Results 91 to 100 of about 6,531,738 (232)

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

Viral oncolysis that targets raf-1 signaling control of nuclear transport [PDF]

open access: yes, 2013
The central role of Raf protein kinase isoforms in human cancer demands specific anti-Raf therapeutic inhibitors. Parvoviruses are currently used in experimental cancer therapy due to their natural oncotropism and lytic life cycle.
Almendral, José M.   +5 more
core   +1 more source

An experimental subunit vaccine based on Bluetongue virus 4 VP2 protein fused to an antigen-presenting cells single chain antibody elicits cellular and humoral immune responses in cattle, guinea pigs and IFNAR(-/-) mice.

open access: yesVaccine, 2015
Bluetongue virus (BTV), the causative agent of bluetongue disease (BT) in domestic and wild ruminants, is worldwide distributed. A total of 27 serotypes have been described so far, and several outbreaks have been reported.
Danilo Legisa   +8 more
semanticscholar   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

Cloning and Expression of Vp2 Gene of Chicken Anemia Vurus Strain Cux-1 in Lactococcus Lactis Mg1363 [PDF]

open access: yes, 2001
In this study, the lactococcal plasmid vector pMG36e, was exploited for the cloning, replication and expression of a viral protein-2 (VP2) gene in the bacterial host, Lactococcus lactis strain MG1363.
Ahmat, Nurfilza
core  

Sero‐Epidemiology and Molecular Detection of Bluetongue Virus in Goats in Bangladesh

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
The first large‐scale study in Bangladesh confirmed bluetongue virus infection in goats through combined c‐ELISA and nested RT‐PCR approaches, revealing high seroprevalence and identifying key management‐related risk factors. ABSTRACT Background Bluetongue (BT) is an arthropod‐transmitted, non‐contagious viral disease of domestic ruminants caused by ...
Md Habibur Rahman   +5 more
wiley   +1 more source

Expression and Functional Characterization of Bluetongue Virus VP2 Protein: Role in Cell Entry [PDF]

open access: yesJournal of Virology, 1999
ABSTRACT Segment 2 of bluetongue virus (BTV) serotype 10, which encodes the outer capsid protein VP2, was tagged with the S-peptide fragment of RNase A and expressed by a recombinant baculovirus. The recombinant protein was subsequently purified to homogeneity by virtue of the S tag, and the oligomeric nature of the purified ...
S S, Hassan, P, Roy
openaire   +2 more sources

Bluetongue virus structure and assembly. [PDF]

open access: yes, 2017
Bluetongue virus (BTV) is an insect-vectored emerging pathogen of wild ruminants and livestock in many parts of the world. The virion particle is a complex structure of consecutive layers of protein surrounding a genome of ten double-stranded (ds) RNA ...
Roy, P
core   +2 more sources

Identification and Phylogenetic Characterisation of Novel Adeno‐Associated Virus Capsids in Non‐Human Primate Tissues

open access: yesCell Proliferation, Volume 59, Issue 5, May 2026.
AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu   +11 more
wiley   +1 more source

Advances in the Treatment of Sensorineural Hearing Loss: From Traditional Therapies to Stem Cell and Gene Therapies

open access: yesAdvanced Sensor Research, Volume 5, Issue 4, April 2026.
Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen   +3 more
wiley   +1 more source

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