Results 101 to 110 of about 42,178 (200)

Polar orthogonal representations of real reductive algebraic groups

open access: yes, 2008
We prove that a polar orthogonal representation of a real reductive algebraic group has the same closed orbits as the isotropy representation of a pseudo-Riemannian symmetric space.
Geatti, Laura, Gorodski, Claudio
core   +2 more sources

Low and High Pressor Doses of Ang II Lead to Two Distinct Phenotypes of Hypertensive Heart Disease in Mice

open access: yesAPMIS, Volume 134, Issue 1, January 2026.
ABSTRACT Hypertension is a major contributor to cardiovascular diseases, being the most common comorbidity and the biggest risk factor in heart failure with preserved ejection fraction. Angiotensin II (Ang II) is a known hypertension and heart failure inducer in mice, but its role in the causality in phenotype development remains unclear.
Diana Törmä   +5 more
wiley   +1 more source

Identification of the 15FRFG domain in HIV-1 Gag p6 essential for Vpr packaging into the virion

open access: yesRetrovirology, 2004
The auxiliary regulatory protein Vpr of HIV-1 is packaged in the virion through interaction with the Gag C-terminal p6 domain. Virion packaging of Vpr is critical for Vpr to exert functions in the HIV-1 life cycle.
Zhu Henghu, Jian Heng, Zhao Ling-Jun
doaj   +1 more source

The Koszul complex of a moment map

open access: yes, 2013
Let $K\to U(V)$ be a unitary representation of the compact Lie group $K$. Then there is a canonical moment mapping $\rho\colon V\to\mathfrak k^*$. We have the Koszul complex ${\mathcal K}(\rho,\mathcal C^\infty(V))$ of the component functions $\rho_1,...,
Herbig, Hans-Christian   +1 more
core   +1 more source

Role of HIV-1 Vpr in AIDS pathogenesis: relevance and implications of intravirion, intracellular and free Vpr

open access: yesBiomedicine & Pharmacotherapy, 2003
Vpr, a 14-kDa, 96 amino acid protein, is conserved among the primate lentiviruses HIV-1, HIV-2 and Simian Immunodeficiency virus supporting the notion that it plays an important role in virus life cycle in vivo. Vpr appears to have several functions including cell cycle arrest at G2 stage, apoptosis, nuclear localization, nuclear import of the pre ...
Parithosh K, Tungaturthi   +8 more
openaire   +2 more sources

ALMA and VLA observations of recombination lines and continuum toward the Becklin-Neugebauer object in Orion

open access: yes, 2012
Compared to their centimeter-wavelength counterparts, millimeter recombination lines (RLs) are intrinsically brighter and are free of pressure broadening.
Galvan-Madrid, Roberto   +2 more
core   +1 more source

Human immunodeficiency virus type 1 Vpr polymorphisms associated with progressor and nonprogressor individuals alter Vpr-associated functions

open access: yesJournal of General Virology, 2014
Following infection with Human immunodeficiency virus 1 (HIV-1) there is a remarkable variation in virus replication and disease progression. Both host and viral factors have been implicated in the observed differences in disease status. Here, we focus on understanding the contribution of HIV-1 viral protein R (Vpr) by evaluating the disease-associated
Kevin, Hadi   +7 more
openaire   +2 more sources

Construction of a Prokaryotic Expression Vector harboring Two HIV-1 Accessory Genes

open access: yesMedical Laboratory Journal, 2021
Background and objectives: HIV-1 Nef and Vpr antigens have been described as suitable candidates for therapeutic HIV vaccine development. The aim of this study was to generate Nef-Vpr fusion gene construct and to clone the construct into pET-23a (+), a ...
Arash Nikyar   +3 more
doaj  

Illuminating the Role of Vpr in HIV Infection of Myeloid Cells

open access: yesFrontiers in Immunology, 2019
Vpr is a 14 kDa accessory protein conserved amongst extant primate lentiviruses that is required for virus replication in vivo. Although many functions have been attributed to Vpr, its primary role, and the function under selective pressure in vivo ...
Sarah Beth Nodder, Suryaram Gummuluru
doaj   +1 more source

Decentralized dynamic task allocation for UAVs with limited communication range

open access: yes, 2018
We present the Limited-range Online Routing Problem (LORP), which involves a team of Unmanned Aerial Vehicles (UAVs) with limited communication range that must autonomously coordinate to service task requests.
Cerquides, Jesus   +4 more
core  

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