Results 11 to 20 of about 2,245,116 (239)

Structure and function of potassium and calcium channels [PDF]

open access: yes, 2005
In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
core   +9 more sources

KCNE1 and KCNE2 provide a checkpoint governing voltage-gated potassium channel α-subunit composition [PDF]

open access: yes, 2011
Voltage-gated potassium (Kv) currents generated by N-type α-subunit homotetramers inactivate rapidly because an N-terminal ball domain blocks the channel pore after activation.
Abbott, G.   +12 more
core   +1 more source

Molecular mechanisms of the coupling of gating to voltage sensing in transmembrane proteins [PDF]

open access: yes, 2014
Voltage gated potassium ion (Kv) channels regulate action potentials of the nervous system by responding to changes in transmembrane voltage, enabling K+ transport across the membrane to restore cells to their resting potential.
Starek, Greg
core   +1 more source

Panama: An Open-Source Educational App for Ion Channel Biophysics Simulation

open access: yesFrontiers in Neuroinformatics, 2022
This article describes an open-source educational software, called Panama, developed using R, that simulates the biophysics of voltage-gated ion channels.
Binita Rajbanshi, Anuj Guruacharya
doaj   +1 more source

The response of the tandem pore potassium channel TASK-3 (K2P9.1) to voltage : gating at the cytoplasmic mouth [PDF]

open access: yes, 2009
Although the tandem pore potassium channel TASK-3 is thought to open and shut at its selectivity filter in response to changes of extracellular pH, it is currently unknown whether the channel also shows gating at its inner, cytoplasmic mouth through ...
Feng, J. F.   +23 more
core   +1 more source

Activity of Palythoa caribaeorum Venom on Voltage-Gated Ion Channels in Mammalian Superior Cervical Ganglion Neurons

open access: yesToxins, 2016
The Zoanthids are an order of cnidarians whose venoms and toxins have been poorly studied. Palythoa caribaeorum is a zoanthid commonly found around the Mexican coastline. In this study, we tested the activity of P.
Fernando Lazcano-Pérez   +5 more
doaj   +1 more source

Pulmonary vasoconstrictor action of KCNQ potassium channel blockers [PDF]

open access: yes, 2006
KCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important physiological functions. Recent reports indicate that KCNQ channels may also be expressed in portal vein where they are suggested to influence ...
Joshi, Shreena   +2 more
core   +5 more sources

Calcium and Potassium Channels in Experimental Subarachnoid Hemorrhage and Transient Global Ischemia

open access: yesStroke Research and Treatment, 2012
Healthy cerebrovascular myocytes express members of several different ion channel families which regulate resting membrane potential, vascular diameter, and vascular tone and are involved in cerebral autoregulation.
Marcel A. Kamp   +4 more
doaj   +1 more source

Heterozygous Deletion of Epilepsy Gene KCNQ2 Has Negligible Effects on Learning and Memory

open access: yesFrontiers in Behavioral Neuroscience, 2022
Neuronal Kv7/Potassium Voltage-Gated Channel Subfamily Q (KCNQ) potassium channels underlie M-current that potently suppresses repetitive and burst firing of action potentials (APs).
Gregory C. Tracy   +7 more
doaj   +1 more source

Photocontrol of Voltage-Gated Ion Channel Activity by Azobenzene Trimethylammonium Bromide in Neonatal Rat Cardiomyocytes. [PDF]

open access: yesPLoS ONE, 2016
The ability of azobenzene trimethylammonium bromide (azoTAB) to sensitize cardiac tissue excitability to light was recently reported. The dark, thermally relaxed trans- isomer of azoTAB suppressed spontaneous activity and excitation propagation speed ...
Sheyda R Frolova   +4 more
doaj   +1 more source

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