Results 61 to 70 of about 42,178 (200)
Precision Radiation Oncology, EarlyView.This study retrospectively analyzed two types of respiratory phase CT and PET/CT images of 20 lung cancer patients. After DIR and functional grading, three lung function images were developed, and their correlations and differences were evaluated. Abstract Background Pulmonary ventilation–perfusion function plays a crucial role in both radiotherapy ...
Suyan Bi +4 more
wiley +1 more source
The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90. [PDF]
PLoS ONE, 2009 BACKGROUND: A hallmark of AIDS progression is a switch of cytokines from Th1 to Th2 in the plasma of patients. IL-12, a critical Th1 cytokine secreted by antigen presenting cells (APCs) is suppressed by Vpr, implicating it as an important virulence ...
Irina Tcherepanova +8 more
doaj +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
Small, EarlyView.The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A
Nature Communications, 2021 Vpr is a HIV-1 accessory virulence factor that also interacts with the human DNA repair protein hHR23A. Here, the authors present the structure of Vpr in complex with the C-terminal half of hHR23A comprising the XPC-binding and ubiquitin-associated ...
In-Ja L. Byeon +11 more
doaj +1 more source
Pemanfaatan Sisa Tanaman Sayuran sebagai Komponen Complete Feed Terfermentasi terhadap Urea Darah dan Retensi Nitrogen Domba [PDF]
, 2012 Vegetable plant residues (VPR) potential as a source of feed for ruminants.The study was conducted to the utilization of vegetable plant residues as a grassfor component complete feed fermentation on the blood urea and nitrogenretention in sheep.
Murniastuti, H. Y. (Hikmah) +2 more
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The McKinleys of Punch: Politics and the Press in Melbourne, 1870s to 1920s
Australian Journal of Politics &History, EarlyView.This article re‐examines the Melbourne Punch (1855–1925; known simply as Punch from 1900) as a political weapon in the cut‐and‐thrust of Victorian, local, and national politics, in the hands of its longest‐serving, but least‐known proprietor, Alexander McKinley (1848–1927).
Richard Scully
wiley +1 more source
Virology Journal, 2011 Background Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) is a virion-associated regulatory protein that functions at several points within the viral life cycle and has been shown to accumulate primarily in the nucleus and at the ...
Ferrucci Adriano +2 more
doaj +1 more source
Clinical Genetics, EarlyView.CRISPR activation of NEB in fibroblasts, followed by RNA‐sequencing, documents spliceogenic effects of a NEB intronic variant. The assay enabled variant reclassification as likely pathogenic, providing molecular diagnosis in fetuses with Arthrogryposis multiplex congenita 6.
Doriana Misceo +7 more
wiley +1 more source
PLoS Pathogens, 2021 Viruses have evolved means to manipulate the host's ubiquitin-proteasome system, in order to down-regulate antiviral host factors. The Vpx/Vpr family of lentiviral accessory proteins usurp the substrate receptor DCAF1 of host Cullin4-RING ligases (CRL4),
Sofia Banchenko +12 more
doaj +1 more source
Hegel's Implicit View on How to Solve the Problem of Poverty [PDF]
, 2001 Against those who argue that Hegel despaired of providing a solution to the problem of poverty, I argue, on the basis of key dialectical transitions in Hegel's Philosophy of Right, that he held at least the following: (1) that the chronic poverty endemic
Anderson, Joel
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