A Non‐Invasive and DNA‐free Approach to Upregulate Mammalian Voltage‐Gated Calcium Channels and Neuronal Calcium Signaling via Terahertz Stimulation (Adv. Sci. 47/2024) [PDF]
Yuankun Sun +11 more
europepmc +3 more sources
A nongenomic mechanism for progesterone-mediated immunosuppression: Inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes [PDF]
The mechanism by which progesterone causes localized suppression of the immune response during pregnancy has remained elusive. Using human T lymphocytes and T cell lines, we show that progesterone, at concentrations found in the placenta, rapidly and ...
Beer +54 more
core +3 more sources
CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles
Activation of voltage-gated calcium channels at presynaptic terminals leads to local increases in calcium and the fusion of synaptic vesicles containing neurotransmitter.
Brian D Mueller +12 more
doaj +1 more source
Review the Regulation of Plasma Membrane Calcium Channel in Cancer and Patch Clamp Technique [PDF]
As one of the most versatile and universal second messengers, calcium plays an essential role in cell life. Here we briefly reviewed the research progress of how different calcium channels are located at the cell plasma membrane, including voltage-gated ...
Chen Nanjun, Fang Qigeng
doaj +1 more source
The Zoanthids are an order of cnidarians whose venoms and toxins have been poorly studied. Palythoa caribaeorum is a zoanthid commonly found around the Mexican coastline. In this study, we tested the activity of P.
Fernando Lazcano-Pérez +5 more
doaj +1 more source
Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology [PDF]
Voltage-gated calcium channels are essential players in many physiological processes in excitable cells. There are three main subdivisions of calcium channel, defined by the pore-forming α1 subunit, the CaV 1, CaV 2 and CaV 3 channels.
Dolphin, AC
core +1 more source
Nonspecific, Reversible Inhibition of Voltage-Gated Calcium Channels by CaMKII Inhibitor CK59 [PDF]
Investigation of kinase-related processes often uses pharmacological inhibition to reveal pathways in which kinases are involved. However, one concern about using such kinase inhibitors is their potential lack of specificity.
Kahrls, Andrew S., Mynlieff, Michelle
core +2 more sources
Ion Channels of Pituitary Gonadotrophs and Their Roles in Signaling and Secretion
Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete gonadotropins in response to elevation in intracellular calcium concentration.
Stanko S. Stojilkovic +2 more
doaj +1 more source
Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]
In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Chegini, S. +3 more
core +1 more source
LRRK2 Regulates Voltage-Gated Calcium Channel Function [PDF]
Voltage-gated Ca(2+) (CaV) channels enable Ca(2+) influx in response to membrane depolarization. CaV2.1 channels are localized to the presynaptic membrane of many types of neurons where they are involved in triggering neurotransmitter release. Several signaling proteins have been identified as important CaV2.1 regulators including protein kinases, G ...
Bedford, Cade +4 more
openaire +3 more sources

