Results 21 to 30 of about 157,979 (315)
Frontiers in Cellular Neuroscience, 2018 Exploring the properties of action potentials is a crucial step toward a better understanding of the computational properties of single neurons and neural networks. The voltage-gated sodium channel is a key player in action potential generation.
Mara Almog +4 more
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The Kv10.1 voltage-gated ion channel modeling based on control system theory
Current Directions in Biomedical Engineering, 2022 In this paper, we present a control system theory based modeling approach for the voltage-gated ion-channel Kv10.1 at different temperatures. Kv10.1 is expressed in the central nervous system and the brain of healthy humans.
Lozanović Šajić Jasmina +2 more
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Voltage-Gated Calcium Channels [PDF]
Cold Spring Harbor Perspectives in Biology, 2010 Voltage-gated calcium (Ca(2+)) channels are key transducers of membrane potential changes into intracellular Ca(2+) transients that initiate many physiological events. There are ten members of the voltage-gated Ca(2+) channel family in mammals, and they serve distinct roles in cellular signal transduction.
openaire +2 more sources
Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells [PDF]
, 2014 The final published version can be found here: http://dx.doi.org/10.1073/pnas.1411390111M.C. is the recipient of a Bennett Fellowship from Leukaemia and Lymphoma Research (ref. 12002). M.A.B.
Gribben, John G. +25 more
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Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes
Marine Drugs, 2020 Recently, Conorfamide-Sr3 (CNF-Sr3) was isolated from the venom of Conus spurius and was demonstrated to have an inhibitory concentration-dependent effect on the Shaker K+ channel.
Estuardo López-Vera +4 more
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Role of the C-terminal domain in the structure and function of tetrameric sodium channels [PDF]
, 2013 Voltage-gated sodium channels have essential roles in electrical signalling. Prokaryotic sodium channels are tetramers consisting of transmembrane (TM) voltage-sensing and pore domains, and a cytoplasmic carboxy-terminal domain.
Clapham, D.E. +17 more
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Can the Thermodynamic Hodgkin-Huxley Model of Voltage-Dependent Conductance Extrapolate for Temperature? [PDF]
, 2014 Hodgkin and Huxley (H-H) fitted their model of voltage-dependent conductances to experimental data using empirical functions of voltage. The thermodynamic H-H model of voltage dependent conductances is more physically plausible, as it constrains and ...
Michael D. Forrest +2 more
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Voltage-gated proton channel in a dinoflagellate [PDF]
Proceedings of the National Academy of Sciences, 2011 Fogel and Hastings first hypothesized the existence of voltage-gated proton channels in 1972 in bioluminescent dinoflagellates, where they were thought to trigger the flash by activating luciferase. Proton channel genes were subsequently identified in human, mouse, and Ciona intestinalis , but their existence in ...
Susan M E, Smith +6 more
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SGK3 Sensitivity of Voltage Gated K+ Channel Kv1.5 (KCNA5)
Cellular Physiology and Biochemistry, 2016 Background: The serum & glucocorticoid inducible kinase isoform SGK3 is a powerful regulator of several transporters, ion channels and the Na+/K+ ATPase.
Musaab Ahmed +4 more
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Fenestropathy of Voltage-Gated Sodium Channels [PDF]
Frontiers in Pharmacology, 2022 Voltage-gated sodium channels (Nav) are responsible for the initiation and propagation of action potentials in excitable cells. From pain to heartbeat, these integral membrane proteins are the ignition stations for every sensation and action in human bodies.
Tamer M. Gamal El-Din +2 more
openaire +3 more sources