Results 71 to 80 of about 43,668 (144)

A vesicular stomatitis virus-based African swine fever vaccine prototype effectively induced robust immune responses in mice following a single-dose immunization

Frontiers in Microbiology
IntroductionAfrican swine fever (ASF) is a highly contagious hemorrhagic fever disease in pigs caused by African swine fever virus (ASFV). It is very difficult to control and prevent ASF outbreaks due to the absence of safe and effective vaccines ...
Yunyun Ma, Yunyun Ma, Junjun Shao, Wei Liu, Shandian Gao, Decai Peng, Chun Miao, Sicheng Yang, Zhuo Hou, Guangqing Zhou, Xuefeng Qi, Huiyun Chang   +11 more
doaj   +1 more source

HIV‐1 Vpr Drives a B Cell‐Like Phenotype in Primary CD4+ T Cells

MedComm, Volume 7, Issue 10, October 2026.
During acute HIV‐1 infection, Vpr induces transcriptional and epigenetic remodeling of primary CD4+ T cells, activating a transient B cell‐like program characterized by CD19, MS4A1, CD22, and PAX5 expression and increased chromatin accessibility at lymphocyte differentiation genes.
Peipei Wang, Jieying Li, Wei Wang, Zhuoyue Meng, Huixin Wu, Shumin Du, Kai Deng, Jinfeng Cai   +7 more
wiley   +1 more source

Crustal Shear‐Wave Velocity and Azimuthal Anisotropy Imaging Reveals the Merapi‐Merbabu‐Telomoyo Volcanic Chain, Central Java

Geophysical Research Letters, Volume 53, Issue 18, 28 September 2026.
Abstract We present new results from ambient noise tomography and azimuthal anisotropy analysis of the DOMERAPI data set to investigate crustal structure beneath the Merapi‐Merbabu‐Telomoyo region in central Java. The 3D shear‐wave velocity (Vs) model reveals a prominent high‐Vs anomaly extending from south of Merapi through Merbabu to Telomoyo ...
Iqwal Ramadhan, Sri Widiyantoro, Zulfakriza, Jean‐Philippe Metaxian, Nicholas Rawlinson, Jean‐Paul Montagner, Tedi Yudistira   +6 more
wiley   +1 more source

Employing the Oncolytic Vesicular Stomatitis Virus in Cancer Virotherapy: Resistance and Clinical Considerations

Viruses
Vesicular Stomatitis Virus (VSV) has emerged as a promising candidate for various clinical applications, including vaccine development, virus pseudotyping, and gene delivery. Its broad host range, ease of propagation, and lack of pre-existing immunity in
Alaa A. Abdelmageed, Stephen Dewhurst, Maureen C. Ferran   +2 more
doaj   +1 more source

The oncolytic vesicular stomatitis virus VSV-GP shows profound oncolytic activity in NUT-carcinoma cell lines

Molecular Therapy: Oncology
NUT carcinoma (NC) is a rare, yet aggressive disease (median survival of 6.5 months) of the young defined by a translocation of the nuclear protein in testis gene 1 (NUTM1).
Rieka C. Buchenau, Anne M. Schiller, Julia Beil, Susanne Berchtold, Andrea Schenk, Irina Smirnow, Mary E. Carter, Martin Schaller, Birgit Fehrenbacher, Anneli Vollert, Benjamin Schoeps, Rainer Kleemann, Ulrich M. Lauer, Linus D. Kloker   +13 more
doaj   +1 more source

Oncolytic vesicular stomatitis virus alone or in combination with JAK inhibitors is effective against ovarian cancer

Molecular Therapy: Oncology
Therapy-resistant ovarian cancers have a poor prognosis and novel effective treatment options are urgently needed. In this study, we evaluated the therapeutic efficacy of the oncolytic vesicular stomatitis virus (VSV) against a panel of patient-derived ...
Karen Geoffroy, Victor Mullins-Dansereau, Kim Leclerc-Desaulniers, Mélissa Viens, Marie-Claude Bourgeois-Daigneault   +4 more
doaj   +1 more source

ATG7 Limits Basal Antiviral Gene Expression and Moderately Promotes VSV Replication in Mammalian Non-Immune Cells

Pathogens
The autophagy regulator ATG7 helps maintain cellular homeostasis and has been suggested to modulate aspects of antiviral immune responses. In Drosophila, ATG7-dependent autophagy contributes to host resistance to vesicular stomatitis virus (VSV), a ...
Xiaohan Tong, Ruixue Wang, Yaxin Liu, Malia B. Potts, Shondra M. Pruett-Miller, Michael A. Whitt, Weikuan Gu, Kui Li   +7 more
doaj   +1 more source

Transcriptome analysis of long non-coding RNA and mRNA Profiles in VSV-infected BHK-21 Cells

BMC Genomics
Background Vesicular stomatitis virus (VSV) is a typical non-segmented negative-sense RNA virus of the genus Vesiculovirus in the family Rhabdoviridae. VSV can infect a wide range of animals, including humans, with oral blister epithelial lesions. VSV is
Wuweiyi Han, Xiaojuan Fei, Fan Yang, Xintong Sun, Jianshe Yang, Jinxin Qiu, Luhua Zhang, Wenhui Zhang, Guohua Chen, Wei Han, Xiaobo He, Yongsheng Liu, Weike Li   +12 more
doaj   +1 more source

Ginsenoside Rh1 Suppresses Vesicular Stomatitis Virus Replication by Inhibiting Autophagy to Promote Immune Responses

Microorganisms
Vesicular stomatitis virus (VSV), a member of the Vesiculovirus genus within the Rhabdoviridae family, is a widespread pathogen affecting all hoofed livestock species, leading to reduced animal growth and productivity.
Hongmei Chen, Qinglu Zhao, Dingcheng Wei, Zhanying Hu, Xueliang Zhu, Rui Zhang   +5 more
doaj   +1 more source

SARS-CoV-2 spike-armed vesicular stomatitis virus recapitulates severe COVID-19 acute respiratory distress syndrome in mice. [PDF]

iScience
Karunamurthy P, Tieu A, Chwastek D, Fisk ZA, Chander N, Jahandideh F, Engelberts D, Jamieson T, Petryk J, He X, Ilkow C, Poutou J, Lansdell C, Stewart DJ, Lalu MM.   +14 more
europepmc   +1 more source