Results 71 to 80 of about 33,802 (280)

Alpha-Synuclein and Mitochondrial Dysfunction in Parkinson’s Disease: The Emerging Role of VDAC

Biomolecules, 2021
Alpha-Synuclein (αSyn) is a protein whose function is still debated, as well as its role in modulation of mitochondrial function in both physiological and pathological conditions.
Pierpaolo Risiglione, Federica Zinghirino, Maria Carmela Di Rosa, Andrea Magrì, Angela Messina   +4 more
doaj   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. [PDF]

PLoS ONE, 2011
Tubulin was recently found to be a uniquely potent regulator of the voltage-dependent anion channel (VDAC), the most abundant channel of the mitochondrial outer membrane, which constitutes a major pathway for ATP/ADP and other metabolites across this ...
Kely L Sheldon, Eduardo N Maldonado, John J Lemasters, Tatiana K Rostovtseva, Sergey M Bezrukov   +4 more
doaj   +1 more source

Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer

Advanced Functional Materials, EarlyView.
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero, Meghna Jha, Elsa Veronica Flores‐Vela, Joost Kimpel, Andreas Schaefer, Jiali Guo, Jesika Asatryan, Alberto Peinador Veiga, Shuichi Haraguchi, Per‐Anders Carlsson, Jaime Martín, Mariano Campoy‐Quiles, Christian Müller   +12 more
wiley   +1 more source

Molecular Plasticity of the Human Voltage-Dependent Anion Channel Embedded Into a Membrane [PDF]

Structure, 2016
The voltage-dependent anion channel (VDAC) regulates the flux of metabolites and ions across the outer mitochondrial membrane. Regulation of ion flow involves conformational transitions in VDAC, but the nature of these changes has not been resolved to date.
Lin Ge, Saskia Villinger, Stefania A. Mari, Karin Giller, Christian Griesinger, Stefan Becker, Daniel J. Müller, Markus Zweckstetter   +7 more
openaire   +6 more sources

Over Expression of Voltage Dependent Anion Channel 2 (VDAC2) in Muscles of Electrically Stunned Chickens

International Islamic University Malaysia Engineering Journal, 2011
Water bath stunning is a common practice in commercial slaughterhouses. Such treatment is economic and in line with animal welfare practice. However, the conditions applied for the stunning process may vary from a slaughterhouse to another slaughterhouse.
Norshahida Abu Samah, Azura Amid, and Faridah Yusof
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

ER localized bestrophin1 activates Ca2+ dependent ion channels TMEM16A and SK4

, 2009
Bestrophins form Ca2+ activated Cl- channels and regulate intercellular Ca2+ signaling1. We demonstrate that bestrophin 1 is localized in the endoplasmic reticulum (ER), where it physically interacts with stromal interacting molecule 1 (Stim1), the ER ...
Rainer Schreiber, Fadi AlDehni, Kunzelmann, Karl, Ousingsawat, Jiraporn, René Barro-Soria, Karl Kunzelmann, Joana Almaça, Jiraporn Ousingsawat, Schreiber, Rainer, AlDehni, Fadi, Barro-Soria, René, Almaça, Joana, Ralph Witzgall, Witzgall, Ralph   +13 more
core   +2 more sources

Voltage-dependent anion channels 1 and 2 are expressed in porcine oocytes [PDF]

Bioscience Reports, 2009
The eukaryotic VDAC (voltage-dependent anion channel) is a pore-forming protein originally discovered in the outer membrane of mitochondria. It has been established as a key player in mitochondrial metabolism and ion signalling. In addition, in recent years, it has also been proposed that VDAC is present in extra-mitochondrial membranes, and it has ...
Cassará, María Carolina, Menzel, Viviana Andrea, Hinsch, Klaus-Dieter, Wrenzycki, Christine, Hinsch, Elvira   +4 more
openaire   +3 more sources

Structural basis for malate-driven, pore lipid-regulated activation of the Arabidopsis vacuolar anion channel ALMT9

Nature Communications
In plant cells, ALMTs are key plasma and vacuolar membrane-localized anion channels regulating plant responses to the environment. Vacuolar ALMTs control anion accumulation in plant cells and, in guard cells, they regulate stomata aperture.
Yeongmok Lee, Elsa Demes-Causse, Jaemin Yoo, Seo Young Jang, Seoyeon Jung, Justyna Jaślan, Geum-Sook Hwang, Jejoong Yoo, Alexis De Angeli, Sangho Lee   +9 more
doaj   +1 more source