Results 211 to 220 of about 214,027 (378)

von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.

New England Journal of Medicine, 1998
M. Furlan, R. Robles, M. Galbusera, G. Remuzzi, P. Kyrle, B. Brenner, M. Krause, I. Scharrer, V. Aumann, U. Mittler, M. Solenthaler, B. Lämmle   +11 more
semanticscholar   +1 more source

Diagnostic Performance of Prothrombin Time and Activated Partial Thromboplastin Time in Children: A Service Evaluation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Coagulation screening, consisting of prothrombin time (PT) and activated partial prothrombin time (aPTT), is routinely performed in paediatrics to identify bleeding disorders or guide peri‐procedural management. We evaluated the trends in utilisation and diagnostic yield of PT and aPTT testing as part of coagulation screening in a ...
Gerard Gurumurthy, Mikias Lemma, Lianna Reynolds, John Grainger, Jecko Thachil   +4 more
wiley   +1 more source

Collagen-factor VIII/von Willebrand factor protein interaction [PDF]

, 1984
C. M. Kessler, CM Floyd, ME Rick, DM Krizek, SL Lee, HR Gralnick   +5 more
openalex   +1 more source

Proteome‐Guided Drug Target Discovery for Periodontitis

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background and Objective Periodontitis is a chronic inflammatory disease driven by immune dysfunction and microbial imbalance. This study aims to identify circulating druggable proteins causally linked to the disease. Materials and Methods We integrated proteomics data from deCODE genetics with periodontitis genome‐wide association studies ...
Zoheir Alayash, Sebastian‐Edgar Baumeister, Birte Holtfreter, Thomas Kocher, Hansjörg Baurecht, Benjamin Ehmke, Daniel Hagenfeld, Stefan Lars Reckelkamm, Michael Nolde   +8 more
wiley   +1 more source

Sialic acid prevents loss of large von Willebrand factor multimers by protecting against amino-terminal proteolytic cleavage [PDF]

, 1988
Scott D. Berkowitz, AB Federici
openalex   +1 more source

Characterising the Periodontal Granulation Tissue Using scRNAseq

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate the cellular composition and molecular mechanisms of periodontal granulation tissue formation using single‐cell RNA sequencing (scRNA‐seq), aiming to enhance the understanding of periodontal disease pathogenesis and identify potential targets for regenerative therapies.
Wentao Zhu, Kathy Fung, Pawan Dhami, Paul Sharpe, Jan Krivanek, Luigi Nibali, Cheng Zhang, Vitor C. M. Neves   +7 more
wiley   +1 more source

Intraindividual variability of von Willebrand factor and the need for repeated testing. [PDF]

Res Pract Thromb Haemost
Kirkeby MH, Højbjerg JA, Abildgaard AM, Larsen JB.   +3 more
europepmc   +1 more source

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]

, 2010
,, Goodship, Tim H J, Machin, Sam, Taylor, C Mark, Wigmore, Stephen J   +4 more
core   +1 more source

Sympathetic innervation of human cervical lymph nodes: A potential neuroimmunomodulatory target for the treatment of T‐cell‐driven autoimmune diseases like MS?

Journal of Anatomy, EarlyView.
Recent animal studies have shown that the sympathetic nervous system (SNS) prevents disease activity of EAE (Experimental autoimmune encephalomyelitis, animal model of Multiple Sclerosis [MS]), presumably through adrenergic activity in the deep cervical lymph nodes (DCLNs).
Christopher Kremer, Claire Mackaaij, Suzanne A. M. W. Verlinde‐Schellekens, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +4 more
wiley   +1 more source

Constitutive interaction between neutrophils and von Willebrand factor in peripheral blood. [PDF]

Sci Rep
Wan Y, Gao M, Zhu J, Mu Q, Pan Y, Chen Y, Yang T, Deng W.   +7 more
europepmc   +1 more source