Results 21 to 30 of about 63,537 (256)

Ion Channels of Pituitary Gonadotrophs and Their Roles in Signaling and Secretion

Frontiers in Endocrinology, 2017
Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete gonadotropins in response to elevation in intracellular calcium concentration.
Stanko S. Stojilkovic, Ivana Bjelobaba, Hana Zemkova   +2 more
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β Subunits of Voltage-Gated Calcium Channels [PDF]

Journal of Bioenergetics and Biomembranes, 2003
Calcium channel beta subunits have marked effects on the trafficking and on several of the biophysical properties of all high voltage activated calcium channels. In this article I shall review information on the different genes, on the structure of the beta subunits, and on their differential expression and post-translational modification.
openaire   +3 more sources

1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain

Molecular Brain, 2020
Chronic pain can be the result of an underlying disease or condition, medical treatment, inflammation, or injury. The number of persons experiencing this type of pain is substantial, affecting upwards of 50 million adults in the United States ...
Yuan Zhou, Song Cai, Kimberly Gomez, E. M. Kithsiri Wijeratne, Yingshi Ji, Shreya S. Bellampalli, Shizhen Luo, Aubin Moutal, A. A. Leslie Gunatilaka, Rajesh Khanna   +9 more
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Emerging roles of L-type voltage gated and other calcium channels in T lymphocytes.

Frontiers in Immunology, 2013
In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou, Mithilesh K. Jha, Didi eMatza, Richard A. Flavell, Richard A. Flavell   +4 more
doaj   +1 more source

RGK regulation of voltage-gated calcium channels [PDF]

Science China Life Sciences, 2015
Voltage-gated calcium channels (VGCCs) play critical roles in cardiac and skeletal muscle contractions, hormone and neurotransmitter release, as well as slower processes such as cell proliferation, differentiation, migration and death. Mutations in VGCCs lead to numerous cardiac, muscle and neurological disease, and their physiological function is ...
Buraei, Zafir, Lumen, Ellie, Kaur, Sukhjinder, Yang, Jian   +3 more
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Functional Coupling of Cav2.3 and BK Potassium Channels Regulates Action Potential Repolarization and Short-Term Plasticity in the Mouse Hippocampus

Frontiers in Cellular Neuroscience, 2019
Voltage-gated ion channels are essential for signal generation and propagation in neurons and other excitable cells. The high-voltage activated calcium-channel Cav2.3 is expressed throughout the central and peripheral nervous system, and within CA1 ...
Jakob J. Gutzmann, Lin Lin, Dax A. Hoffman   +2 more
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A Tale of Toxin Promiscuity: The Versatile Pharmacological Effects of Hcr 1b-2 Sea Anemone Peptide on Voltage-Gated Ion Channels

Marine Drugs, 2022
Sea anemones are a rich source of biologically active compounds. Among approximately 1100 species described so far, Heteractis crispa species, also known as sebae anemone, is native to the Indo-Pacific area.
Ernesto Lopes Pinheiro-Junior, Rimma Kalina, Irina Gladkikh, Elena Leychenko, Jan Tytgat, Steve Peigneur   +5 more
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Signaling complexes of voltage-gated calcium channels [PDF]

Channels, 2011
Voltage gated calcium channels are key mediators of depolarization induced calcium entry into electrically excitable cells. There is increasing evidence that voltage gated calcium channels, like many other types of ionic channels, do not operate in isolation, but instead forms signaling complexes with signaling molecules, G protein coupled receptors ...
Ray W, Turner, Dustin, Anderson, Gerald W, Zamponi   +2 more
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Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein

Stem Cell Reports, 2018
Summary: The absence of FMR1 protein (FMRP) causes fragile X syndrome (FXS) and disturbed FMRP function is implicated in several forms of human psychopathology.
Claudia Danesi, Venkat Swaroop Achuta, Padraic Corcoran, Ulla-Kaisa Peteri, Giorgio Turconi, Nobuaki Matsui, Ilyas Albayrak, Veronika Rezov, Anders Isaksson, Maija L. Castrén   +9 more
doaj   +1 more source

Photocontrol of Voltage-Gated Ion Channel Activity by Azobenzene Trimethylammonium Bromide in Neonatal Rat Cardiomyocytes. [PDF]

PLoS ONE, 2016
The ability of azobenzene trimethylammonium bromide (azoTAB) to sensitize cardiac tissue excitability to light was recently reported. The dark, thermally relaxed trans- isomer of azoTAB suppressed spontaneous activity and excitation propagation speed ...
Sheyda R Frolova, Olga Gaiko, Valeriya A Tsvelaya, Oleg Y Pimenov, Konstantin I Agladze   +4 more
doaj   +1 more source