Results 111 to 120 of about 9,496 (202)

A comparative study of porin genes encoding VDAC, a voltage-dependent anion channel protein, in Anopheles gambiae and Drosophila melanogaster

, 2003
The protein called voltage-dependent anion selective channel (VDAC), or mitochondrial porin, forms channels that provide the major pathway for small metabolites across the mitochondrial outer membrane.
BARSANTI P, Marta Oliva, Corrado Caggese, CAGGESE C., Cecilia Lanave, SANTOLAMAZZA R, Roberta Moschetti, Gaetano Tripoli, CAIZZI, Ruggiero, Marco Sardiello, Paolo Barsanti, TRIPOLI G, SANTOLAMAZZA, FEDERICA, MOSCHETTI R, OLIVA, MARTA, LANAVE C, SARDIELLO M, Ruggiero Caizzi   +17 more
core   +1 more source

Antiseizure Medications Impact Mitochondrial Ion Channels via Novel Bioenergetic and Neural Mechanisms

Journal of Integrative Neuroscience
Antiseizure medications (ASMs) have traditionally been characterized by their modulation of neuronal ion channels and synaptic processes; however, accumulating evidence indicates that numerous ASMs also directly modulate mitochondrial function ...
Carmen Rubio, Norma Serrano-Garcia, Ricardo Pérez-Rubio, Javier Pérez-Villavicencio, Héctor Romo-Parra, Ángel Lee, Moisés Rubio-Osornio   +6 more
doaj   +1 more source

Oligomerization of the mitochondrial protein voltage-dependent anion channel is coupled to the induction of apoptosis

, 2010
Accumulating evidence implicates that the voltage-dependent anion channel (VDAC) functions in mitochon-drion-mediated apoptosis and as a critical player in the release of apoptogenic proteins, such as cytochrome c, triggering caspase activation and ...
Nurit Keinan, Dalia Tyomkin, Varda Shoshan-barmatz   +2 more
core   +1 more source

Tubulin tail sequences and post-translational modifications regulate closure of mitochondrial voltage-dependent anion channel (VDAC). [PDF]

J Biol Chem, 2015
Sheldon KL, Gurnev PA, Bezrukov SM, Sackett DL.   +3 more
europepmc   +1 more source

Expression of VDAC (Voltage-Dependent Anion Channel) isoforms in hematological cancers

, 2013
Voltage-Dependent Anion Channels (VDACs), also known as mitochondrial porins, are proteins located in the mitochondrial outer membrane (OMM). In humans there are three VDAC isoforms namely VDAC1, VDAC2 and VDAC3, encoded by three different genes with ...
Angela Messina, Vito DePinto, Nunzio Filardi, CUVIELLO, FLAVIA, Angela Amendola, SALVIA, ANTONELLA MARIA, Domenico Vertone, OSTUNI, Angela, BISACCIA, Faustino, Michele Cimminiello   +9 more
core  

Interaction of the human Voltage-Dependent Anion Channel 1 protein (VDAC-1) with Mycobacterium avium and its role in bacterial survival within phagocytic cells

M. avium is an opportunistic pathogen that primarily infects macrophages. In order to survive within the macrophage, M. avium secretes proteins into the host cell cytoplasm to inhibit specific functions such as phagosome acidification, altering pathways ...
Pham, Tuan
core   +1 more source

Andrographolide potentiates anti-tumor immunity in colorectal cancer (CRC) by targeting voltage-dependent anion channel (VDAC) and activating the cGAS-STING axis. [PDF]

J Gastrointest Oncol
Wu J, Li B, Chen Y, Zhang M, Li J, Dou G, Peng Y, Huang L, Zhou Y, Chen Z.   +9 more
europepmc   +1 more source

Voltage-dependent anion channels (VDAC) in the plasma membrane induce apoptosis

, 2006
Apoptosis, or programmed cell death, is essential for proper development and functioning of the body systems. During development, apoptosis plays a central role to sculpt the embryo, and in adults, to maintain tissue homeostasis by eliminating redundant, damaged or effete cells. Therefore, a tight regulation of this process is essential. Cell shrinkage
openaire   +1 more source

Genome-wide characterization and expression divergence of voltage-dependent anion channel (VDAC) in upland cotton (<i>Gossypium hirsutum</i> L.) in response to abiotic stresses. [PDF]

Front Plant Sci
Akram U, Ahmad A, Shah MN, Ahmad F, Baber M, Altaf MT, Rahman MAU, Albayrak Ö.   +7 more
europepmc   +1 more source

An interaction between Bcl-xL and the voltage-dependent anion channel (VDAC) promotes mitochondrial Ca2+ uptake. [PDF]

J Biol Chem, 2013
Huang H, Hu X, Eno CO, Zhao G, Li C, White C.   +5 more
europepmc   +1 more source