Results 61 to 70 of about 3,402,285 (161)

Image_1_Interaction between the VP2 protein of deformed wing virus and host snapin protein and its effect on viral replication.PNG

, 2023
IntroductionDeformed wing virus (DWV) is one of the causative agents of colony collapse disorder. The structural protein of DWV plays a vital role in the process of viral invasion and host infection; however, there is limited research on DWV.Methods and ...
Sichao Huang (4031558), Mingxiao Ma (753846), Li Sun (4624), Yueyu Ma (14207360), Dongliang Fei (753842), Ming Li (91180)   +5 more
core   +1 more source

The first report of porcine parvovirus 7 (PPV7) in Colombia demonstrates the presence of variants associated with modifications at the level of the VP2-capsid protein.

PLoS ONE, 2021
There are a wide variety of porcine parvoviruses (PPVs) referred to as PPV1 to PPV7. The latter was discovered in 2016 and later reported in some countries in America, Asia, and Europe.
Diana S Vargas-Bermudez, Santiago Rendon-Marin, Julian Ruiz-Saenz, Dario Mogollón, Jairo Jaime   +4 more
doaj   +1 more source

Impact of PD‐1 Inhibitor Timing Relative to Locoregional Therapy on Outcomes in uHCC Treated With Lenvatinib‐Based Triple Therapy

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background and Aims The optimal sequencing of programmed cell death protein 1 (PD‐1) inhibitors relative to locoregional therapy (LRT) in unresectable hepatocellular carcinoma (uHCC) remains undefined. This study evaluated the impact of PD‐1 inhibitor timing on outcomes in patients receiving hepatic arterial infusion chemotherapy (HAIC) or ...
Jian He, Jian Chen, Bohua Yu, Fuqun Wei, Weifu Liu, Peishu Huang, Songhui Wu, Xiang You, Zhisheng Chen, Ziqi Lin, Wuhua Guo, Shaowu Zhuang, Yiping Chen, Zhongwu Chen   +13 more
wiley   +1 more source

Expression and purification of CPV-VP2 proteins.

, 2015
Protein detection using SDS-PAGE (a): lane 1, His-Sumo-VP2 (85 kDa); lane 2, VP2 protein (65 kDa). Identification of proteins using Western blot (b): lane 1, His-Sumo-VP2; lane 2, VP2 protein.
Ye Jin (286793), Xueping Yao (798842), Suizhong Cao (690484), Xia Feng (179439), Dan Yan (246385), Shiqi Sun (416734), Huichen Guo (665818), Bin Wang (30851)   +7 more
core   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, Volume 42, Issue 5, September/October 2026.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Precise delineation of radiation targets for thoracic tumors in the immunotherapy era: From immune mechanisms to clinical practice

Precision Radiation Oncology, Volume 10, Issue 3, Page 371-387, September 2026.
RT‐immunotherapy synergy for thoracic tumors relies on precise target delineation to protect immune components. IFI, reduced volumes, and optimized positioning minimize damage, while multimodal imaging, DL, PBT, and FLASH‐RT enhance control. These innovations shift RT to an immune‐centric model, improving lung and esophageal cancer outcomes.
Xiaoying Chen, Minxiao Yi, Yu Deng, Qian Shen   +3 more
wiley   +1 more source

Dual-Copy VP2 expressed with CTA1-DD in transgenic Eimeria acervulina confers partial protection against infectious bursal disease virus

Poultry Science
Infectious bursal disease (IBD), caused by the infectious bursal disease virus (IBDV), remains a major threat to global poultry production. The viral capsid protein VP2 is the primary protective antigen; however, conventional vaccines frequently provide ...
Yingying Sun, Sixin Zhang, Guangwen Yin, Zhili Hao, Yi Yan, Jingxia Suo, Xinming Tang, Xun Suo, Xianyong Liu   +8 more
doaj   +1 more source

Effect of a silencing suppressor gene towards the expression of VP2 protein of highly virulent infectious bursal disease virus in tobacco [PDF]

Journal of BioScience and Biotechnology, 2013
Gene silencing has been recognized as an important factor, which influence the expression of heterologous protein delivered via plant-viral based system.
Siti-Hasmah Mohtar, Hwei-San Loh, Festo Massawe, Abdul-Rahman Omar   +3 more
doaj  

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, Volume 13, Issue 44, 7 August 2026.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source