 in a number of pivotal functions which ensure that homeostasis is maintained.
Bogdan Doroftei +9 more
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A novel and sensitive method for determining vitamin B3 and B7 by pre-column derivatization and high-performance liquid chromatography method with fluorescence detection. [PDF]
PLoS ONE, 2018 A new labeling reagent for vitamin analysis, 2-amino-10-ethyl acridine ketone (AEAO), has been synthesized and successfully applied to the analysis of vitamin B3 and vitamin B7 in different tea samples.
Baolei Fan +3 more
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The nutritional levels and status of vitamins among children in Henan, China [PDF]
Frontiers in NutritionBackgroundVitamins are vital for children’s health, and deficiencies can cause disorders, compromising quality of life and survival. This study systematically assesses multivitamin levels, nutritional status, and associated factors in children from Henan,
Xiaojuan Li +6 more
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Water-Soluble Vitamins (Riboflavin, Niacin, Pantothenic Acid) in Dogs with Chronic Liver Disease vs. Healthy Controls [PDF]
Veterinary SciencesBackground: Water-soluble vitamin deficiencies are common in human chronic liver disease (CLD) due to impaired metabolic pathways. Vitamins B2 (riboflavin), B3 (niacin), and B5 (pantothenic acid) assume critical roles in hepatic and lipid metabolism and ...
Verena Habermaass +5 more
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