Results 241 to 250 of about 2,526,088 (292)

Interactions of pyrethroids with the voltage-gated sodium channel

open access: yes, 2009
Davies, T. G. E., Williamson, M. S.
core  

Molecular assessment of voltage-gated sodium channel (VGSC) gene mutations in Rhipicephalus microplus from Guangxi, China. [PDF]

open access: yesParasit Vectors
Jiang N   +11 more
europepmc   +1 more source

Volatile anaesthetics modulate voltage-gated sodium channel function at a site critical for gating

open access: yes
Hollingworth D   +6 more
europepmc   +1 more source

Voltage-gated sodium channels

Current Opinion in Pharmacology, 2015
Voltage-gated sodium channels play a key role in the transmission of sensory information about the status of organs in the periphery. Sensory fibers contain a heterogeneous yet specific distribution of voltage-gated sodium channel isoforms. Major efforts by industry and academic groups are underway to develop medicines that interrupt inappropriate ...
Kevin, Kwong, Michael J, Carr
openaire   +3 more sources

A tamoxifen receptor within a voltage-gated sodium channel [PDF]

open access: yesMolecular Cell, 2021
Voltage-gated sodium channels are targets for many analgesic and antiepileptic drugs whose therapeutic mechanisms and binding sites have been well characterized.
David Hollingworth   +2 more
exaly   +3 more sources

Voltage-gated sodium channels

Current Opinion in Pharmacology, 2001
Increased knowledge of the molecular diversity of sodium channel alpha- and beta-subunits, and their distribution of expression have been highlights of the past year. The development of subtype-specific channel blockers remains elusive, but the discovery of selective inhibitors such as mu-conotoxins promises useful antagonists in the near future.
J N, Wood, M, Baker
openaire   +2 more sources

The pharmacology of voltage-gated sodium channel activators [PDF]

open access: yesNeuropharmacology, 2017
Toxins and venom components that target voltage-gated sodium (NaV) channels have evolved numerous times due to the importance of this class of ion channels in the normal physiological function of peripheral and central neurons as well as cardiac and skeletal muscle.
Irina Vetter   +2 more
exaly   +6 more sources

Voltage-Gated Sodium Channels and Hyperalgesia

Annual Review of Pharmacology and Toxicology, 2004
Physiological and pharmacological evidence both have demonstrated a critical role for voltage-gated sodium channels (VGSCs) in many types of chronic pain syndromes because these channels play a fundamental role in the excitability of neurons in the central and peripheral nervous systems. Alterations in function of these channels appear to be intimately
Josephine, Lai   +3 more
openaire   +2 more sources

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