Results 51 to 60 of about 48,453 (241)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Spin Transition of Iron in Deep‐Mantle Ferromagnesite

open access: yesGeophysical Monograph Series, Page 115-125., 2020

This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.

Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions

Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Jiachao Liu, Suyu Fu, Jung‐Fu Lin
wiley  

+1 more source

Different proteasome inhibitors affect VSV replication.

open access: yes, 2013
(A) Proteasome inhibitor 1 and Bortezomib decreased VSV replication. Titration of VSV from the medium of overnight infected HeLa cells. VSV infection (MOI = 1) for one hour was substituted by the regular medium with indicated concentration of proteasome ...
Nickolay Neznanov (377911)   +6 more
core   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He   +9 more
wiley   +1 more source

The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells. [PDF]

open access: yesPLoS ONE, 2017
Vesicular stomatitis virus (VSV) release from infected cells is inhibited by the interferon (IFN)-inducible antiviral host cell factor tetherin (BST-2, CD317).
Constantin Brinkmann   +6 more
doaj   +1 more source

The relationship between target strength frequency response and vertical swim velocity: a new approach for fish discrimination

open access: yesAquatic Living Resources, 2021
In-situ identification of fish species using acoustic methods is a key issue for fisheries research and ecological applications. We propose a novel approach to fish discrimination based on the relationship between target strength frequency response (TS(f)
Homma Hikaru, Ostrovsky Ilia
doaj   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Immunogenicity in African Green Monkeys of M Protein Mutant Vesicular Stomatitis Virus Vectors and Contribution of Vector-Encoded Flagellin

open access: yesVaccines, 2018
Recombinant vesicular stomatitis virus (VSV) is a promising platform for vaccine development. M51R VSV, an attenuated, M protein mutant strain, is an effective inducer of Type I interferon and dendritic cell (DC) maturation, which are desirable ...
Marlena M. Westcott   +4 more
doaj   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

Effects of loss of UGCG on infections by VSV pseudoviruses bearing the glycoproteins of measles virus, VSV, and EBOV.

open access: yes, 2020
Pseudoviruses were generated using a VSV helper virus encoding GFP and the indicated viral glycoprotein(s). Pseudoviruses were then adhered to prechilled cells assisted by centrifugation at 4°C for 1 hour.
William Casey Harrison (8423064)   +10 more
core   +1 more source

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