Results 81 to 90 of about 42,178 (200)
Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest. [PDF]
PLoS Pathogens, 2010 HIV-1 Viral protein R (Vpr) induces a cell cycle arrest at the G2/M phase by activating the ATR DNA damage/stress checkpoint. Recently, we and several other groups showed that Vpr performs this activity by recruiting the DDB1-CUL4A (VPRBP) E3 ubiquitin ...
Jean-Philippe Belzile +4 more
doaj +1 more source
Non-local Control of the Kondo Effect in a Double Quantum Dot-Quantum Wire Coupled System
, 2006 We have performed low-temperature transport measurements on a double quantum dot-quantum wire coupled device and demonstrated non-local control of the Kondo effect in one dot by manipulating the electronic spin states of the other.
H. Takayanagi +11 more
core +1 more source
Advanced Science, Volume 13, Issue 8, 9 February 2026.YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang +8 more
wiley +1 more source
Vpr and Its Cellular Interaction Partners: R We There Yet?
Cells, 2019 Vpr is a lentiviral accessory protein that is expressed late during the infection cycle and is packaged in significant quantities into virus particles through a specific interaction with the P6 domain of the viral Gag precursor.
Helena Fabryova, Klaus Strebel
doaj +1 more source
Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages
eLife, 2020 HIV-1 Vpr is necessary for maximal HIV infection and spread in macrophages. Evolutionary conservation of Vpr suggests an important yet poorly understood role for macrophages in HIV pathogenesis.
Jay Lubow +11 more
doaj +1 more source
Journal of Separation Science, Volume 49, Issue 2, February 2026.ABSTRACT Additive manufacturing is transforming how microfluidic devices are prototyped and fabricated. Among various 3D printing methods, stereolithography (SLA) has become a dominant technique for microfluidics due to its high resolution and design flexibility, with widespread use in lab‐on‐a‐chip applications.
Guillermo Ramirez‐Alvarado +3 more
wiley +1 more source
Anti-Vpr Activity of a Yeast Chaperone Protein [PDF]
Journal of Virology, 2004 ABSTRACT Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) exerts multiple effects on viral and host cellular activities during viral infection, including nuclear transport of the proviral integration complex, induction of cell cycle G 2 arrest, and cell death.
Zsigmond, Benko +15 more
openaire +2 more sources
, 1999 Both in atomic physics and in mesoscopic physics it is sometimes interesting to consider the energy time-dependence of a parametrically-driven chaotic system. We assume an Hamiltonian ${\cal H}(Q,P;x(t))$ where $x(t)=Vt$.
A. Bulgac +18 more
core +1 more source
Bayesian Inference via GeTex‐OTS Based Stochastic Synapse for Uncertainty‐Aware Medical Diagnostics
SmartMat, Volume 7, Issue 1, February 2026.This work reports a GeTex ovonic threshold switch integrated into a compact 1S1T1R stochastic synapse that directly realizes an MC‐Dropconnect Bayesian neural network. Tunable probabilistic switching enables uncertainty‐aware COVID‐19 diagnosis and MNIST recognition while remaining compatible with conventional 1T1R CIM architectures, highlighting a ...
Xinyu Wen +9 more
wiley +1 more source
HIV-1 Vpr Induces DNA Double-Strand Breaks [PDF]
Cancer Research, 2006 Abstract Recent observations imply that HIV-1 infection induces chromosomal DNA damage responses. However, the precise molecular mechanism and biological relevance are not fully understood. Here, we report that HIV-1 infection causes double-strand breaks in chromosomal DNA. We further found that Vpr, an accessory gene product of HIV-1,
Hiroaki, Tachiwana +7 more
openaire +2 more sources