The VLDL receptor regulates membrane progesterone receptor trafficking and non-genomic signaling [PDF]
, 2018 Nancy Nader +6 more
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Obesity, Volume 34, Issue 2, Page 357-371, February 2026.ABSTRACT Objective This longitudinal study aims to identify the key factors influencing the weight loss trajectory during a 24‐week intervention and their relevance at different stages of the treatment. Methods We studied 1252 participants (age 18–65 years) of a cognitive behavioral program to lose weight.
Rocío De la Peña‐Armada +4 more
wiley +1 more source
Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal. [PDF]
, 2019 Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying ...
Christian, Parul +9 more
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Liver International, Volume 46, Issue 2, February 2026.ABSTRACT Background and Aims Dyslipidemia is common in patients with MASLD, but the frequency and significance of inherited disorders of dyslipidemia are unclear. We investigated the prevalence and significance of pathogenic variants associated with selected monogenic disorders of dyslipidemia in 3358 patients with well‐characterised MASLD. Approach We
Tae‐Hwi Schwantes‐An +12 more
wiley +1 more source
Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin [PDF]
, 2003 Coen Wiegman +8 more
openalex +1 more source
Association of lipid composition and unsaturated fatty acids of VLDL with atrial remodeling in metabolic syndrome [PDF]
, 2023 Hsiang‐Chun Lee +5 more
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Low Cholesterol due to APOB Variants: Exploring the Balance Between Liver and Cardiovascular Risk
Liver International, Volume 46, Issue 2, February 2026.ABSTRACT Background & Aims Lifelong APOB gene inactivation lowers LDL‐C and cardiovascular risk, but impairs hepatic lipoprotein export, predisposing to chronic liver disease (CLD). The extent to which common steatogenic factors modulate this risk remains unclear.
Alessia Di Costanzo +12 more
wiley +1 more source
Proteomic Analysis of the Very Low Density Lipoprotein (VLDL) transport vesicles
, 2012 Rahimin Affandi Abdul Rahim +7 more
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A Somatic Mutation in HIF‐2α Affects Glucose and Lipid Metabolism via CD36 and Ceramide
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.A mutation within the C‐terminal transactivation domain of HIF‐2α enhances Cd36 expression by increased transactivation activity, leading to ceramide accumulation and disruption of glucose and lipid metabolism. Inhibition of ceramide synthesis by myriocin reduces ceramide levels and ameliorates these metabolic disturbances.
Feiqiong Gao +9 more
wiley +1 more source
Circulation ResearchThe production and secretion of VLDLs (very-low-density lipoproteins) by hepatocytes has a direct impact on liver fat content, as well as the concentrations of cholesterol and triglycerides in the circulation and thus affects both liver and cardiovascular health, respectively. Importantly, insulin resistance, excess caloric intake, and lack of physical
Van Zwol, Willemien +3 more
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