Results 21 to 30 of about 402,017 (293)

Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel [PDF]

, 2014
Arginine methylation is a novel post-translational modification within the voltage-gated ion channel superfamily, including the cardiac sodium channel, Naᵥ1.5.
Beltran-Alvarez, Pedro, Brugada, Ramon, Díaz-Hernández, Rubí, Feixas, Ferran, Osuna, Sílvia, Pagans, Sara   +5 more
core   +2 more sources

VKCDB: Voltage-gated potassium channel database

BMC Bioinformatics, 2004
Background The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based component of the membrane potential and are thus central to many critical ...
Gallin Warren J, Li Bin
doaj   +1 more source

Non-silent story on synonymous sites in voltage-gated ion channel genes. [PDF]

PLoS ONE, 2012
Synonymous mutations are usually referred to as "silent", but increasing evidence shows that they are not neutral in a wide range of organisms. We looked into the relationship between synonymous codon usage bias and residue importance of voltage-gated ...
Tong Zhou, Eun A Ko, Wanjun Gu, Inja Lim, Hyoweon Bang, Jae-Hong Ko   +5 more
doaj   +1 more source

Liability of a Surgeon for the Extension of an Authorized Operation [PDF]

, 1956
Polyunsaturated fatty acids modulate the voltage dependence of several voltage-gated ion channels, thereby being potent modifiers of cellular excitability.
Billman, Boland, Broomand, Broomand, Börjesson, Börjesson, Börjesson, Börjesson, Catterall, Clarke, DeCaen, DeCaen, Delemotte, Elinder, Elinder, Fredrik Elinder, Henrion, Hock, Hoshi, Hoshi, Hoshi, Imaizumi, Jensen, Kamb, Keynes, Long, McKay, McLennan, Moreno, Nina E. Ottosson, Papazian, Richieri, Sara I. Liin, Schmidt, Spector, Sun, Tao, Tigerholm, Vreugdenhil, Xiao, Xiao, Xu, Xu, Yang   +43 more
core   +2 more sources

Spontaneous current generation in gated nanostructures [PDF]

, 2004
We have observed an unusual dc current spontaneously generated in the conducting channel of a short-gated GaAs transistor. The magnitude and direction of this current critically depend upon the voltage applied to the gate. We propose that it is initiated
A. K Savchenko, Altshuler B. L., Bykov A. A., D. A Ritchie, D. W Horsell, Fal'ko V. I., Gantmakher V. F., Kop'ev P. S., Laiko E. I., Smith R. A., V. I Kozub, V. M Vinokur, Veselago V. G., Y. M Galperin   +13 more
core   +1 more source

Voltage-Gated Sodium Channels in Neocortical Pyramidal Neurons Display Cole-Moore Activation Kinetics

Frontiers in Cellular Neuroscience, 2018
Exploring the properties of action potentials is a crucial step toward a better understanding of the computational properties of single neurons and neural networks. The voltage-gated sodium channel is a key player in action potential generation.
Mara Almog, Tal Barkai, Angelika Lampert, Alon Korngreen, Alon Korngreen   +4 more
doaj   +1 more source

The Kv10.1 voltage-gated ion channel modeling based on control system theory

Current Directions in Biomedical Engineering, 2022
In this paper, we present a control system theory based modeling approach for the voltage-gated ion-channel Kv10.1 at different temperatures. Kv10.1 is expressed in the central nervous system and the brain of healthy humans.
Lozanović Šajić Jasmina, Langthaler Sonja, Baumgartner Christian   +2 more
doaj   +1 more source

Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes

Marine Drugs, 2020
Recently, Conorfamide-Sr3 (CNF-Sr3) was isolated from the venom of Conus spurius and was demonstrated to have an inhibitory concentration-dependent effect on the Shaker K+ channel.
Estuardo López-Vera, Luis Martínez-Hernández, Manuel B. Aguilar, Elisa Carrillo, Joanna Gajewiak   +4 more
doaj   +1 more source

An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids [PDF]

, 2015
We describe the identification in aphids of a unique heterodimeric voltage-gated sodium channel which has an atypical ion selectivity filter and, unusually for insect channels, is highly insensitive to tetrodotoxin.
Amey, Joanna S., Burton, Mark J., Davies, T.G. Emyr, Duce, Ian R., Field, Linda M., Mellor, Ian R., O'Reilly, Andrias O., Puinean, Alin M., Wallace, B.A., Williamson, Martin S.   +9 more
core   +1 more source

Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1

Science, 2018
Structures of voltage-gated sodium channels In “excitable” cells, like neurons and muscle cells, a difference in electrical potential is used to transmit signals across the cell membrane. This difference is regulated by opening or closing ion channels in
Xiaojing Pan, Zhangqiang Li, Qiang Zhou, Huaizong Shen, Kun Wu, Xiaoshuang Huang, Jiaofeng Chen, Juanrong Zhang, Xuechen Zhu, Jianlin Lei, Wei Xiong, Haipeng Gong, Bailong Xiao, N. Yan   +13 more
semanticscholar   +1 more source