Results 111 to 120 of about 42,178 (200)

Nearest-Neighbor Searching Under Uncertainty II

, 2016
Nearest-neighbor search, which returns the nearest neighbor of a query point in a set of points, is an important and widely studied problem in many fields, and it has wide range of applications.
Agarwal, Pankaj K., Aronov, Boris, Har-Peled, Sariel, Philips, Jeff M., Yi, Ke, Zhang, Wuzhou   +5 more
core   +1 more source

Vpr Enhances HIV-1 Env Processing and Virion Infectivity in Macrophages by Modulating TET2-Dependent IFITM3 Expression

mBio, 2019
HIV-1 Vpr enhances viral replication in human macrophages via multiple mechanisms that are not clearly defined. It does not affect HIV-1 virion production during the first round of infection.
Qi Wang, Lishan Su
doaj   +1 more source

Using a dual plasma process to produce cobalt--polypyrrole catalysts for the oxygen reduction reaction in fuel cells -- part I: characterisation of the catalytic activity and surface structure

, 2012
A new dual plasma coating process to produce platinum-free catalysts for the oxygen reduction reaction in a fuel cell is introduced. The catalysts thus produced were analysed with various methods.
Brüser, Volker, Kummer, Kurt, Quade, Antje, Vyalikh, Denis, Walter, Christian, Weltmann, Klaus-Dieter   +5 more
core   +1 more source

Evidence for Vpr-dependent HIV-1 Replication in Human CD4⁺ CEM.NKR T-Cells

Retrovirology, 2012
Background Vpr is exclusively expressed in primate lentiviruses and contributes to viral replication and disease progression in vivo. HIV-1 Vpr has two major activities in vitro: arrest of cell cycle in the G2 phase (G2 arrest), and enhancement of viral ...
Zhou Tao, Dang Ying, Baker Jacob J, Zhou Jiajun, Zheng Yong-Hui   +4 more
doaj   +1 more source

Anti-Vpr Activities of Heat Shock Protein 27

Molecular Medicine, 2007
HIV-1 Vpr plays a pivotal role in viral pathogenesis and is preferentially targeted by the host immune system. In this report, we demonstrate that a small heat shock protein, HSP27, exhibits Vpr-specific antiviral activity, as its expression is specifically responsive to vpr gene expression and increased levels of HSP27 inhibit Vpr-induced cell cycle ...
Dong, Liang, Zsigmond, Benko, Emmanuel, Agbottah, Michael, Bukrinsky, Richard Y, Zhao   +4 more
openaire   +2 more sources

HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD

Scientific Reports, 2017
HIV patients develop hepatic steatosis. We investigated hepatic steatosis in transgenic mice expressing the HIV-1 accessory protein Vpr (Vpr-Tg) in liver and adipose tissues, and WT mice infused with synthetic Vpr.
Neeti Agarwal, Dinakar Iyer, Chiara Gabbi, Pradip Saha, Sanjeet G. Patel, Qianxing Mo, Benny Chang, Biman Goswami, Ulrich Schubert, Jeffrey B. Kopp, Dorothy E. Lewis, Ashok Balasubramanyam   +11 more
doaj   +1 more source

Phoretic Motion of Spheroidal Particles Due To Self-Generated Solute Gradients

, 2010
We study theoretically the phoretic motion of a spheroidal particle, which generates solute gradients in the surrounding unbounded solvent via chemical reactions active on its surface in a cap-like region centered at one of the poles of the particle.
A. Ajdari, A. Erbe, A.B. Pawar, A.B. Pawar, F. Juelicher, F. Pomer, F.A. Morrison Jr., G. Rückner, G.R. Willmott, G.R. Willmott, H. Brenner, H.F. Bauer, J. Ralston, J.L. Anderson, J.L. Anderson, J.M. Catchmark, J.R. Howse, M. N. Popescu, M. Tasinkevych, M.C. Fair, M.N. Popescu, N. Bala Saidulu, R. Golestanian, R. Golestanian, R. Golestanian, R.F. Ismagilov, S. Dietrich, T. Ohta, W.E. Paxton, W.E. Paxton, W.E. Paxton   +30 more
core   +1 more source

HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages

Nature Communications
HIV-1 Vpr promotes efficient spread of HIV-1 from macrophages to T cells by transcriptionally downmodulating restriction factors that target HIV-1 Envelope protein (Env).
Maria C. Virgilio, Barkha Ramnani, Thomas Chen, W. Miguel Disbennett, Jay Lubow, Joshua D. Welch, Kathleen L. Collins   +6 more
doaj   +1 more source

Thrust modulation methods for a subsonic V/STOL aircraft [PDF]

Low speed wind tunnel tests were conducted to assess four methods for attaining thrust modulation for V/STOL aircraft. The four methods were: (1) fan speed change, (2) fan nozzle exit area change, (3) variable pitch rotor (VPR) fan, and (4) variable ...
Woollett, R. R.
core   +1 more source

A parallel implementation of a multisensor feature-based range-estimation method [PDF]

There are many proposed vision based methods to perform obstacle detection and avoidance for autonomous or semi-autonomous vehicles. All methods, however, will require very high processing rates to achieve real time performance.
Sridhar, Banavar, Suorsa, Raymond E.
core   +1 more source