Results 121 to 130 of about 48,453 (241)
Ebola vaccine R&D: Filling the knowledge gaps
, 2015 With an emphasis on systems analyses, the VSV-EBOVAC project harnesses state-of-the-art technologies that illuminate mechanisms behind the observed immunogenicity and reactogenicity of the rVSV-ZEBOV vaccine and ensures that such information is shared ...
Medaglini, Donata +12 more
core +1 more source
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Aggregate, Volume 7, Issue 6, June 2026.Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
Effect of DN-Rab expression on VSV infection.
, 2013 Cells were transfected with plasmids expressing DN- or wt-Rab-eGFP proteins and infected with rVSV-wt or influenza virus at 18 hours post-transfection. Cells were fixed, permeabilized and stained for VSV N protein or influenza NP at 8 hr post-infection. (
Michael A. Whitt (330754) +2 more
core +1 more source
Mitochondrial NADK2‐dependent NADPH controls tau oligomer uptake in human neurons
Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.Abstract INTRODUCTION Reduced brain energy metabolism, mitochondria dysfunction, and extracellular tau oligomer buildup characterize Alzheimer's disease (AD), but how these phenomena cooperatively promote neurodegeneration is poorly understood. We now report that tau oligomers (TauOs) pathologically coordinate mitochondrial metabolism with increased ...
Evelyn Pardo +10 more
wiley +1 more source
Molecular Therapy: OncologyTherapy-resistant ovarian cancers have a poor prognosis and novel effective treatment options are urgently needed. In this study, we evaluated the therapeutic efficacy of the oncolytic vesicular stomatitis virus (VSV) against a panel of patient-derived ...
Karen Geoffroy +4 more
doaj +1 more source
A Case Report on Meningitis Complicated by Acute Ischemic Stroke and Failed Thrombolysis
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Ischemic stroke is one of the rare but grave complications of meningitis with poor outcomes and long‐term sequelae, and the role of thrombolysis with infection‐related stroke remains uncertain. This case report documents a 52‐year‐old man presented with fever, headache, vomiting, and altered sensorium, and on examination he had neck rigidity ...
Sonam Dema, Dechen Choden, Sonam Wangmo
wiley +1 more source
Reply to Rubinstein: Is Lgr4 essential for VSV– and VSV-G–pseudotyped lentiviral vector entry to cells? [PDF]
Journal of Biological Chemistry, 2018 Na, Zhang, Bing, Du
openaire +2 more sources
Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein
, 2018 International audienceVesicular stomatitis virus (VSV) is an oncolytic rhabdovirus and its glycoprotein G is widely used to pseudotype other viruses for gene therapy. Low-density lipoprotein receptor (LDL-R) serves as a major entry receptor for VSV. Here
Nikolic, Jovan +10 more
core +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.ABSTRACT Extracellular vesicles (EVs) are central mediators of tumour‐stroma communication, yet the mechanisms governing their biogenesis and functional cargo remain poorly understood. Here, we identify CD133 (Prominin‐1), selectively expressed in basal‐like triple‐negative breast cancer (BL‐TNBC) cells, acts as a key organizer of EV production and ...
Mireia Gomez‐Duro +14 more
wiley +1 more source
Protein composition of VSV particle [23].
, 2013 Protein composition of VSV particle [23].
Kwang-il Lim (274718), John Yin (274721)
core +1 more source