Results 131 to 140 of about 2,245,116 (239)

Parametric Analysis of Spiking Neurons in 16 nm Fin Field‐Effect Transistor Technology

open access: yesAdvanced Intelligent Discovery, EarlyView.
Energy efficient computing has driven a shift toward brain‐inspired neuromorphic hardware. This study explores the design of three distinct silicon neuron topologies implemented in 16 nm fin field‐Effect transistor technology. While the Axon‐Hillock design achieves gigahertz throughput, its functional fragility persists. The Morris–Lecar model captures
Logan Larsh   +3 more
wiley   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu   +8 more
wiley   +1 more source

Artificial pore blocker acts specifically on voltage-gated potassium channel isoform KV1.6. [PDF]

open access: yesJ Biol Chem, 2022
Gigolaev AM   +10 more
europepmc   +1 more source

Biallelic PIGB Variants Cause Motor Neuropathy with Conduction Blocks and Peripheral Nerve Hyperexcitability

open access: yesAnnals of Neurology, EarlyView.
Objective Glycosylphosphatidylinositol (GPI)‐anchored proteins play critical roles in nervous system function. Pathogenic variants in genes involved in GPI‐anchor biosynthesis cause early‐onset multisystem disorders known as inherited GPI deficiencies. We describe a novel neuromuscular phenotype associated with PIGB deficiency.
Gorka Fernández‐Eulate   +34 more
wiley   +1 more source

A novel loss-of-function mutation of the voltage-gated potassium channel Kv10.2 involved in epilepsy and autism. [PDF]

open access: yesOrphanet J Rare Dis, 2022
Galán-Vidal J   +8 more
europepmc   +1 more source

Correction: Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel. [PDF]

open access: yesJ Biol Chem, 2022
Burton MJ   +18 more
europepmc   +1 more source

The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation. [PDF]

open access: yesCardiovasc Res, 2022
Immler R   +16 more
europepmc   +1 more source

Polymer‐Based Probabilistic Bits for Thermodynamic Computing

open access: yesAdvanced Physics Research, EarlyView.
Electropolymerized conjugated polymers function as intrinsic entropy sources for probabilistic computing. Thermally driven conformational fluctuations of pendant triphenylamine groups produce stochastic resistance dynamics that are transduced into voltage‐gated probabilistic bits following logistic transfer functions identical to those of stochastic ...
Stephen H. Foulger   +7 more
wiley   +1 more source

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