Results 71 to 80 of about 34,623 (230)

Propofol Modulates Fear Memory Reconsolidation by Inhibiting D2 Receptor‐Expressing Neurons in the Medial Prefrontal Cortex

Advanced Science, EarlyView.
This study shows that propofol modulates fear‐memory reconsolidation in mice. It works by suppressing D2 receptor‐expressing neurons within the medial prefrontal cortex and their connections to the basolateral amygdala. D2‐receptor agonists reproduce this fear‐reducing effect, offering potential non‐anesthetic therapeutic strategies for trauma‐related ...
Jie Li, Yi‐Ge Guo, Xing Xu, Gui‐Lin Meng, Han Li, Liu‐Wei Chu, Xin‐Yuan Chen, Xiao‐Yun Guo, Tao Xu, Ti‐Fei Yuan, Ji Hu, Xiao‐Na Zhu   +11 more
wiley   +1 more source

ERK1/2 mediates the anorexigenic effect of leptin in the VTA of rats.

, 2013
Direct leptin infusion to the VTA of rats caused a significant decrease in food intake, while pretreatment with U0126 ICV blocked this effect. Treatment groups include: vehicleICV/vehicleVTA (open bars; n = 13), U0126ICV/vehicleVTA (open-striped bars; n =
Douglas J. Guarnieri (340247), Robert M. Sears (221997), Geliang Gan (45926), Richard Trinko (340244), Ralph J. DiLeone (222007), Xiao-Bing Gao (340246)   +5 more
core   +1 more source

Conceptual design of the high-flux VTA-2 test assembly for FMIT [PDF]

, 1983
This report describes the conceptual design of the test module for the high neutron flux vertical test assembly (VTA-2). The description emphasizes the thermal control systems available for monitoring test specimen temperatures at any desired temperature
Vogel, M.A.
core   +1 more source

The Formation and Function of the VTA Dopamine System

International Journal of Molecular Sciences
The midbrain dopamine system is a sophisticated hub that integrates diverse inputs to control multiple physiological functions, including locomotion, motivation, cognition, reward, as well as maternal and reproductive behaviors. Dopamine is a neurotransmitter that binds to G-protein-coupled receptors.
Guoqiang Hou, Mei Hao, Jiawen Duan, Ming-Hu Han   +3 more
openaire   +2 more sources

Ventral tegmental area amylin / calcitonin receptor signaling suppresses feeding and weight gain in female rats

Neuroscience Research
The pancreatic peptide amylin promotes negative energy balance in part through activation of amylin receptors (AmyRs) expressed in the ventral tegmental area (VTA), but studies have been limited to male rodents.
Tyler J. Gustafson, Lauren E. McGrath, Matthew R. Hayes, Elizabeth G. Mietlicki-Baase   +3 more
doaj   +1 more source

Programming of deep brain stimulation of the centromedian nucleus of the thalamus for drug‐resistant epilepsy: A meta‐analysis and proposed programming framework

Epilepsia, EarlyView.
Abstract Objective Although the centromedian nucleus of the thalamus (CM) is an increasingly considered deep brain stimulation (DBS) target for drug‐resistant epilepsy (DRE), there is significant variability in programming practices, which may contribute to heterogenous outcomes.
Mohammed A. AlQahtani, Michal Stern‐Zimmer, Puneet Jain, Suvasini Sharma, Alfonso Fasano, Alexander Rotenberg, George M. Ibrahim, Carolina Gorodetsky   +7 more
wiley   +1 more source

Organic electrochemical transistors for neural recording and modulation: From mixed‐conduction physics to closed‐loop biointerfaces

InfoMat, EarlyView.
OECT‐based neural interfaces integrate mixed ionic‐electronic transduction, soft biointegration, multimodal sensing, and closed‐loop modulation, enabling adaptive recording, neurochemical monitoring, and intelligent therapeutic strategies. Abstract Next‐generation neural interfaces increasingly aim to couple neural recording with local processing and ...
Chao Zhao, Zhongqing Sun, Shijie Wang, Bingjun Wang, Zixuan Yuan, Yaomin Guo, Jie Zhao, Leyuan Li, Xiaomu Wang, Wen Jiang, Wei Ma   +10 more
wiley   +1 more source

7 T MRI Connectivity‐Guided Reprogramming Improves Deep Brain Stimulation Motor Outcome in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established treatment for Parkinson's disease (PD). Using 7‐Tesla (7 T) MRI connectivity analysis to visualize the patient‐specific STN motor subdivision, we hypothesize that reprogramming patients who are stimulated outside of this subdivision can improve their ...
Yarit Wiggerts, Annabel van der Weide, Rick Schuurman, Pepijn van den Munckhof, Rob MA de Bie, Martijn Beudel, Maarten Bot   +6 more
wiley   +1 more source

The Effect of Chronic Ethanol on VTA GABA Neurons [PDF]

, 2017
The current accepted model for addiction in the brain is the dysregulation of dopamine (DA) in the mesolimbic pathway, which begins in the ventral tegmental area (VTA) and projects to the nucleus accumbens (NAc).
Steffensen, Scott, Bair, Stephanie
core  

Cardiac disease and prognosis associated with ventricular tachyarrhythmias in young adults and adults

BMC Cardiovascular Disorders, 2022
Background This study evaluates cardiac diseases and prognosis in young adults and adults presenting with ventricular tachyarrhythmias (VTA). Methods The present longitudinal, observational, registry-based, monocentric cohort study includes all ...
Kathrin Weidner, Michael Behnes, Tobias Schupp, Jorge Hoppner, Ibrahim El-Battrawy, Uzair Ansari, Ahmad Saleh, Gabriel Taton, Linda Reiser, Armin Bollow, Thomas Reichelt, Dominik Ellguth, Niko Engelke, Thomas Bertsch, Dirk Große Meininghaus, Ursula Hoffmann, Ibrahim Akin   +16 more
doaj   +1 more source