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The voltage dependent anion selective channel family in Drosophila melanogaster.
The Italian journal of biochemistry, 2007VDACs (voltage-dependent anion-selective channels) or mitochondrial PORINS are transmembrane proteins forming pores in the outer membrane. In eukaryotic genomes multiple genes coding for VDAC homologues have been discovered, but the functional meaning of this gene redundancy is unknown. In Drosophila melanogasterthree additional genes homologous to the
GUARINO, FRANCESCA MARIA +8 more
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Transmembrane arrangement of mitochondrial porin or voltage-dependent anion channel (VDAC)
Journal of Bioenergetics and Biomembranes, 1992Porin or voltage-dependent anion-selective channel (VDAC) is the main protein responsible for the high permeability of the outer mitochondrial membrane. The mitochondrial porin is mainly composed of sided beta-strands, in analogy with bacterial porin, whose structure has been resolved at 1.8 A resolution.
DE PINTO, Vito Nicola, PALMIERI F.
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[Voltage-dependent anion channel and hematological malignancies].
Zhongguo shi yan xue ye xue za zhi, 2011Voltage-dependent anion channel(VDAC)is mainly located on the outer mitochondrial membrane. High-resolution atomic force microscopy topography shows an eye-shaped VDAC with 3.8 nm x 2.7 nm pore dimensions. New work suggests pore formation by the assembly of homo-oligomers and supramolecule of VDAC or hetero oligomers composed of VDAC and pro-apoptotic ...
Yan, Sun, Ye, Chen
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Function and Regulation of Mitochondrial Voltage-Dependent Anion Channel
2015The voltage-dependent anion channel (VDAC) is the major protein of the mitochondrial outer membrane (MOM). It is now generally accepted that this channel is responsible for most of the metabolite flux in and out of mitochondria. Small ions, adenine nucleotides such as ATP and ADP, and other water soluble mitochondrial respiratory substrates cross the ...
Tatiana K. Rostovtseva +1 more
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