Results 51 to 60 of about 1,936,199 (178)
Kv2.1 voltage‐gated potassium channels in developmental perspective [PDF]
Developmental Dynamics, 2019 AbstractKv2.1 voltage‐gated potassium channels consist of two types of α‐subunits: (a) electrically‐active Kcnb1 α‐subunits and (b) silent or modulatory α‐subunits plus β‐subunits that, similar to silent α‐subunits, also regulate electrically‐active subunits. Voltage‐gated potassium channels were traditionally viewed, mainly by electrophysiologists, as
Justyna Jędrychowska, Vladimir Korzh
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Contribution of Axon Initial Segment Structure and Channels to Brain Pathology
Cells, 2023 Brain channelopathies are a group of neurological disorders that result from genetic mutations affecting ion channels in the brain. Ion channels are specialized proteins that play a crucial role in the electrical activity of nerve cells by controlling ...
Juan José Garrido
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The role of humoral autoimmunity in gastrointestinal neuromuscular diseases [PDF]
, 2010 PhDDysfunction of the gastrointestinal neuromuscular apparatus (including interstitial cells of Cajal) is presumed to underlie a heterogeneous group of disorders collectively termed gastrointestinal neuromuscular diseases (GINMDs).
Hubball, Andrew William
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Toxicon: X, 2023 Venoms from tarantulas contain low molecular weight vasodilatory compounds whose biological action is conceived as part of the envenomation strategy due to its propagative effects. However, some properties of venom-induced vasodilation do not match those
Luis Fernando Díaz-Peña +8 more
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Potassium channels in prostate and colonic cancer [PDF]
, 2007 Large conductance Ca2+-activated K+ channels in human prostate cancer The KCNMA1 gene encoding the alpha-subunit of BK channels is amplified and BK channel expression is enhanced in late-stage, metastatic and hormone-refractory human prostate cancer ...
Ousingsawat, Jiraporn
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Progress on role of ion channels of cardiac fibroblasts in fibrosis
Frontiers in Physiology, 2023 Cardiac fibrosis is defined as excessive deposition of extracellular matrix (ECM) in pathological conditions. Cardiac fibroblasts (CFs) activated by injury or inflammation differentiate into myofibroblasts (MFs) with secretory and contractile functions ...
Chenxv Xing +3 more
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voltage-gated potassium channel.png
, 2016 The protein family includes 5 members: MinK, MiRP (MinK-related peptides) 1, MiRP2, MiRP3 and MiRP4, encoded by KCNE 1-5 respectively. These proteins are small type I integral membrane proteins, which can associate with and regulate various voltage-gated
Thomas Hooper (2927814)
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Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels
Respiratory Research, 2000 Activity of voltage-gated potassium (Kv) channels controls membrane potential, which subsequently regulates cytoplasmic free calcium concentration ([Ca2+]cyt) in pulmonary artery smooth muscle cells (PASMCs). Acute hypoxia inhibits Kv channel function in
Yuan Jason, Sweeney Michèle
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Voltage‐gated potassium channels: from hyperexcitability to excitement [PDF]
FEBS Letters, 1999 The superfamily of voltage‐activated potassium channels may express structurally and functionally diverse voltage‐activated potassium channels in the nervous system. The roles of some voltage‐activated potassium channel types, e.g. rapidly inactivating (transiently active type) channels and muscarine sensitive muscarine sensitive channels, are ...
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Potential roles of voltage-gated ion channel disruption in Tuberous Sclerosis Complex
Frontiers in Molecular NeuroscienceTuberous Sclerosis Complex (TSC) is a lynchpin disorder, as it results in overactive mammalian target of rapamycin (mTOR) signaling, which has been implicated in a multitude of disease states.
Hailey X. Egido-Betancourt +2 more
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