Vesicular Stomatitis Virus (VSV) Therapy of Tumors [PDF]
AbstractVesicular stomatitis virus (VSV) is an essentially nonpathogenic negative‐stranded RNA virus, the replication of which is extremely sensitive to the antiviral effects of interferon (IFN). We demonstrate here that VSV selectively induces the cytolysis of numerous transformed human cell lines in vitro, with all the morphological characteristics ...
S, Balachandran, G N, Barber
openaire +2 more sources
Immunovirotherapy Based on Recombinant Vesicular Stomatitis Virus: Where Are We?
Vesicular stomatitis virus (VSV), a negative-strand RNA virus of the Vesiculovirus genus, has demonstrated encouraging anti-neoplastic activity across multiple human cancer types.
Yuguo Zhang +2 more
doaj +1 more source
Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden +22 more
core +1 more source
Regulated control of virus replication by 4-hydroxytamoxifen-induced splicing
Designing a modified virus that can be controlled to replicate will facilitate the study of pathogenic mechanisms of virus and virus–host interactions.
Zhenghao Zhao +12 more
doaj +1 more source
Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation [PDF]
Macrophages are key targets of HIV-1 infection. We have previously described that the expressionof CC chemokine ligand 2 (CCL2) increases during monocyte differentiation to macrophages and it is furtherup-modulated by HIV-1 exposure.
Andreotti, Mauro +15 more
core +3 more sources
Ebola virus epidemics can be effectively limited by the VSV-EBOV vaccine (Ervebo) due to its rapid protection abilities; however, side effects prevent the broad use of VSV-EBOV as vaccine.
Sarah-Kim Friedrich +12 more
doaj +1 more source
Spinor Algebras and Extended Superconformal Algebras [PDF]
We consider supersymmetry algebras in arbitrary spacetime dimension and signature. Minimal and maximal superalgebras are given for single and extended supersymmetry.
Lledo, M. A., Varadarajan, V. S.
core +3 more sources
[Objective] To evaluate the efficacy of ultraviolet-C (UVC) irradiation in inactivating porcine parvovirus (PPV), encephalomyocarditis virus (EMCV), pseudorabies virus (PRV) and vesicular stomatitis virus (VSV) within von Willebrand factor (vWF ...
ZHANG Yalu +3 more
doaj +1 more source
Autophagy gene activity may act as a key factor for sensitivity of tumor cells to oncolytic vesicular stomatitis virus [PDF]
Background: Beclin1 is an important, primary molecule for autophagy. Objectives: It is suggested that the control of the autophagy path increases the sensitivity of tumor cells to VSV.
Arefian, E. +3 more
core +2 more sources
Oncolytic Recombinant Vesicular Stomatitis Virus (VSV) Is Nonpathogenic and Nontransmissible in Pigs, a Natural Host of VSV [PDF]
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Lauro, Velazquez-Salinas +5 more
openaire +2 more sources

