Results 1 to 10 of about 402,017 (293)
Genetic epilepsy with febrile seizures plus – an overview [PDF]
Romanian Journal of Neurology, 2021 Genetic epilepsy with febrile seizures plus (GEFS+) is characterized by a group of genetic epilepsies associated predominately with an autosomal dominant pattern, but also with de novo and autosomal-recessive inheritance, these last two found in a small ...
Madalina Radu +3 more
doaj +1 more source
Voltage-Gated Ion Channels [PDF]
IEEE Transactions on Nanobioscience, 2005 Voltage-dependent ion channels are membrane proteins that conduct ions at high rates regulated by the voltage across the membrane. They play a fundamental role in the generation and propagation of the nerve impulse and in cell homeostasis. The voltage sensor is a region of the protein bearing charged amino acids that relocate upon changes in the ...
Sands, Z, Grottesi, A, Sansom, MS
openaire +4 more sources
The role of Phe150 in human voltage-gated proton channel
iScience, 2022 Summary: The voltage-gated proton channel Hv1 is a member of voltage-gated ion channels containing voltage-sensing domains (VSDs). The VSDs are made of four membrane-spanning segments (S1 through S4), and their function is to detect changes in membrane ...
Xin Wu, Lu Zhang, Liang Hong
doaj +1 more source
Functional reconstitution of a voltage-gated potassium channel in giant unilamellar vesicles. [PDF]
PLoS ONE, 2011 Voltage-gated ion channels are key players in cellular excitability. Recent studies suggest that their behavior can depend strongly on the membrane lipid composition and physical state. In vivo studies of membrane/channel and channel/channel interactions
Sophie Aimon +5 more
doaj +1 more source
Voltage Gated Lipid Ion Channels [PDF]
Biophysical Journal, 2013 10 pages, 7 figures - Strongly revised version compared to first version.
Blicher, Andreas +1 more
openaire +7 more sources
Advances in CaV1.1 gating: New insights into permeation and voltage-sensing mechanisms
Channels, 2023 The CaV1.1 voltage-gated Ca2+ channel carries L-type Ca2+ current and is the voltage-sensor for excitation-contraction (EC) coupling in skeletal muscle.
Hugo Bibollet +3 more
doaj +1 more source
Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel
Nature Communications, 2023 Human Eag2 is a voltage-gated potassium channel with unique delayed rectifying gating kinetics. Here, authors show how voltage opens the channel and illuminate a mechanism of delayed rectifier gating.
Mingfeng Zhang +2 more
doaj +1 more source
Executive Privilege in the Federal Courts [PDF]
, 1962 Apoptosis is one type of programmed cell death, important during tissue development and to maintain the tissue homeostasis. Apoptosis comprises a complex network of internal signaling pathways, and an important part of this signaling network is the ...
null null, Ulrika Englund
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Voltage-gated proton channels [PDF]
Cellular and Molecular Life Sciences, 2008 Voltage-gated proton channels, HV1, have vaulted from the realm of the esoteric into the forefront of a central question facing ion channel biophysicists, namely, the mechanism by which voltage-dependent gating occurs. This transformation is the result of several factors.
openaire +3 more sources
A nongenomic mechanism for progesterone-mediated immunosuppression: Inhibition of K+ channels, Ca2+ signaling, and gene expression in T lymphocytes [PDF]
, 1998 The mechanism by which progesterone causes localized suppression of the immune response during pregnancy has remained elusive. Using human T lymphocytes and T cell lines, we show that progesterone, at concentrations found in the placenta, rapidly and ...
Beer +54 more
core +3 more sources