Results 31 to 40 of about 48,453 (241)

Transmission and pathogenesis of vesicular stomatitis viruses

Brazilian Journal of Veterinary Pathology, 2009
Vesicular Stomatitis (VS) is caused by Vesicular stomatitis viruses (VSV), negative single stranded RNA arthropod-borne members of the Family Rhabdoviridae.
Janildo L. Reis Jr, Danny Mead, Luis L. Rodriguez, Corrie C Brown   +3 more
doaj   +1 more source

Oncolytic Recombinant Vesicular Stomatitis Virus (VSV) Is Nonpathogenic and Nontransmissible in Pigs, a Natural Host of VSV [PDF]

Human Gene Therapy Clinical Development, 2017
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Lauro, Velazquez-Salinas, Shruthi, Naik, Steven J, Pauszek, Kah-Whye, Peng, Stephen J, Russell, Luis L, Rodriguez   +5 more
openaire   +3 more sources

Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma. [PDF]

, 2010
The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC). Identifying key regulators in diverse transduction pathways that define
Enrico N. De Toni, Jennifer Altomonte, Roland M Schmid, Schneider, Günter, Schmid, Roland M., Rizzani Antonia, Thasler Wolfgang E., Ebert Oliver, Thasler, Wolfgang E., Schmid Roland M., Marozin, Sabrina, De Toni, Enrico N., Kato, Nobuyuki, Marozin Sabrina, Wolfgang E Thasler, Wolfgang E. Thasler, Enrico N De Toni, Altomonte, Jennifer, Alexandra Junger, De Toni Enrico N., Altomonte Jennifer, Ebert, Oliver, Günter Schneider, Oliver Ebert, Sabrina Marozin, Junger Alexandra, Kato Nobuyuki, Roland M. Schmid, Junger, Alexandra, Schneider Günter, Nobuyuki Kato, Rizzani, Antonia, Antonia Rizzani   +32 more
core   +1 more source

Safety and immunogenicity of GamEvac-Combi, a heterologous VSV- and Ad5-vectored Ebola vaccine: An open phase I/II trial in healthy adults in Russia

Human Vaccines & Immunotherapeutics, 2017
Ebola hemorrhagic fever, also known as Ebola virus disease or EVD, is one of the most dangerous viral diseases in humans and animals. In this open-label, dose-escalation clinical trial, we assessed the safety, side effects, and immunogenicity of a novel,
I. V. Dolzhikova, O. V. Zubkova, A. I. Tukhvatulin, A. S. Dzharullaeva, N. M. Tukhvatulina, D. V. Shcheblyakov, M. M. Shmarov, E. A. Tokarskaya, Y. V. Simakova, D. A. Egorova, D. N. Scherbinin, I. L. Tutykhina, A. A. Lysenko, A. V. Kostarnoy, P. G. Gancheva, T. A. Ozharovskaya, B. V. Belugin, L. V. Kolobukhina, V. B. Pantyukhov, S. I. Syromyatnikova, I. V. Shatokhina, T. V. Sizikova, I. G. Rumyantseva, A. F. Andrus, N. V. Boyarskaya, A. N. Voytyuk, V. F. Babira, S. V. Volchikhina, D. A. Kutaev, A. N. Bel'skih, K. V. Zhdanov, S. M. Zakharenko, S. V. Borisevich, D. Y. Logunov, B. S. Naroditsky, A. L. Gintsburg   +35 more
doaj   +1 more source

Vesicular stomatitis virus infection promotes immune evasion by preventing NKG2D-ligand surface expression.

PLoS ONE, 2011
Vesicular stomatitis virus (VSV) has recently gained attention for its oncolytic ability in cancer treatment. Initially, we hypothesized that VSV infection could increase immune recognition of cancer cells through induction of the immune stimulatory ...
Helle Jensen, Lars Andresen, Jens Nielsen, Jan Pravsgaard Christensen, Søren Skov   +4 more
doaj   +1 more source

Infection of WDR81-deficient cells by VSV (GFP) or VSV-EBO GP (GFP).

, 2022
(A and B) Induction of cell death. NT, ΔCTSL, and ΔWDR81 cells were infected with VSV (GFP) (A) or VSV-EBO GP (GFP) (B) at 5 PFUs/cell. At 18 and 26 h post infection (hpi), the relative cell viability was measured using the CellTiter-Glo Luminescent Cell
Andrew T. Abad (12279897), Anthony J. Snyder (12279894), Pranav Danthi (246333)   +2 more
core   +1 more source

Optimized intramuscular immunization with VSV-vectored spike protein triggers a superior immune response to SARS-CoV-2. [PDF]

, 2022
Immunization with vesicular stomatitis virus (VSV)-vectored COVID-19 vaccine candidates expressing the SARS-CoV-2 spike protein in place of the VSV glycoprotein relies implicitly on expression of the ACE2 receptor at the muscular injection site. Here, we
Berenguer Veiga, Inês, Devisme, Christelle, Charaf Benarafa, Gert Zimmer, Plattet, Philippe, Boss, Renate, Adriano Taddeo, Benarafa, Charaf, Thiel, Volker, Inês Berenguer Veiga, Zimmer, Gert, Sebastian Weigang, Veiga, Inês Berenguer, Volker Thiel, Renate Boss, Weigang, Sebastian, Taddeo, Adriano, Georg Kochs, Christelle Devisme, Kochs, Georg, Philippe Plattet   +20 more
core   +1 more source

Immunovirotherapy Based on Recombinant Vesicular Stomatitis Virus: Where Are We?

Frontiers in Immunology, 2022
Vesicular stomatitis virus (VSV), a negative-strand RNA virus of the Vesiculovirus genus, has demonstrated encouraging anti-neoplastic activity across multiple human cancer types.
Yuguo Zhang, Bolni Marius Nagalo, Bolni Marius Nagalo   +2 more
doaj   +1 more source

Usp18 Expression in CD169⁺ Macrophages is Important for Strong Immune Response after Vaccination with VSV-EBOV

Vaccines, 2020
Ebola virus epidemics can be effectively limited by the VSV-EBOV vaccine (Ervebo) due to its rapid protection abilities; however, side effects prevent the broad use of VSV-EBOV as vaccine.
Sarah-Kim Friedrich, Rosa Schmitz, Michael Bergerhausen, Judith Lang, Lamin B. Cham, Vikas Duhan, Dieter Häussinger, Cornelia Hardt, Marylyn Addo, Marco Prinz, Kenichi Asano, Philipp Alexander Lang, Karl Sebastian Lang   +12 more
doaj   +1 more source

Regulated control of virus replication by 4-hydroxytamoxifen-induced splicing

Frontiers in Microbiology, 2023
Designing a modified virus that can be controlled to replicate will facilitate the study of pathogenic mechanisms of virus and virus–host interactions.
Zhenghao Zhao, Busen Wang, Shipo Wu, Zhe Zhang, Yi Chen, Jinlong Zhang, Yudong Wang, Danni Zhu, Danni Zhu, Yao Li, Jinghan Xu, Lihua Hou, Wei Chen   +12 more
doaj   +1 more source