Results 101 to 110 of about 72,933 (233)

Analysis of Somatic Mutations and Immunotherapy Biomarkers in Chinese Patients With Non‐Small Cell Lung Cancer During 2019–2024: A Retrospective Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Understanding genetic alterations in lung cancer remains challenging due to tumor heterogeneity and malignancy. This study aimed to investigate somatic variations and immune‐related biomarkers in Chinese patients with NSCLC.
Xiumei Liu, Weigong Chen, Chengqi Xin, Zexu Wang, Kaiyu Yi, Liang Wang, Jing Liu   +6 more
wiley   +1 more source

A vesicular stomatitis virus-based African swine fever vaccine prototype effectively induced robust immune responses in mice following a single-dose immunization

Frontiers in Microbiology
IntroductionAfrican swine fever (ASF) is a highly contagious hemorrhagic fever disease in pigs caused by African swine fever virus (ASFV). It is very difficult to control and prevent ASF outbreaks due to the absence of safe and effective vaccines ...
Yunyun Ma, Yunyun Ma, Junjun Shao, Wei Liu, Shandian Gao, Decai Peng, Chun Miao, Sicheng Yang, Zhuo Hou, Guangqing Zhou, Xuefeng Qi, Huiyun Chang   +11 more
doaj   +1 more source

Characterization of Pseudotype VSV Possessing HCV Envelope Proteins

Virology, 2001
The genome of hepatitis C virus (HCV) encodes two envelope glycoproteins (E1 and E2), which are thought to be responsible for receptor binding and membrane fusion resulting in virus penetration. To investigate cell surface determinants important for HCV infection, we used a recombinant vesicular stomatitis virus (VSV) in which the glycoprotein gene was
Matsuura, Yoshiharu, Tani, Hideki, Suzuki, Kensuke, Kimura-Someya, Tomomi, Suzuki, Ryosuke, Aizaki, Hideki, Ishii, Koji, Moriishi, Kohji, Robison, Clinton S., Whitt, Michael A., Miyamura, Tatsuo   +10 more
openaire   +2 more sources

Layered Seismic Anisotropy and Tectonics of the Anatolian Plate

Geophysical Research Letters, Volume 53, Issue 8, 28 April 2026.
Abstract Anatolian tectonics are associated with slab retreat in the west and gravitational potential energy and continental collision in the east, leading to westward motion of Anatolia relative to Eurasia, partially accommodated on the North and East Anatolian transform faults.
Chuanming Liu, Vera Schulte‐Pelkum, Thorsten W. Becker, Frederik Link, Lili Feng   +4 more
wiley   +1 more source

VSV-CHIKV activates antitumor immunity by inducing pyroptosis in a melanoma model

Discover Oncology
Melanoma is the most dangerous skin cancer due to its difficulty in treatment, high recurrence rate and metastatic ability. As a vector for oncolytic viruses (OVs), vesicular stomatitis virus (VSV) has been shown to be effective against malignant ...
Fan Wu, Ying Zhan, Siyu Wang, Xiaoke Wang, Min Hui, Jian Zhang, Jing Zhang, Hongxu Yang, Yingfeng Lei, Shibin Yu   +9 more
doaj   +1 more source

The Oncolytic Virus VSV-GP Is Effective against Malignant Melanoma

Viruses, 2018
Previously, we described VSV-GP, a modified version of the vesicular stomatitis virus, as a non-neurotoxic oncolytic virus that is effective for the treatment of malignant glioblastoma and ovarian cancer. Here, we evaluate the therapeutic efficacy of VSV-
Janine Kimpel, Carles Urbiola, Iris Koske, Reinhard Tober, Zoltan Banki, Guido Wollmann, Dorothee von Laer   +6 more
doaj   +1 more source

NSAID Treatment Suppresses VSV Propagation in Mouse CNS

Virology, 2000
Cyclooxygenase (COX) is the key enzyme in the conversion of arachidonic acid to prostaglandins. COX has two isoforms: COX-1, the constitutively expressed form, and COX-2, the inducible form. Prostaglandins are mediators of many critical physiological and inflammatory responses, but little is known about their roles during a viral infection in the ...
Chen, Nannan, Warner, Jennifer L., Reiss, Carol Shoshkes   +2 more
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, Volume 600, Issue 7, Page 1073-1087, April 2026.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Contact Lens with Moiré Patterns for High‐Precision Eye Tracking

Advanced Functional Materials, Volume 36, Issue 29, 9 April 2026.
This work presents a passive contact lens for high‐precision eye tracking, integrating a microscopic moiré grating label. The parallax‐induced shift of macroscopic moiré patterns enables angle measurement with 0.28° precision using a standard camera under ambient light.
Ilia M. Fradkin, Roman V. Kirtaev, Mikhail S. Mironov, Dmitriy V. Grudinin, Alexander A. Marchenko, Marina M. Chugunova, Valentin R. Solovei, Alexander V. Syuy, Andrey A. Vyshnevyy, Ilya P. Radko, Aleksey V. Arsenin, Valentyn S. Volkov   +11 more
wiley   +1 more source

Overexpression of Smac by an Armed Vesicular Stomatitis Virus Overcomes Tumor Resistance

Molecular Therapy: Oncolytics, 2019
Despite reports of successful clinical cases, many tumors appear to resist infection by oncolytic viruses (OVs). To circumvent this problem, an armed vesicular stomatitis virus was constructed by inserting a transgene to express Smac/DIABLO during virus ...
Weike Li, Ravi Chakra Turaga, Xin Li, Malvika Sharma, Zahra Enadi, Sydney Nicole Dunham Tompkins, Kyle Christian Hardy, Falguni Mishra, Jun Tsao, Zhi-ren Liu, Daping Fan, Ming Luo   +11 more
doaj   +1 more source