Results 111 to 120 of about 13,998 (216)

Mitochondrial Outer Membrane Permeability Change and Hypersensitivity to Digitonin Early in Staurosporine-induced Apoptosis [PDF]

, 2003
We have shown here that the apoptosis inducer staurosporine causes an early decrease in the endogenous respiration rate in intact 143B.TK- cells. On the other hand, the activity of cytochrome c oxidase is unchanged for the first 8 h after staurosporine ...
Attardi, Giuseppe, Chomyn, Anne, Duan, Shili, Hájek, Petr, Lin, Catherine, Shin, Soo Kyung   +5 more
core  

Orientia tsutsugamushi Alters Mitochondrial Function and Selectively Associates with VDAC

Pathogens
Orientia tsutsugamushi is an obligate intracellular alphaproteobacterium and the causative agent of the potentially fatal rickettsiosis, scrub typhus. During infection, O.
Savannah E. Sanchez, Travis J. Chiarelli, John S. Billingsley, Richard T. Marconi, Jason A. Carlyon   +4 more
doaj   +1 more source

Ketamine effect on intracellular and mitochondrial calcium mobilization [PDF]

, 2016
The suppressive effects of ketamine on intracellular calcium has been reported in a variety of cells although the mechanisms involved are not well understood.
Bustamante, Jaunita, Czerniczyniec, Analia, Lores Arnaiz, Silvia   +2 more
core  

The mitochondrial translocator protein in human gliomas

, 2010
The translocator protein (TSPO) is an 18 kDa molecule spanning the outer mitochondrial membrane. Structural predictions, reported physical interactions and experimental data from diverse models suggest that TSPO is involved in apoptosis, proliferation ...
Janczar, Karolina, Janczar, Karolina
core   +1 more source

Voltage-Dependent Anion Channels in Male Reproductive Cells: Players in Healthy Fertility?

Biomolecules
Male infertility affects nearly 50% of infertile couples, with various underlying causes, including endocrine disorders, testicular defects, and environmental factors. Spermatozoa rely on mitochondrial oxidative metabolism for motility and fertilization,
Stefano Conti Nibali, Giuseppe Battiato, Xena Giada Pappalardo, Vito De Pinto   +3 more
doaj   +1 more source

Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis. [PDF]

, 2019
Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic disruption that may be therapeutically targetable. Among them, glucose metabolism and glycolytic intermediaries seem to have an important role in fibroblast-like ...
de Oliveira, Patricia Gnieslaw, Farinon, Mirian, Guma, Monica, Miyamoto, Shigeki, Sanchez-Lopez, Elsa   +4 more
core   +1 more source

Functional reassembly of membrane proteins in planar lipid bilayers [PDF]

, 2017
Recent progress in membrane biology has brought us to a stage where it is possible to associate complex biological processes to identifiable membrane proteins.
Darszon, A., Montal, M., Schindler, H.
core  

The small yeast GTPase Rho5 requires specific mitochondrial outer membrane proteins for translocation under oxidative stress and interacts with the VDAC Por1

European Journal of Cell Biology
Yeast Rho5 is a small GTPase which mediates the response to nutrient and oxidative stress, and triggers mitophagy and apoptosis. We here studied the rapid translocation of a GFP-tagged Rho5 to mitochondria under such stress conditions by live-cell ...
Linnet Bischof, Franziska Schweitzer, Hans-Peter Schmitz, Jürgen J. Heinisch   +3 more
doaj   +1 more source

ATP release via anion channels [PDF]

, 2005
Ravshan Z. Sabirov, Yasunobu Okada, G Burnstock, P Bodin, GR Dubyak, V Ralevic, RD Fields, T Forrester, RA North, K Sak, H Zimmermann, AD Conigrave, GR Dubyak, G Burnstock, JL Gordon, A Hazama, T Wijk Van der, G Arcuino, ML Cotrina, ML Cotrina, CE Stout, K Braet, S Eskandari, HZ Wang, RP Kondo, CC Naus, JR Riordan, WB Guggino, PM Quinton, DN Sheppard, MH Akabas, EM Schwiebert, HF Cantiello, EM Schwiebert, AG Prat, BM Rotoli, RS Sprague, AS Lader, AS Lader, D Reigada, IL Reisin, HF Cantiello, HF Cantiello, P Linsdell, B Illek, P Linsdell, MF Rosenberg, C Li, MM Reddy, R Grygorczyk, EH Abraham, EA Pasyk, M Sugita, GM Braunstein, Q Jiang, T Takahashi, R Grygorczyk, CH Mitchell, WC Watt, A Hazama, A Hazama, A Hazama, A Hazama, SH Donaldson, S Kawano, CF Higgins, P Borst, EH Abraham, I Bosch, Y Wang, RM Roman, RM Roman, EH Abraham, EH Abraham, MF Rosenberg, M Darby, K Strange, B Nilius, Y Okada, Y Okada, Y Okada, M Kubo, N Hagiwara, RT Worrell, PS Jackson, T Tsumura, RZ Sabirov, M Diaz, PS Jackson, M Oike, S Oiki, B Nilius, T Voets, T Voets, MR Shen, R Wondergem, S Mori, T Nabekura, Y Okada, E Maeno, Y Okada, Y Okada, T Shimizu, U Banderali, G Roy, IH Lambert, DB Shennan, A Stutzin, H Pasantes-Morales, B Nilius, G Droogmans, G Droogmans, VI Ternovsky, B Nilius, K Hisadome, GM Braunstein, RZ Sabirov, R Vennekens, Y Ando-Akatsuka, AL Blatz, W Schwarze, PT Gray, DJ Nelson, KH Woll, KH Woll, HA Coleman, XP Sun, XP Sun, A Saigusa, M Soejima, S Kokubun, A Coulombe, A Coulombe, AK Dutta, O Hurnak, O Hurnak, O Hurnak, J Zachar, O Hurnak, V Bolotina, LC Falke, N Hussy, L Bettendorff, L Bettendorff, JV Wu, PJ Forshaw, PJ Forshaw, M Diaz, MI Bahamonde, U Sonnhof, L Nowak, JG McLarnon, S Quasthoff, T Jalonen, R Dermietzel, B Guibert, JW Hanrahan, H Kajita, F Becq, M Duszyk, M Duszyk, L Vaca, RB Bajnath, AP Morris, GT Schneider, ME Krouse, PJ Kemp, C Garner, JM McGill, JM McGill, CH Mitchell, JJ Zhang, CW Do, HA Kolb, G Velasco, EM Schwiebert, EM Schwiebert, EM Schwiebert, DB Light, P Dietl, G Zhu, MJ O'Donnell, PD Bell, DC Marcus, PD Brown, G Riquelme, G Riquelme, G Riquelme, L Bernucci, M Henriquez, M Nobile, K Kawahara, SP Hardy, MI Bahamonde, SP Olesen, K Groschner, L Vaca, L Vaca, Z Li, FV McCann, FV McCann, MM Bosma, TH Yeh, MD Cahalan, LC Schlichter, PA Pahapill, HA Kolb, M Lindau, D Wohlrab, JH Ravesloot, A Stea, R Buettner, MJ O'Donnell, RZ Sabirov, AK Dutta, GD Hals, A Schmid, RJ Thompson, RZ Sabirov, DB Light, DB Light, K Dezaki, AP Feranchak, HT Fan, LG Navar, PD Bell, J Schnermann, PD Bell, JY Lapointe, S Hayashi, J Peti-Peterdi, T Forrester, AI Kuzmin, K Ugurbil, GV Born, LG Abood, H Darius, C Vial, MM Borst, T Katsuragi, JL Hall, H Ninomiya, AJ Vials, BM Paddle, T Forrester, MG Clemens, AI Kuzmin, HV Sparks Jr, G Vassort, G Burnstock, A Pelleg, GN Tseng, B Horowitz, M Tominaga, Y Liu, J Tranum-Jensen, C Steenbergen, RB Jennings, M Colombini, M Colombini, CA Mannella, FP Thinnes, C Jakob, J Eben-Brunnen, G Bathori, JI Moon, P Steinacker, C Schwarzer, S Shimizu, OV Krasilnikov, CM Carneiro, CM Carneiro, CA Mannella, TK Rostovtseva, T Rostovtseva, TK Rostovtseva, SF Okada, M Suzuki, SA John, V Valiunas, J Gualix, N Brustovetsky, N Brustovetsky, TJ Jentsch, R Dutzler, H Sigel, K Strange   +286 more
core   +1 more source

Oligomer-based functions of mitochondrial porin

Nature Communications
Porin, or the voltage-dependent anion channel (VDAC), is a primary β-barrel channel in the mitochondrial outer membrane. It transports small metabolites and ions through its β-barrel pore and plays key roles in apoptosis and inflammatory response.
Hironori Takeda, Saori Shinoda, Chiho Goto, Akihisa Tsutsumi, Haruka Sakaue, Chunming Zhang, Takashi Hirashima, Yuta Konishi, Haruka Ono, Yu Yamamori, Kentaro Tomii, Hiroya Shiino, Yasushi Tamura, Solène Zuttion, Bruno Senger, Sylvie Friant, Hubert D. Becker, Yuhei Araiso, Nanako Kobayashi, Noriyuki Kodera, Masahide Kikkawa, Toshiya Endo   +21 more
doaj   +1 more source