Results 21 to 30 of about 521,614 (247)

Brain Structure and Function: Insights from Chemical Neuroanatomy

open access: yesLife, 2023
We present a brief historical and epistemological outline of investigations on the brain’s structure and functions. These investigations have mainly been based on the intermingling of chemical anatomy, new techniques in the field of microscopy and ...
Luigi F. Agnati   +4 more
doaj   +1 more source

Tuning synaptic transmission in the hippocampus by stress: The CRH system

open access: yesFrontiers in Cellular Neuroscience, 2012
To enhance survival, an organism needs to remember--and learn from--threatening or stressful events. This fact necessitates the presence of mechanisms by which stress can influence synaptic transmission in brain regions, such as hippocampus, that ...
Yuncai eChen   +3 more
doaj   +1 more source

Nitric Oxide Signaling in the Auditory Pathway

open access: yesFrontiers in Neural Circuits, 2021
Nitric oxide (NO) is of fundamental importance in regulating immune, cardiovascular, reproductive, neuromuscular, and nervous system function. It is rapidly synthesized and cannot be confined, it is highly reactive, so its lifetime is measured in seconds.
Conny Kopp-Scheinpflug, Ian D. Forsythe
doaj   +1 more source

Diverse in- and output polarities and high complexity of local synaptic and non-synaptic signalling within a chemically defined class of peptidergic Drosophila neurons

open access: yesFrontiers in Neural Circuits, 2013
Peptidergic neurons are not easily integrated into current connectomics concepts, since their peptide messages can be distributed via non-synaptic paracrine signalling or volume transmission.
Gergely eKarsai   +11 more
doaj   +1 more source

Volume Transmission in the Brain: Beyond the Synapse [PDF]

open access: yesThe Journal of Neuropsychiatry and Clinical Neurosciences, 2014
A better understanding of volume transmission is important in neuropsychiatry, as this is now believed to be a major mode of action for many neuroactive substances, including the modulatory neurotransmitters and many psychiatric medications.
Katherine H, Taber, Robin A, Hurley
openaire   +2 more sources

Extrasynaptic Neurotransmission Mediated by Exocytosis and Diffusive Release of Transmitter Substances

open access: yesFrontiers in Synaptic Neuroscience, 2018
This review article deals with the mechanisms of extrasynaptic release of transmitter substances, namely the release from the soma, axon and dendrites in the absence of postsynaptic counterparts.
Elaine Del-Bel, Francisco F. De-Miguel
doaj   +1 more source

The Neurobiology of Imagination: Possible Role of Interaction-Dominant Dynamics and Default Mode Network

open access: yesFrontiers in Psychology, 2013
This work aims at presenting some hypotheses about the potential neurobiological substrate of imagery and imagination. For the present purposes, we will define imagery as the production of mental images associated with previous percepts, and imagination ...
Luigi Francesco Agnati   +4 more
doaj   +1 more source

Volume Transmission–Mediated Encephalopathies [PDF]

open access: yesArchives of Neurology, 2012
There is strong evidence that the composition of cerebrospinal fluid (CSF) influences brain development, neurogenesis, and behavior. The bidirectional exchange of CSF and interstitial fluid (ISF) across the ependymal and pia-glial membranes is required for these phenomena to occur.
Hans-Peter, Hartung, Marcel, Dihné
openaire   +2 more sources

Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system

open access: yesFrontiers in Physiology, 2012
We review the evidence of exocytosis from extrasynaptic sites in the soma, dendrites and axonal varicosities of central and peripheral neurons of vertebrates and invertebrates, and how it may contribute to signaling in the nervous system.
Citlali eTrueta   +1 more
doaj   +1 more source

Selective WGA uptake in the hippocampus from the locus coeruleus of DBH-WGA transgenic mice

open access: yesFrontiers in Behavioral Neuroscience, 2012
We generated transgenic mice in which a transsynaptic tracer, wheat germ agglutinin (WGA), was specifically expressed in the locus coeruleus neurons under the control of the dopamine-β-hydroxylase gene promoter. WGA protein was produced in more than 95%
Susan G eWalling   +4 more
doaj   +1 more source

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