Results 11 to 20 of about 43,668 (144)

γ-Aminobutyric acid promotes vesicular stomatitis virus infection in mouse macrophages [PDF]

Jichu yixue yu linchuang, 2023
Objective To investigate the effect and mechanism of metabolite γ-aminobutyric acid (GABA) on viral infection to RAW264.7 cell lines and mouse primary peritoneal macrophages. Methods RAW264.7 cell lines were treated with 0,10,30,50 and 70 mmol/L GABA for
ZHAO Lu, LIU Yang
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Vesicular Stomatitis Virus Elicits Early Transcriptome Response in Culicoides sonorensis Cells

Viruses, 2023
Viruses that are transmitted by arthropods, or arboviruses, have evolved to successfully navigate both the invertebrate and vertebrate hosts, including their immune systems. Biting midges transmit several arboviruses including vesicular stomatitis virus (
Stacey L. P. Scroggs, Edward J. Bird, David C. Molik, Dana Nayduch   +3 more
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Defective Interfering Genomes and the Full-Length Viral Genome Trigger RIG-I After Infection With Vesicular Stomatitis Virus in a Replication Dependent Manner

Frontiers in Immunology, 2021
Replication competent vesicular stomatitis virus (VSV) is the basis of a vaccine against Ebola and VSV strains are developed as oncolytic viruses. Both functions depend on the ability of VSV to induce adequate amounts of interferon-α/β.
Andreas Linder, Andreas Linder, Viktoria Bothe, Nicolas Linder, Paul Schwarzlmueller, Frank Dahlström, Christoph Bartenhagen, Martin Dugas, Dharmendra Pandey, Julia Thorn-Seshold, Julia Thorn-Seshold, Daniel F. R. Boehmer, Lars M. Koenig, Sebastian Kobold, Sebastian Kobold, Max Schnurr, Johannes Raedler, Giulia Spielmann, Hadi Karimzadeh, Hadi Karimzadeh, Andreas Schmidt, Stefan Endres, Stefan Endres, Simon Rothenfusser, Simon Rothenfusser   +24 more
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Recombinant adenovirus expressing vesicular stomatitis virus G proteins induce both humoral and cell-mediated immune responses in mice and goats

BMC Veterinary Research, 2021
Background Vesicular stomatitis (VS) is an acute, highly contagious and economically important zoonotic disease caused by the vesicular stomatitis virus (VSV).
Xiaojuan Xue, Zhaorong Yu, Hongyan Jin, Lin Liang, Jiayang Li, Xiaolu Li, Yong Wang, Shangjin Cui, Gang Li   +8 more
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Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells

Molecular Therapy: Oncolytics, 2021
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using established ...
Teddy E. Kim, Shelby Puckett, Kailong Zhang, Denise M. Herpai, David A. Ornelles, John N. Davis, Anthony N. van den Pol, Waldemar Debinski, Douglas S. Lyles   +8 more
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Oncolytic Virus with Attributes of Vesicular Stomatitis Virus and Measles Virus in Hepatobiliary and Pancreatic Cancers

Molecular Therapy: Oncolytics, 2020
Recombinant vesicular stomatitis virus (VSV)-fusion and hemagglutinin (FH) was developed by substituting the promiscuous VSV-G glycoprotein (G) gene in the backbone of VSV with genes encoding for the measles virus envelope proteins F and H. Hybrid VSV-FH
Bolni Marius Nagalo, Camilo Ayala Breton, Yumei Zhou, Mansi Arora, James M. Bogenberger, Oumar Barro, Michael B. Steele, Nathan J. Jenks, Alexander T. Baker, Dan G. Duda, Lewis Rowland Roberts, Stephen J. Russell, Kah Whye Peng, Mitesh J. Borad   +13 more
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Distinct VSV-based Nipah virus vaccines expressing either glycoprotein G or fusion protein F provide homologous and heterologous protection in a nonhuman primate modelResearch in context

EBioMedicine, 2023
Summary: Background: Nipah virus (NiV) causes recurrent outbreaks of lethal respiratory and neurological disease in Southeast Asia. The World Health Organization considers the development of an effective vaccine against NiV a priority.
Emmie de Wit, Friederike Feldmann, Jacqueline Cronin, Kerry Goldin, Reinaldo Mercado-Hernandez, Brandi N. Williamson, Kimberly Meade-White, Atsushi Okumura, Julie Callison, Sarah Weatherman, Rebecca Rosenke, Victoria A. Avanzato, Jamie Lovaglio, Dana P. Scott, Andrea Marzi, Heinz Feldmann   +15 more
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The Methyltransferase Region of Vesicular Stomatitis Virus L Polymerase Is a Target Site for Functional Intramolecular Insertion

Viruses, 2019
The L-protein of vesicular stomatitis virus (VSV) is a single-chain multi-domain RNA-dependent RNA polymerase. Previously reported attempts of intramolecular insertions of fluorescent proteins into the L-protein resulted in temperature-sensitive and ...
Emmanuel Heilmann, Janine Kimpel, Stephan Geley, Andreas Naschberger, Carles Urbiola, Tobias Nolden, Dorotheé von Laer, Guido Wollmann   +7 more
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Transmission and pathogenesis of vesicular stomatitis viruses

Brazilian Journal of Veterinary Pathology, 2009
Vesicular Stomatitis (VS) is caused by Vesicular stomatitis viruses (VSV), negative single stranded RNA arthropod-borne members of the Family Rhabdoviridae.
Janildo L. Reis Jr, Danny Mead, Luis L. Rodriguez, Corrie C Brown   +3 more
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Safety and immunogenicity of GamEvac-Combi, a heterologous VSV- and Ad5-vectored Ebola vaccine: An open phase I/II trial in healthy adults in Russia

Human Vaccines & Immunotherapeutics, 2017
Ebola hemorrhagic fever, also known as Ebola virus disease or EVD, is one of the most dangerous viral diseases in humans and animals. In this open-label, dose-escalation clinical trial, we assessed the safety, side effects, and immunogenicity of a novel,
I. V. Dolzhikova, O. V. Zubkova, A. I. Tukhvatulin, A. S. Dzharullaeva, N. M. Tukhvatulina, D. V. Shcheblyakov, M. M. Shmarov, E. A. Tokarskaya, Y. V. Simakova, D. A. Egorova, D. N. Scherbinin, I. L. Tutykhina, A. A. Lysenko, A. V. Kostarnoy, P. G. Gancheva, T. A. Ozharovskaya, B. V. Belugin, L. V. Kolobukhina, V. B. Pantyukhov, S. I. Syromyatnikova, I. V. Shatokhina, T. V. Sizikova, I. G. Rumyantseva, A. F. Andrus, N. V. Boyarskaya, A. N. Voytyuk, V. F. Babira, S. V. Volchikhina, D. A. Kutaev, A. N. Bel'skih, K. V. Zhdanov, S. M. Zakharenko, S. V. Borisevich, D. Y. Logunov, B. S. Naroditsky, A. L. Gintsburg   +35 more
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