Results 81 to 90 of about 39,685 (269)
Ion Activation Methods for Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
Scientific Reports, 2017 CVB3 is a common human pathogen to be highly lethal to newborns and causes viral myocarditis and pancreatitis in adults. However, there is no vaccine available for clinical use.
Xingmei Qi, S. Xiong
semanticscholar +1 more source
HA titers and Vp1 expression levels of JCV Vp1 cysteine point mutants in mammalian cells.
, 2013 (A) Schematic diagram of cysteine point mutant Vp1s. Each of the six cysteine residues in the 354-amino-acid JCV Vp1 is marked with a “C” for the WT Vp1 (WT), and the cysteine residue mutated into alanine is designated as “A” for each point mutant Vp1 ...
Harumi Kasamatsu (468971) +9 more
core +1 more source
PLoS Pathogens, 2011 The RNA-dependent RNA polymerase VP1 of infectious pancreatic necrosis virus (IPNV) is a single polypeptide responsible for both viral RNA transcription and genome replication.
Stephen C Graham +6 more
doaj +1 more source
Vaccines, 2020 Enterovirus 71 (EV71) is the major causative agent in hand, foot, and mouth disease (HFMD), and it mainly infects children worldwide. Despite the risk, there is no effective vaccine available for this disease.
Suhaili Mustafa +5 more
doaj +1 more source
Novel Naturally Occurring Mutations of Enterovirus 71 Associated With Disease Severity
Frontiers in Microbiology, 2021 Infection with the re-emerging enterovirus 71 (EV-A71) is associated with a wide range of disease severity, including herpangina, encephalitis, and cardiopulmonary failure. At present, there is no FDA-approved therapeutics for EV-A71. Early diagnosis for
Chih-Shin Chang +13 more
doaj +1 more source
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
Tubular structures contain VP1.
, 2012 PyV-infected 3T3 cells or PML−/− MEFs (MOI of 10–20 pfu/cell) at 32 hpi were frozen by high pressure and processed by cryo-substitution for immunoelectron microscopy.
Cedric Bouchet-Marquis (174001) +7 more
core +1 more source
A Molecular Approach Applied to Enteroviruses Surveillance in Northern Taiwan, 2008-2012.
PLoS ONE, 2016 Traditional methods for detection and serotyping of enterovirus infections are virus isolation and immunofluorescence assay (VI-IFA), which are labor-intensive and time-consuming.
Wan-Yu Chung +5 more
doaj +1 more source
Achieving Firm Ambidexterity Through Portfolio Management Meeting Conversations
Creativity and Innovation Management, EarlyView.ABSTRACT The ability to pursue exploration and exploitation simultaneously has been extensively examined within the ambidexterity framework in creativity and innovation research. However, whether and how firm portfolio management meetings enable ambidexterity has not yet been identified by analyzing managers' conversations during such sessions ...
Claus J. Varnes, John K. Christiansen
wiley +1 more source