Results 11 to 20 of about 157,979 (315)

VKCDB: Voltage-gated potassium channel database

open access: yesBMC Bioinformatics, 2004
Background The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based component of the membrane potential and are thus central to many critical ...
Gallin Warren J, Li Bin
doaj   +3 more sources

Hysteresis in voltage-gated channels [PDF]

open access: yesChannels, 2016
Ion channels constitute a superfamily of membrane proteins found in all living creatures. Their activity allows fast translocation of ions across the plasma membrane down the ion's transmembrane electrochemical gradient, resulting in a difference in electrical potential across the plasma membrane, known as the membrane potential.
openaire   +2 more sources

KCNE1 and KCNE2 provide a checkpoint governing voltage-gated potassium channel α-subunit composition [PDF]

open access: yes, 2011
Voltage-gated potassium (Kv) currents generated by N-type α-subunit homotetramers inactivate rapidly because an N-terminal ball domain blocks the channel pore after activation.
Abbott, G.   +12 more
core   +1 more source

Activity of Palythoa caribaeorum Venom on Voltage-Gated Ion Channels in Mammalian Superior Cervical Ganglion Neurons

open access: yesToxins, 2016
The Zoanthids are an order of cnidarians whose venoms and toxins have been poorly studied. Palythoa caribaeorum is a zoanthid commonly found around the Mexican coastline. In this study, we tested the activity of P.
Fernando Lazcano-Pérez   +5 more
doaj   +1 more source

Optimized tight binding between the S1 segment and KCNE3 is required for the constitutively open nature of the KCNQ1-KCNE3 channel complex

open access: yeseLife, 2022
Tetrameric voltage-gated K+ channels have four identical voltage sensor domains, and they regulate channel gating. KCNQ1 (Kv7.1) is a voltage-gated K+ channel, and its auxiliary subunit KCNE proteins dramatically regulate its gating.
Go Kasuya, Koichi Nakajo
doaj   +1 more source

Voltage gating in porin channels [PDF]

open access: yesFEBS Letters, 1987
Data from experiments in which porin channels are reconstituted into planar bilayer membranes are reviewed for their relevance to porin channel gating in vivo. Contradictory evidence concerning voltage gating indicates that the different results may stem from the variety of purification techniques employed.
openaire   +2 more sources

Molecular mechanisms of the coupling of gating to voltage sensing in transmembrane proteins [PDF]

open access: yes, 2014
Voltage gated potassium ion (Kv) channels regulate action potentials of the nervous system by responding to changes in transmembrane voltage, enabling K+ transport across the membrane to restore cells to their resting potential.
Starek, Greg
core   +1 more source

Developmental changes in voltage-gated calcium channel α(2)δ-subunit expression in the canine dorsal root ganglion [PDF]

open access: yes, 2012
The voltage-gated calcium channel subunit (128 plays a fundamental role in propagation of excitatory signals associated with release of glutamate and neuropeptides substance P (SP) and calcitonin gene-related protein (CGRP).
K. Matiasek   +18 more
core   +1 more source

Non-silent story on synonymous sites in voltage-gated ion channel genes. [PDF]

open access: yesPLoS ONE, 2012
Synonymous mutations are usually referred to as "silent", but increasing evidence shows that they are not neutral in a wide range of organisms. We looked into the relationship between synonymous codon usage bias and residue importance of voltage-gated ...
Tong Zhou   +5 more
doaj   +1 more source

Voltage-gated proton channels [PDF]

open access: yesCellular and Molecular Life Sciences, 2008
Voltage-gated proton channels, HV1, have vaulted from the realm of the esoteric into the forefront of a central question facing ion channel biophysicists, namely, the mechanism by which voltage-dependent gating occurs. This transformation is the result of several factors.
openaire   +3 more sources

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