Results 81 to 90 of about 29,344 (206)

Spatio-Temporal Analysis of the Tularemia Agent Population in the Rostov Region, DPR, LPR and Ukraine from 1943 to 2023

Проблемы особо опасных инфекций
The aim of the study was to conduct spatio-temporal retrospective and operational genetic analysis of the tularemia agent population in the Rostov Region, Donetsk People’s Republic (DPR), Lugansk PR and Ukraine in the period of 1943–2023.
V. M. Sorokin, N. V. Pavlovich, M. V. Tsimbalistova, N. V. Aronova, A. S. Vodop’yanov, R. V. Pisanov, A. K. Noskov   +6 more
doaj   +1 more source

Impact of diversity of Mycoplasma hyopneumoniae strains on lung lesions in slaughter pigs [PDF]

, 2017
The importance of diversity of Mycoplasma hyopneumoniae (M. hyopneumoniae) strains is not yet fully known. This study investigated the genetic diversity of M.
Arsenakis, Ioannis, Boyen, Filip, Del Pozo Sacristán, Rubén, Haesebrouck, Freddy, Maes, Dominiek, Michiels, Annelies, Piepers, Sofie, Vranckx, Katleen   +7 more
core   +2 more sources

Characterization of three VNTR systems at D21S112

Genomics, 1992
D21S112 is a highly polymorphic marker on the long arm of chromosome 21. Our analysis of this locus indicated the presence of three VNTR systems. We estimated the heterozygosity of each system and sequenced one of the repetitive regions. Utilizing PCR, we demonstrated that the sequenced VNTR is responsible for the system with the highest level of ...
N, Takaesu, S, Newfeld, T, Hassold
openaire   +2 more sources

Human Endogenous Retroviruses and Diseases

MedComm, Volume 6, Issue 11, November 2025.
Human endogenous retroviruses (HERVs), remnants of ancient retroviral integrations into the human genome, are modulated by viral infections, genetic inheritance, and triggers including environmental factors, epigenetic dysregulation, oncogene activation, and aging.
Can Chen, Yanru Cui, Shixiang Wang, Yuze Yang, Zunpeng Liu, Suhan Jin, Fangqian Shen, Udo Gaipl, Hu Ma, Jian‐Guo Zhou   +9 more
wiley   +1 more source

Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.

PLoS ONE, 2009
Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly
Iñaki Comas, Susanne Homolka, Stefan Niemann, Sebastien Gagneux   +3 more
doaj   +1 more source

LINE-1 ORF1p does not determine substrate preference for human/orangutan SVA and gibbon LAVA

Mobile DNA, 2020
Background Non-autonomous VNTR (Variable Number of Tandem Repeats) composite retrotransposons – SVA (SINE-R-VNTR-Alu) and LAVA (L1-Alu-VNTR-Alu) – are specific to hominoid primates. SVA expanded in great apes, LAVA in gibbon.
Annette Damert
doaj   +1 more source

Genetic Basis of the Negative Response to the Use of Triptans for the Treatment of Migraine—A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 10, October 2025.
To systematize the genetic basis correctly associated with nonresponse to triptan, we revised etiological studies on Web of Science, Embase, and PubMed until 2023. We found that only polymorphisms in the SLC6A4, 5‐HT1B, and COMT genes have a stronger association with this condition. More robust studies are needed to increase this certainty.
Victoria Gomes Andreata, Ruan Pablo Duarte Freitas, Jéssica da Silva Nascimento, Patrícia Sodré Araújo, Felipe Eustáquio dos Santos Guedes, João Vítor Benjamim Pires, Narel Moita Carneiro Nogueira Falcão, Natasha da Silva Leitão, Alcylene Carla de Jesus dos Santos, Ana Patrícia Pascoal Queiroz, Astria Ferrão Dias Gonzales, Maica Matos Leão, Emília Katiane Embiruçu de Araújo Leão, Juliana Côrtes Freitas, Acássia Benjamim Leal Pires   +14 more
wiley   +1 more source

Humanized Mouse Models for Type 1 Diabetes

Current Protocols, Volume 5, Issue 10, October 2025.
Abstract T cell–mediated autoimmune type 1 diabetes (T1D) is under complex polygenic control in both humans and the NOD mouse model. However, in both species, particular major histocompatibility complex (MHC; designated HLA in humans) haplotypes provide the primary T1D risk factor. Both MHC/HLA class I and II variants interactively contribute to T1D by
David V. Serreze, Marissa Tousey‐Pfarrer, Jeremy J. Racine   +2 more
wiley   +1 more source

Evaluation of white spot syndrome virus variable DNA loci as molecular markers of virus spread at intermediate spatiotemporal scales [PDF]

, 2010
Variable genomic loci have been employed in a number of molecular epidemiology studies of white spot syndrome virus (WSSV), but it is unknown which loci are suitable molecular markers for determining WSSV spread on different spatiotemporal scales ...
Bui Thi Minh Dieu, Marks, H., Vlak, J.M., Zwart, M.P.   +3 more
core   +3 more sources

RepeatOBserver: Tandem Repeat Visualisation and Putative Centromere Detection

Molecular Ecology Resources, Volume 25, Issue 7, October 2025.
ABSTRACT Tandem repeats play an important role in centromere structure, subtelomeric regions, DNA methylation, recombination and the regulation of gene activity. Analysis of their distribution in genomes offers a potential means for predicting putative centromere locations, which continues to be a challenge for genome annotation.
Cassandra Elphinstone, Rob Elphinstone, Marco Todesco, Loren H. Rieseberg   +3 more
wiley   +1 more source