Results 91 to 100 of about 45,419 (204)
The secondary structure of the PPV7-VP2 capsid protein obtained from Colombian isolates.
Secondary structure of the PPV7/Col/Antioquia 2015 VP2-capsid protein. Prediction was carried out with PSIPRED. (TIF)
Dario Mogollón (11846809) +4 more
core +2 more sources
JC Virus Minor Capsid Proteins Vp2 and Vp3 Are Essential for Virus Propagation [PDF]
ABSTRACT Virus-encoded capsid proteins play a major role in the life cycles of all viruses. The JC virus capsid is composed of 72 pentamers of the major capsid protein Vp1, with one of the minor coat proteins Vp2 or Vp3 in the center of each pentamer.
M L, Gasparovic, G V, Gee, W J, Atwood
openaire +2 more sources
Canine parvovirus infection resulted in acute fatal myocarditis in one‐day‐old German Shepherd puppies. Histopathology demonstrated lymphoplasmacytic myocarditis with intranuclear inclusion bodies, and PCR confirmed viral DNA in cardiac tissue. These findings indicate perinatal transmission and emphasise that CPV myocarditis remains a lethal threat to ...
Seyedhosein Jarolmasjed +5 more
wiley +1 more source
Infectious bursal disease (IBD), caused by the infectious bursal disease virus (IBDV), remains a major threat to global poultry production. The viral capsid protein VP2 is the primary protective antigen; however, conventional vaccines frequently provide ...
Yingying Sun +8 more
doaj +1 more source
The Viroporin Activity of the Minor Structural Proteins VP2 and VP3 Is Required for SV40 Propagation [PDF]
For nonenveloped viruses such as Simian Virus 40, the mechanism used to translocate viral components across membranes is poorly understood. Previous results indicated that the minor structural proteins, VP2 and VP3, might act as membrane proteins during infection. Here, purified VP2 and VP3 were found to form pores in host cell membranes.
Kristina M, Giorda +3 more
openaire +2 more sources
A Mechanistic Model of rAAV Production in Synthetic Cell Lines
ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan +5 more
wiley +1 more source
Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede +14 more
wiley +1 more source
Expression and Functional Characterization of Bluetongue Virus VP2 Protein: Role in Cell Entry [PDF]
ABSTRACT Segment 2 of bluetongue virus (BTV) serotype 10, which encodes the outer capsid protein VP2, was tagged with the S-peptide fragment of RNase A and expressed by a recombinant baculovirus. The recombinant protein was subsequently purified to homogeneity by virtue of the S tag, and the oligomeric nature of the purified ...
S S, Hassan, P, Roy
openaire +2 more sources
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Analysis of binding properties of VP2 protein of Human parvovirus B19 through in silico molecular docking [PDF]
Human parvovirus B19, a member of the Parvoviridae family, is a pathogen associated with a wide variety of diseases. Most commonly, it causes childhood rash erythema infectiosum, but in some cases more serious symptoms such as persistent arthropathy ...
Dibyabhaba Pradhan +7 more
core +1 more source

