Voltage-gated ion channels as novel regulators of epithelial ion transport in the osmoregulatory organs of insects. [PDF]
Front Insect SciDates J, Kolosov D.
europepmc +2 more sources
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Voltage-gated ion channels. [PDF]
Br J Pharmacol, 2017 The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
Alexander SP +11 more
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Structural dynamics determine voltage and pH gating in human voltage-gated proton channel
eLife, 2022 Voltage-gated proton (Hv) channels are standalone voltage sensors without separate ion conductive pores. They are gated by both voltage and transmembrane proton gradient (i.e., ∆pH), serving as acid extruders in most cells.
Shuo Han +7 more
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Ion channels as molecular targets of glioblastoma electrotherapy
Frontiers in Cellular Neuroscience, 2023 Therapies with weak, non-ionizing electromagnetic fields comprise FDA-approved treatments such as Tumor Treating Fields (TTFields) that are used for adjuvant therapy of glioblastoma.
Tayeb Abed +6 more
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Light-Induced Control of Voltage Gated Ion Channels [PDF]
, 2022 Voltage gated ion channels are transmembrane proteins responsible for the generation and propagation of action potentials in excitable cells. They are key targets in receptor pharmacology, since the simple actions of opening and closing their pore with ...
Shirin, Faraji +3 more
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Self-organized enhancement of conductivity in biological ion channels [PDF]
, 2013 We discuss an example of self-organization in a biological system. It arises from long-range ion–ion interactions, and it leads us to propose a new kind of enhanced conduction in ion channels.
Kaufman, Igor +9 more
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Glial-dependent clustering of voltage-gated ion channels in Drosophila precedes myelin formation
bioRxiv, 2023 Neuronal information conductance depends on transmission of action potentials. The conductance of action potentials is based on three physical parameters: The axial resistance of the axon, the axonal insulation by glial membranes, and the positioning of ...
Simone Rey +5 more
semanticscholar +1 more source
CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain. [PDF]
Neuronal Signal, 2018 Neuropathic pain represents a significant and mounting burden on patients and society at large. Management of neuropathic pain, however, is both intricate and challenging, exacerbated by the limited quantity and quality of clinically available treatments.
Chew LA, Khanna R.
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Frontiers in Cardiovascular Medicine, 2022 Brugada syndrome is an inherited cardiac channelopathy arising from mutations in voltage-gated cardiac sodium channels. Idiopathic epilepsy portrays a coalescent underlying pathophysiological mechanism pertaining to the premature excitation of neuronal ...
Hafiz Omer +8 more
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Historical Perspective of the Characterization of Conotoxins Targeting Voltage-Gated Sodium Channels
Marine Drugs, 2023 Marine toxins have potent actions on diverse sodium ion channels regulated by transmembrane voltage (voltage-gated ion channels) or by neurotransmitters (nicotinic acetylcholine receptor channels).
James R. Groome
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