Results 91 to 100 of about 33,802 (280)

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

A Putative Role of Voltage-Dependent Anion Channel in Ischemia [PDF]

Biophysical Journal, 2012
Ischemia is characterized by the inhibition of ATP production via oxidative phosphorylation due to oxygen deprivation, which leads to mitochondria depolarization. Impaired mitochondrial respiration involves the shift to an anaerobic metabolism and ionic imbalance that leads to a decrease of cytosolic pH and generation of reactive oxygen species (ROS ...
Teijido Hermida, Oscar, Bezrukov, Sergey M., Rostovtseva, Tatiana K.   +2 more
openaire   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina.

PLoS Biology, 2019
The stream of visual information sent from photoreceptors to second-order bipolar cells is intercepted by laterally interacting horizontal cells that generate feedback to optimize and improve the efficiency of signal transmission.
James C R Grove, Arlene A Hirano, Janira de Los Santos, Cyrus F McHugh, Shashvat Purohit, Greg D Field, Nicholas C Brecha, Steven Barnes   +7 more
doaj   +1 more source

Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo

Molecular Therapy: Nucleic Acids, 2014
Alterations in cellular metabolism and bioenergetics are vital for cancer cell growth and motility. Here, the role of the mitochondrial protein voltage-dependent anion channel (VDAC1), a master gatekeeper regulating the flux of metabolites and ions ...
Tasleem Arif, Lilia Vasilkovsky, Yael Refaely, Alexander Konson, Varda Shoshan-Barmatz   +4 more
doaj   +1 more source

Steering Oxygen Activation Pathways via Redox Dual‐Defects in 2D Hydrated WO3 for High‐Yield Singlet Oxygen Evolution

Advanced Functional Materials, EarlyView.
Redox dual‐defects (Cs substitution and O vacancies) in 2D hydrated WO3 steer O2 activation toward selective singlet oxygen evolution. WO‐CO achieves 8.6–15.8 times higher 1O2 production than single‐defect or pristine catalysts, enabling efficient pollutant mineralization via a pathway‐selective photocatalytic mechanism.
Sheng‐Qi Guo, Mingqi Xiao, Fangyuan Zhang, Hui Li, Yuli Jia, Zhenfang Zhang, Liqun Ye, Bo Yang, Tianyi Ma   +8 more
wiley   +1 more source

Voltage-dependent anion channels: different isoforms for different functions

, 2009
The Voltage-dependent anion channel (VDAC) is the most abundant protein of the outer mitochondrial membrane (OMM) and mediates the flow of ions and metabolites between the cytoplasm and the mitochondrial network.
DE STEFANI, Diego, De Stefani, D.
core  

Engineering MnNiPx Cathode via Dual Role of Mn: Simultaneous Enhancement of Activity and Intermittent Operation Durability

Advanced Functional Materials, EarlyView.
Engineering MnNiPx cathodes through the dual role of Mn simultaneously improves hydrogen evolution reaction activity and intermittent‐operation durability. Mn preferentially oxidizes to protect Ni–P sites from irreversible oxidation, while metallic Mn incorporation enhances the HER kinetics of Ni–P active layer.
Ik‐Sun Kim, Jungwoo Choi, Sechan Lee, Jung Eun Park, Changsoo Lee, Jongsu Seo, Ji Hee Kwon, Gisu Doo, Hyeonjung Park, Dongju Lee, Won‐Chul Cho, Changhee Kim, Nosang Vincent Myung, Sang Soo Han, Byeong‐Seon An, MinJoong Kim, Hyun‐Seok Cho   +16 more
wiley   +1 more source

Recombinant Human Voltage Dependent Anion Selective Channel Isoform 3 (hVDAC3) Forms Pores with a Very Small Conductance

Cellular Physiology and Biochemistry, 2014
Background/Aims: Voltage-dependent anion channels (VDAC), also known as eukaryotic porins, are located in the outer mitochondrial membrane and allow the flux of ions and small metabolites. While the pore-forming ability of recombinant VDAC1 and VDAC2 has
Vanessa Checchetto, Simona Reina, Andrea Magrì, Ildikò Szabo, Vito De Pinto   +4 more
doaj   +1 more source

Coupling Anodic Activity and Stability at Ni‐Based Non‐Oxide Catalysts via Coordinating Alcohol Oxidation and Oxygen Evolution

Advanced Functional Materials, EarlyView.
A cooperative and competitive interrelationship between alcohol oxidation (AOR) and water oxidation (OER) was observed on a typical anode catalyst of Ni2P. In situ Raman spectroscopy and electrochemical analyses revealed a specific complementary mechanism between them, in which OER and AOR critically contribute to the activity and stability of anodic ...
Yong Yan, Xinyu Liu, Yuguo Zhao, Hanwen Jian, Huan Zhou, Riyi Zhang, Dong Wang, Peter Schaaf, Lihua Wang, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source