Results 111 to 120 of about 48,453 (241)
VirusesVesicular Stomatitis Virus (VSV) has emerged as a promising candidate for various clinical applications, including vaccine development, virus pseudotyping, and gene delivery. Its broad host range, ease of propagation, and lack of pre-existing immunity in
Alaa A. Abdelmageed +2 more
doaj +1 more source
Journal of Applied Clinical Medical Physics, Volume 27, Issue 6, June 2026.Abstract Background The rapid evolution of deep learning (DL), particularly the emergence of generative adversarial networks (GANs) has demonstrated strong potential for generating high‐resolution, voxel‐level dosimetric data. However, GAN‐based approaches have not yet been broadly applied to the generation of tissue‐specific dose voxel kernels (DVKs ...
Otieno Erick Kapis +3 more
wiley +1 more source
Shaping Ti3C2 MXene Nanospheres for Precision Near‐Infrared Photothermal Therapy
Advanced Functional Materials, Volume 36, Issue 46, 8 June 2026.In this study, we report producing spherical MXenes via fs laser fragmentation of Ti3C2 flakes in liquid medium. The nanoparticles demonstrated pronounced light absorption and high photothermal conversion efficiencies of 68% and 63% under heating with NIR‐I and NIR‐II lasers, respectively.
Julia S. Babkova +21 more
wiley +1 more source
Identifying novel antiviral defences against VSV and HIV-1
, 2019 Mammalian cells encode an arsenal of antiviral defences, which can be deployed following sensing of an invading pathogen. These cell autonomous defences are stimulated by interferon (IFN) signalling which activates the expression of interferon-stimulated
Aziz, Muhamad Afiq
core +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, Volume 13, Issue 35, 24 June 2026.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, Volume 13, Issue 35, 24 June 2026.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
SiRNA-mediated knockdown of DDX24 inhibits VSV replication.
, 2013 (A) Loss of mDDX24 affects VSV-luc replication in MEFs. MEFs transfected with ns, mDDX24 or RIG-I siRNA for 72 hours were infected by VSV-luc at M.O.I. = 0.1 or 1.
Zhe Ma (167751) +3 more
core +1 more source
Advanced Science, Volume 13, Issue 35, 24 June 2026.ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
T.p. vignette. Each of the 25 engraved ill. on the themes of wealth and charitable giving is preceded by a brief title and a Bible citation, and followed by an explanation in verse. The first 24 ill. are numbered in the plate, the last is unnumbered. The
Wierix, Jeronimus, 1553-1619. +1 more
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