Results 101 to 110 of about 9,496 (202)

Voltage Dependence of Conformational Dynamics and Subconducting States of VDAC-1

, 2016
The voltage-dependent anion channel 1 (VDAC-1) is an important protein of the outer mitochondrial membrane that transports energy metabolites and is involved in apoptosis. The available structures of VDAC proteins show a wide β-stranded barrel pore, with
Giller, K., de Groot, Bert L., de Groot, B., Villinger, S., Mey, I., Lange, A., Paltrinieri, Licia, Zweckstetter, Markus, Becker, Stefan, Giller, Karin, Weichbrodt, C., Paltrinieri, L., Zweckstetter, M., Steinem, C., Villinger, Saskia, Becker, S., Weichbrodt, Conrad, Steinem, Claudia, Briones, R., Griesinger, C. ; https://orcid.org/, Mey, Ingo, Lange, Adam, Griesinger, Christian, Briones, Rodolfo   +23 more
core   +2 more sources

Functional dynamics in the voltage-dependent anion channel

, 2010
The voltage-dependent anion channel (VDAC), located in the outer mitochondrial membrane, acts as a gatekeeper for the entry and exit of mitochondrial metabolites.
Villinger, S., Zachariae, U., Zweckstetter, Markus, Zachariä, U., Adam Lange, Markus Zweckstetter, Villinger, Saskia, Zachariae, Ulrich; id_orcid, Becker, S., Zachariae, Ulrich, Briones, R., Saskia Villinger, Griesinger, Christian, Bert L. de Groot, Giller, K., Groot, Bert L. de, Rodolfo Briones, Stefan Becker, De Groot, B.L., de Groot, B., Karin Giller, Lange, A., Becker, Stefan, Giller, Karin, Zweckstetter, M., Griesinger, C., Christian Griesinger, Griesinger, C. ; https://orcid.org/, Ulrich Zachariae, de Groot, B. L., Lange, Adam, Briones, Rodolfo   +31 more
core   +2 more sources

Interaction of mitochondrial voltage-dependent anion channel from rat brain with plasminogen protein leads to partial closure of the channel

, 2004
Voltage-dependent anion channel (VDAC) is reported to be the receptor for plasminogen kringle5. In this paper, the interaction of VDAC from rat brain mitochondria with plasminogen protein has been investigated through bilayer electrophysiological studies.
Banerjee, Jyotirmoy, Ghosh, Subhendu
core   +1 more source

Voltage-Dependent Anion Channels in Male Reproductive Cells: Players in Healthy Fertility?

Biomolecules
Male infertility affects nearly 50% of infertile couples, with various underlying causes, including endocrine disorders, testicular defects, and environmental factors. Spermatozoa rely on mitochondrial oxidative metabolism for motility and fertilization,
Stefano Conti Nibali, Giuseppe Battiato, Xena Giada Pappalardo, Vito De Pinto   +3 more
doaj   +1 more source

Computational study of NADH interactions with voltage-dependent anion channel

, 2016
The Voltage Dependent Anion Channel (VDAC) is a mitochondrial outer mem- brane protein that serves as a diffusion pore for ions like Ca2+,Cl-, small metabolites and nucleotides like ATP, ADP and NADH, thereby regulating metabolic and energetic flux ...

core  

Zelluläre Protektion bei Transfektion mit Calciumphosphat/DNA-Nanopartikeln und durch Regulation des \(\textit {voltage-dependent anion channel-1}\) (VDAC-1)

, 2011
Eine erhöhte intrazelluläre freie Calcium-Ionen-Konzentration induziert den programmierten Zelltod, die Apoptose. In dieser Arbeit führte die Transfektion mit Calciumphosphat/DNA-Nanopartikeln nur zu einem geringen Anstieg der intrazellulären ...
Neumann, Sebastian (Dr. rer. nat.)
core  

The Voltage-Gating Process of the Voltage-Dependent Anion Channel Is Sensitive to Ion Flow

, 1998
The voltage-dependent anion channel (VDAC) is a voltage-gated channel from the mitochondrial outer membrane. It has two gating processes: one at positive potentials and the other at negative potentials.
Zizi, Martin, Byrd, Cynthia, Boxus, Roland, Colombini, Marco   +3 more
core   +1 more source

The small yeast GTPase Rho5 requires specific mitochondrial outer membrane proteins for translocation under oxidative stress and interacts with the VDAC Por1

European Journal of Cell Biology
Yeast Rho5 is a small GTPase which mediates the response to nutrient and oxidative stress, and triggers mitophagy and apoptosis. We here studied the rapid translocation of a GFP-tagged Rho5 to mitochondria under such stress conditions by live-cell ...
Linnet Bischof, Franziska Schweitzer, Hans-Peter Schmitz, Jürgen J. Heinisch   +3 more
doaj   +1 more source

Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage-dependent anion channel-1

, 2012
Peripheral benzodiazepine receptor (PBR) is a multifunctional protein mainly found on the outer mitochondrial membrane. PBR expression is increased by tumor necrosis factor-α (TNF-α) in endothelial cells.
Lee, Yu Ran, Lim, Sun Young, Park, Jin Bong, Ryoo, Sungwoo, Cho, Eun Jung, Park, Myoung Soo, Joo, Hee Kyoung, Jeon, Byeong Hwa, Lee, Eun Ji, Choi, Sunga   +9 more
core   +1 more source

Oligomer-based functions of mitochondrial porin

Nature Communications
Porin, or the voltage-dependent anion channel (VDAC), is a primary β-barrel channel in the mitochondrial outer membrane. It transports small metabolites and ions through its β-barrel pore and plays key roles in apoptosis and inflammatory response.
Hironori Takeda, Saori Shinoda, Chiho Goto, Akihisa Tsutsumi, Haruka Sakaue, Chunming Zhang, Takashi Hirashima, Yuta Konishi, Haruka Ono, Yu Yamamori, Kentaro Tomii, Hiroya Shiino, Yasushi Tamura, Solène Zuttion, Bruno Senger, Sylvie Friant, Hubert D. Becker, Yuhei Araiso, Nanako Kobayashi, Noriyuki Kodera, Masahide Kikkawa, Toshiya Endo   +21 more
doaj   +1 more source