Results 51 to 60 of about 101,918 (291)

Pulmonary vasoconstrictor action of KCNQ potassium channel blockers [PDF]

, 2006
KCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important physiological functions. Recent reports indicate that KCNQ channels may also be expressed in portal vein where they are suggested to influence ...
AM Evans, AM Gurney, BC Schroeder, C Lerche, DA Brown, H-S Wang, HL Pieniaszek, HS Wang, J Robbins, JA Lamas, JP Savineau, K Chootip, LH Clapp, LH Clapp, ME Schnee, N Tinel, PJ Barnes, S Ohya, S Teng, SY Yeung, T Inoue, TJ Jentsch, VJ Nickolson, W-P Yang   +23 more
core   +3 more sources

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Characterization of Expression of the KCNE Gene Family in Zebrafish, Danio rerio [PDF]

, 2011
The KCNE gene family codes for five transmembrane accessory proteins, minK related peptides or Mirps, involved in the modification of voltage-gated potassium (Kv) channels, K+ selective pores vital in the regulation of membrane potential and ...
Vernlund, Lauren
core   +1 more source

Molecular Studies of Voltage-gated Potassium Channels

Cold Spring Harbor Symposia on Quantitative Biology, 1990
The cloning and characterization of the voltage-activated Shaker potassium channel gene in Drosophila have led to the identification of structural elements involved in potassium channel gating. As found for the voltage-activated sodium channel, the S4 segment, located in the conserved core of the protein, plays a central role in voltage-dependent ...
E, Isacoff, D, Papazian, L, Timpe, Y N, Jan, L Y, Jan   +4 more
openaire   +2 more sources

Single Solid‐State Ion Channels as Potentiometric Nanosensors

Advanced Functional Materials, EarlyView.
Single gold nanopores functionalized with mixed self‐assembled monolayers act as solid‐state ion channels for direct, selective potentiometric sensing of inorganic ions (Ag⁺). The design overcomes key miniaturization barriers of conventional ion‐selective electrodes by combining low resistivity with suppressed loss of active components, enabling robust
Gergely T. Solymosi, Gyula Jágerszki, Levente Illés, Péter Fürjes, Róbert E. Gyurcsányi   +4 more
wiley   +1 more source

The mechanism by which potassium causes neurite retraction in lamprey descending neurons in cell culture [PDF]

, 2004
only availableSevere spinal cord injury (SCI) disrupts descending axons from reticulospinal (RS) neurons that project to the spinal cord. In most “higher” vertebrates, including humans, recovery is very minimal due to limited regeneration in the central ...
Le, MyChi, Marsh, Georgia, McClellan, Andrew, Ryna, Sarah, Shotts, Lindsay   +4 more
core  

Alkali Ion‐Incorporated HfO2 Dielectrics for Reconfigurable Neuromorphic Computing

Advanced Functional Materials, EarlyView.
This work presents an indium gallium zinc oxide (IGZO) transistor with an alkali cation‐integrated hafnium dioxide (HfO2) dielectric exhibiting synaptic behavior via ion retention. The solution‐based film fabrication strategy overcomes the limitations of atomic layer deposition (ALD) and precursor coating, enabling the control of synaptic retention ...
Seung Yeon Ki, In Cheol Kwak, Seonkwon Kim, Jihyun Kim, Dong Gue Roe, Se‐Jin Kim, Joohoon Kang, Jeong Ho Cho   +7 more
wiley   +1 more source

Genomic organization and chromosomal localization of the murine 2 P domain potassium channel gene Kcnk8: conservation of gene structure in 2 P domain potassium channels. [PDF]

, 2000
A 2 P domain potassium channel expressed in eye, lung, and stomach, Kcnk8, has recently been identified. To initiate further biochemical and genetic studies of this channel, we assembled the murine Kcnk8 cDNA sequence, characterized the genomic structure
Bockenhauer, D, Gallagher, PG, Goldstein, SA, Nimmakayalu, MA, Ward, DC   +4 more
core   +1 more source

Progress on role of ion channels of cardiac fibroblasts in fibrosis

Frontiers in Physiology, 2023
Cardiac fibrosis is defined as excessive deposition of extracellular matrix (ECM) in pathological conditions. Cardiac fibroblasts (CFs) activated by injury or inflammation differentiate into myofibroblasts (MFs) with secretory and contractile functions ...
Chenxv Xing, Limeng Bao, Weidong Li, Hongkun Fan   +3 more
doaj   +1 more source

Role of Voltage-gated Potassium Channels in Cancer

The Journal of Membrane Biology, 2005
Ion channels are being associated with a growing number of diseases including cancer. This overview summarizes data on voltage-gated potassium channels (VGKCs) that exhibit oncogenic properties: ether-à-go-go type 1 (Eag1). Normally, Eag1 is expressed almost exclusively in tissue of neural origin, but its ectopic expression leads to uncontrolled ...
Pardo, L., Contreras-Jurado, C., Zientkowska, M., Alves, F., Stühmer, W.   +4 more
openaire   +4 more sources