Results 111 to 120 of about 45,419 (204)

Identification and Phylogenetic Characterisation of Novel Adeno‐Associated Virus Capsids in Non‐Human Primate Tissues

Cell Proliferation, Volume 59, Issue 5, May 2026.
AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu, Kai Xu, Yali Ding, Kailun Liu, Jing Liu, Zongren Hou, Rui Niu, Ning Yang, Hualing Qin, Baoyang Hu, Ying Zhang, Wei Li   +11 more
wiley   +1 more source

Evaluation of Growth Differentiation Factor 15 as an Early Biomarker of Anthracycline‐Induced Cardiotoxicity Using an Integrated PK/PD Model

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Doxorubicin (DOX) is an effective chemotherapeutic agent; however, its use is limited by dose‐dependent cardiotoxicity, which is challenging to detect early with current biomarkers such as NT‐proBNP. Growth differentiation factor‐15 (GDF15) has emerged as a promising cytokine associated with cardiovascular disease.
Mohamed S. Dabour, Anne H. Blaes, Pamala A. Jacobson, Mark N. Kirstein, Beshay N. Zordoky, Shen Cheng   +5 more
wiley   +1 more source

Isolation of a feline-derived feline panleukopenia virus with an A300P substitution in the VP2 protein and confirmation of its pathogenicity in dogs

Animal Diseases
Feline panleukopenia virus (FPV) is a single-stranded DNA virus that can infect cats and cause feline panleukopenia, which is a highly contagious and fatal disease in felines.
Jiakang Li, Jiajia Peng, Yue Zeng, Ying Wang, Luying Li, Yiran Cao, Longlong Cao, QingXiu Chen, Zijun Ye, Dengyuan Zhou, Shengbo Cao, Qiuyan Li   +11 more
doaj   +1 more source

Effect of silver nanoparticles on antibody response against recombinant VP2 protein of Infectious bursal disease virus

, 2023
7-16A strong humoral response against Infectious bursal disease virus (IBDV) in breeder chickens transfers protective maternal immunity in chicks, and protect them from the disease.
Kurkure, Nitin V., Tembhurne, Prabhakar A., Ingle, Vijay C., Chaudhari, Sandeep P., Awandkar, Sudhakar   +4 more
core   +1 more source

Identification of infectious bursal disease virus (IBDV) receptors through the use of recombinant capsid protein, VP2. [PDF]

, 2014
Master of Science in Biochemistry. University of KwaZulu-Natal. Durban, 2014.Infectious bursal disease virus (IBDV) is a non-enveloped Birnavirus which infects the immature antibody producing B-cells of the bursa of Fabricius in young chickens. The virus
Brien, Kayleen Fransiena.
core  

Indirect ELISA Using Multi-Antigenic Dominants of VP1, VP2, and VP3 Recombinant Protein to Detect Antibodies Against Senecavirus A in Pigs

Veterinary Sciences
Senecavirus A (SVA) is an emerging pathogen that poses a significant threat to the global swine industry. With the advent of SVA vaccines, there is a growing need to develop serological diagnostic methods for evaluating vaccine-induced immunity.
Zenglin Wang, Dexin Li, Yufang Li, Yunjing Zhang, Junhua Deng, Liying Hao, Kegong Tian, Xiangdong Li   +7 more
doaj   +1 more source

Chondroitin Sulfate N-acetylgalactosaminyltransferase-2 Contributes to the Replication of Infectious Bursal Disease Virus via Interaction with the Capsid Protein VP2

Viruses, 2015
Infectious bursal disease virus (IBDV) is a birnavirus that causes a highly contagious immunosuppressive disease in young chickens. The capsid protein VP2 of IBDV plays multiple roles in its life cycle. To more comprehensively understand the functions of
Lizhou Zhang, Xiangang Ren, Yuming Chen, Yulong Gao, Nian Wang, Zhen Lu, Li Gao, Liting Qin, Yongqiang Wang, Honglei Gao, Kai Li, Lili Jiang, Hongyu Cui, Changjun Liu, Yanping Zhang, Xiaole Qi, Xiaomei Wang   +16 more
doaj   +1 more source

Preparation of Monoclonal Antibodies Against VP2 Protein of Human Polyomaviruses

, 2013
Aim of this diploma thesis was to prepare two protein antigens and two monoclonal antibodies, all based on VP2 minor protein of human polyomaviruses BK virus and Merkel Cell Polyomavirus.
Vochyánová, Klára
core  

Chimeric Porcine Parvovirus VP2 Virus-like Particles with Epitopes of South African Serotype 2 Foot-and-Mouth Disease Virus Elicits Specific Humoral and Cellular Responses in Mice

Viruses
Southern Africa Territories 2 (SAT2) foot-and-mouth disease (FMD) has crossed long-standing regional boundaries in recent years and entered the Middle East. However, the existing vaccines offer poor cross-protection against the circulating strains in the
Qian Li, Xusheng Ma, Yaner Shen, Junfei Dai, Xiaofeng Nian, Xiaofen Shang, Jiao Chen, Ashenafi Kiros Wubshet, Jie Zhang, Haixue Zheng   +9 more
doaj   +1 more source

Structural protein VP2 of African horse sickness virus is not essential for virus replication in vitro

, 2017
The Reoviridae family consists of nonenveloped multilayered viruses with a double-stranded RNA genome consisting of 9 to 12 genome segments. The Orbivirus genus of the Reoviridae family contains African horse sickness virus (AHSV), bluetongue virus, and ...
van Gennip, René G.P., Potgieter, Christiaan A., van Rijn, Piet A., van de Water, Sandra G.P.   +3 more
core   +1 more source